Cobalamin level is related to self-reported and clinically rated mood and to syndromal depression in bereaved HIV-1+ and HIV-1- homosexual men

Journal of Psychosomatic Research

Volumn 48, Issue 2, 2000, Pages 177-185

  Baldewicz, Teri T ^a   Goodkin, Karl ^b,c   Blaney, Nancy T ^b   Shor Posner, Gail ^b   Kumar, Mahendra ^b,c   Wilkie, Frances L ^b   Baum, Marianna K ^b   Eisdorfer, Carl ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Department of Biology   (United States)

Author keywords

Anxiety; Cobalamin; Depression; Distress; HIV 1 infection; Vitamin B12

Indexed keywords

COBALAMIN;

ADULT; ANXIETY; ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; CYANOCOBALAMIN DEFICIENCY; DEPRESSION; DISEASE ASSOCIATION; DISTRESS SYNDROME; HEALTH STATUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; SELF EVALUATION; VITAMIN BLOOD LEVEL;

ADAPTATION, PSYCHOLOGICAL; ADULT; BEREAVEMENT; DEPRESSION; HIV SERONEGATIVITY; HIV SEROPOSITIVITY; HIV-1; HOMOSEXUALITY, MALE; HUMANS; MALE; MOOD DISORDERS; PSYCHIATRIC STATUS RATING SCALES; SELF ASSESSMENT (PSYCHOLOGY); SOCIAL SUPPORT; STRESS, PSYCHOLOGICAL; VITAMIN B 12;

EID: 0034037065     PISSN: 00223999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3999(99)00108-7     Document Type: Article

References (58)

1. Dommisse J. Subtle vitamin-B12 deficiency and psychiatry. a largely unnoticed but devastating relationship? Med Hypothes. 34:1991;131-140.
2. Ellis F.R., Nasser S. A pilot study of vitamin-B12 in the treatment of tiredness. Br J Nutr. 30:1973;277-283.
3. Herbert V., Das K.C. Folic acid and vitamin B12. Shils M.E., Olson J.A., Shike M. Modern nutrition in health and disease. 1994;Lea & Febiger, Philadelphia.
4. Lindenbaum J., Healton E.B., Savage D.G.et al. Neuropsychiatric disorders caused by cobalamin deficiency in the absence of pernicious anemia or macrocytosis. N Engl J Med. 318:1988;1720-1728.
5. Beach R.S., Morgan R., Wilkie F.et al. Plasma vitamin B12 level as a potential cofactor in studies of human immunodeficiency virus type 1-related cognitive changes. Arch Neurol. 49:1992;501-506.
6. Healton E.B., Savage D.G., Brust J.C., Garrett T.J., Lindenbaum J. Neurologic aspects of cobalamin deficiency. Medicine. 70:1991;229-245.
7. Saracaceanu E., Tramoni A.V., Henry J.M. An association between subcortical dementia and pernicious anemia - a psychiatric mask. Compreh Psychiatry. 38:1997;349-351.
8. Bell I.R., Edman J.S., Miller J.et al. Relationship of normal serum vitamin B12 and folate levels to cognitive test performance in subtypes of geriatric major depression. J Geriatr Psychiatry Neurol. 3:1990;98-105.
9. Bell I.R., Edman J.S., Morrow F.D.et al. B complex vitamin patterns in geriatric and young adult inpatients with major depression. J Am Geriatr Soc. 39:1991;252-257.
10. Perkins D.O., Stern R.A., Golden R.N., Murphy C., Naftolowitz D., Evans D.L. Mood disorders in HIV infection. prevalence and risk factors in a nonepicenter of the AIDS epidemic Am J Psychiatry. 151:1994;233-236.
11. Robertson K.R., Stern R.A., Hall C.D.et al. Vitamin B12 deficiency and nervous system disease in HIV infection. Arch Neurol. 50:1993;807-811.
12. Newbold H.L. Vitamin B-12. placebo or neglected therapeutic tool? Med Hypothes. 28:1989;155-164.
13. Carethers M. Diagnosing vitamin B12 deficiency. a common geriatric disorder Geriatrics. 43:1988;89-112.
14. Hector M., Burton J.R. What are the psychiatric manifestations of vitamin B12 deficiency? J Am Geriatr Soc. 36:1988;1105-1112.
15. Levitt A.J., Joffe R.T. Vitamin B12 in psychotic depression. Br J Psychiatry. 153:1988;266-267.
16. Geagea K., Ananth J. Response of a psychiatric patient to vitamin B12 therapy. Dis Nerv Syst. 36:1975;343-344.
17. Verbanck P.M., Oliver L. Changing psychiatric symptoms in a patient with vitamin B12 deficiency. J Clin Psychiatry. 52:1991;182-183.
18. Evans D.L., Edelsohn G.A., Golden R.N. Organic psychosis without anemia or spinal cord symptoms in patients with vitamin B12 deficiency. Am J Psychiatry. 140:1983;218-221.
19. Phillips S.L., Kahaner K.P. An unusual presentation of vitamin B12 deficiency. Am J Psychiatry. 145:1988;529.
20. Zucker D.K., Livingston R.L., Nakra R., Clayton P.J. B12 deficiency and psychiatric disorders. case report and literature review Biol Psychiatry. 16:1981;197-205.
21. 12 absorption in patients with AIDS. Am J Hematol. 34:1990;132-139.
22. Harriman G.R., Smith P.D., Horne M.K.et al. Vitamin B12 malabsorption in patients with acquired immunodeficiency syndrome. Arch Int Med. 149:1989;2039-2041.
23. Goodkin K. Psychoneuroimmunology and viral infection with a special note on AIDS. Balner H. Publications of the Helen Dowling Institute for biopsychosocial medicine. 1. A new medical model. A challenge for biomedicine? 1990;53-64 Swets & Zeitlinger, Rockville, Maryland.
24. Blaney N.T., Goodkin K., Morgan R.et al. A stress moderator model of distress in early HIV-1 infection. concurrent analysis of life events, hardiness, and social support J Psychosom Res. 35:1991;297-305.
25. Goodkin K., Antoni M.H., Sevin B., Fox B.H. A partially testable, predictive model of psychosocial factors in the etiology of cervical cancer. I. Biological, psychological, and social aspects. Psycho-oncology. 2:1993;79-98.
26. Goodkin K., Antoni M.H., Sevin B., Fox B.H. A partially testable, predictive model of psychosocial factors in the etiology of cervical cancer. II. Bioimmunological, psychoimmunological, and socioimmunological aspects, critique and perspective integration. Psycho-oncology. 2:1993;99-121.
27. Baldewicz T., Goodkin K., Feaster D.J.et al. Plasma pyridoxine activity is related to psychological distress in recently bereaved homosexual men. Psychosom Med. 60:1998;297-308.
28. Shor-Posner G., Feaster D., Blaney N.T.et al. Impact of vitamin B6 on psychological distress in a longitudinal study of HIV-1 infection. Int J Psychiatry Med. 24:1994;209-222.
29. Vitamin B12/folate kit. 1995;Chiron Diagnostic Corporation, Norwood, Massachusetts.
30. McNair D.M., Lorr M., Droppleman L.F. Manual for the profile of mood states. 1971;Educational and Industrial Testing Service, San Diego, California.
31. Williams J.B.W. A structured interview guide for the Hamilton Depression and Anxiety scales. Arch Gen Psychiatry. 45:1988;742-746.
32. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry. 23:1960;56-61.
33. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychology. 32:1959;50-55.
34. Spitzer R.B., Williams J.B., Gibbon M. Structured clinical interview for the DSM-III-R. 1988;American Psychiatric Press, Washington, DC.
35. Sarason I.G., Johnson J.H., Siegel J.M. Assessing the impact of life changes. development of the life experiences survey J Consult Clin Psychol. 46:1978;932-946.
36. Sarason B.R., Shearin E.N., Pierce G.R., Sarason I.G. Interrelations of social support measures. theoretical and practical implications J Pers Soc Psychol. 52:1987;813-832.
37. Carver C.S., Scheier M.F., Weintraub J.K. Assessing coping strategies. a theoretically based approach J Pers Soc Psychol. 56:1989;267-283.
38. Lifshitz M.S., de Cresce R.P. The QM-300 protein analysis system. Clin Lab Med. 8:1988;633-642.
39. Skaler J.H., Gertz D., Waring P.P. An automated continuous flow procedure for simultaneous measurement of erythrocyte alanine and aspartate amino-transferase activities. Nutr Res. 7:1987;31-41.
40. 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. Morbid Mortal Weekly Rep. 41:1992;1-19.
41. SAS/STAT user's guide, version 6. 5th ed:1997;SAS Institute, Cary, North Carolina.
42. Shor-Posner G., Morgan R., Wilkie F., Eisdorfer C., Baum M.K. Plasma cobalamin levels affect information processing speed in a longitudinal study of HIV-1 disease. Arch Neurol. 52:1995;195-198.
43. Goodkin K. Complications of the central and peripheral nervous systems. Forstein M. HIV-related neuropsychiatric complications and treatments. HIV/AIDS training curriculum. 1995;1-103 American Psychiatric Association, Washington, DC.
44. Luizzi G.M., Mastoianni C.M., Fanelli M.et al. Myelin degrading activity in the CSF of HIV-1-infected patients with neurological diesases. NeuroReport. 6:1994;157-160.
45. Combs G.F. The vitamins. fundamental aspects in nutrition and health:1992;Academic Press, San Diego, California. pp. 377-92.
46. Fava M., Borus J.S., Alpert J.E., Nierenberg J.A., Rosenbaum J.F., Bottiglieri T. Folate, vitamin B12, and homocysteine in major depressive disorder. Am J Psychiatry. 154:1997;426-428.
47. Alpert J.E., Fava M. Nutrition and depression. the role of folate Nutr Rev. 55:1997;145-149.
48. Cantoni G.L., Mudd S.H., Andreoli V. Affective disorders and S-adenosylmethionine. a new hypothesis Trends Neurosci. 12:1989;319-324.
49. DiRocco A., Tagliati M., Danisis F., Dorfman D., Noise J., Simpson D.M. A pilot study of L-methionine for the treatment of AIDS-associated myelopathy. Neurology. 51:1988;266-268.
50. Burkes R.L., Cohen H., Krailo M., Sinow R.M., Carmel R. Low serum cobalamin levels occur frequently in the acquired immune deficiency syndrome and related disorders. Eur J Haematol. 38:1987;141-147.
51. Baum M.K., Shor-Posner G., Lu Y.et al. Micronutrients and HIV-1 disease progression. AIDS. 9:1995;1051-1056.
52. Wickramasinghe S.N. Morphology, biology, and biochemistry of cobalamin- and folate-deficient bone marrow cells. Bailliere's Clin Haematol. 8:1995;441-459.
53. Tang A.M., Graham N.M., Chandra R.K., Saah A.J. Low serum B-12 concentrations are associated with faster human immunodeficiency virus type 1 (HIV-1) disease progression. J Nutr. 127:1997;345-351.
54. Baum M.K., Shor-Posner G., Lai S.et al. High risk of HIV-related mortality is associated with selenium deficiency. J AIDS Hum Retrovirol. 15:1997;370-374.
55. Nijst T.Q., Wevers R.A., Schoonderwaldt H.C., Hommes O.R., de Haan A.F.J. Vitamin B12 and folate concentrations in serum and cerebrospinal fluid of neurological patients with special reference to multiple sclerosis and dementia. J Neurol Neurosurg Psychiatry. 53:1990;951-954.
56. Meadows M., Kaplan R.F., Bromfield E.B. Cognitive recovery with vitamin B12 therapy. a longitudinal neuropsychological assessment Neurology. 44:1994;1764-1765.
57. Kieburtz K.D., Giang D.W., Schiffer R.B., Vakil N. Abnormal vitamin B12 metabolism in human immunodeficiency virus infection. Arch Neurol. 48:1991;312-314.
58. Herzlich B.C., Schiano T.D. Reversal of apparent AIDS dementia complex following treatment with vitamin B12. J Intern Med. 233:1993;495-497.