Apparent change in ion selectivity caused by changes in intracellular K+ during whole-cell recording

Biophysical Journal

Volumn 78, Issue 4, 2000, Pages 1872-1880

  Frazier, Charles J ^a   George, Eric G ^a   Jones, Stephen W ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM ION;

ARTICLE; HUMAN; HUMAN CELL; MEMBRANE CURRENT; MEMBRANE DEPOLARIZATION; POTASSIUM CELL LEVEL; POTASSIUM CURRENT; SODIUM CURRENT;

EID: 0034034772     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76736-1     Document Type: Article

References (17)

1. Crank, J. 1956. The Mathematics of Diffusion. Clarendon Press, Oxford.
2. Fedida, D., N. D. Maruoka, and S. Lin. 1999. Modulation of slow inactivation in human cardiac Kv1.5 channels by extra-and intracellular permeant cations. J. Physiol. (Lond.). 515:315-329.
3. Frankenhaeuser, B., and A. L. Hodgkin. 1956. The after-effects of impulses in the giant nerve fibers of Loligo. J. Physiol. (Lond.). 131:341-376.
4. +. Soc. Neurosci. Abstr. 24:2034.
5. Hille, B. 1992. Ionic Channels of Excitable Membranes. Sinauer Associates, Sunderland, MA.
6. Hodgkin, A. L., and A. F. Huxley. 1952. The components of membrane conductance in the giant axon of Loligo. J. Physiol. (Land.). 116: 473-496.
7. Kiss, L., J. LoTurco, and S. J. Korn. 1999. Contribution of the selectivity filter to inactivation in potassium channels. Biophys. J. 76:253-263.
8. Klemic, K. G., C. C. Shieh, G. E. Kirsch, and S. W. Jones. 1998. Inactivation of Kv2.1 potassium channels. Biophys. J. 74:1779-1789.
9. Korn, S. J., and S. R. Ikeda. 1995. Permeation selectivity by competition in a delayed rectifier potassium channel. Science. 269:410-412.
10. Mathias, R. T., I. S. Cohen, and C. Oliva. 1990. Limitations of the whole cell patch clamp technique in the control of intracellular concentrations. Biophys. J. 58:759-770.
11. Orkand, R. K. 1980. Extracellular potassium accumulation in the nervous system. Fed. Proc. 39:1515-1518.
12. Pusch, M., and E. Neher. 1988. Rates of diffusional exchange between small cells and a measuring patch pipette. Pflügers Arch. 411:204-211.
13. Ríos, E., and M. D. Stern. 1997. Calcium in close quarters: microdomain feedback in excitation-contraction coupling and other cell biological phenomena. Anna. Rev. Biophys. Biomol. Struct. 26:47-82.
14. Starkus, J. G., L. Kuschel, M. D. Rayner, and S. H. Heinemann. 1997. Ion conduction through C-type inactivated Shaker channels. J. Gen. Physiol. 110:539-550.
15. + currents in the "nonconducting" Shaker potassium channel mutant W434F. J. Gen. Physiol. 112:85-93.
16. Strikwerda, J. C. 1989. Finite Difference Schemes and Partial Differential Equations. Wadsworth and Brooks/Cole, Pacific Grove, CA.
17. Wang, L. Y., L. Gan, T. M. Perney, I. Schwartz, and L. K. Kaczmarek. 1998. Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion. Proc. Natl. Acad. Sci. USA. 95:1882-1887.