Effects of acute and chronic administration of MCI-225, a new selective noradrenaline reuptake inhibitor with 5-HT3 receptor blocking action, on extracellular noradrenaline levels in the hypothalamus of stressed rats

Japanese Journal of Pharmacology

Volumn 83, Issue 1, 2000, Pages 31-38

  Wu, Ying Liang ^a,b   Yoshida, Masami ^a   Emoto, Hiroyuki ^a   Ishii, Hideo ^a   Koga, Kiminori ^a   Tanaka, Masatoshi ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Footshock stress; Hypothalamus; Intracerebral microdialysis; MCI 225; Noradrenaline

Indexed keywords

4 (2 FLUOROPHENYL) 6 METHYL 2 (1 PIPERAZINYL)THIENO[2,3 D]PYRIMIDINE; NORADRENALIN; SEROTONIN 3 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HYPOTHALAMUS; MALE; MICRODIALYSIS; NONHUMAN; NORADRENALIN BRAIN LEVEL; RECEPTOR BLOCKING; SHOCK; STRESS;

ADRENERGIC UPTAKE INHIBITORS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOTHALAMUS; MALE; NOREPINEPHRINE; PIPERAZINES; PYRIMIDINES; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN ANTAGONISTS; STRESS;

EID: 0034036196     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.83.31     Document Type: Article

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