Different effects of dominant negative mutants of desmocollin and desmoglein on the cell-cell adhesion of keratinocytes

Journal of Cell Science

Volumn 113, Issue 10, 2000, Pages 1803-1811

  Hanakawa, Yasushi ^a   Amagai, Masayuki ^b   Shirakata, Yuji ^a   Sayama, Koji ^a   Hashimoto, Koji ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Adherens junction; Desmocollin; Desmoglein; Desmosome; E cadherin

Indexed keywords

BETA CATENIN; CALCIUM; DESMOCOLLIN; DESMOGLEIN; DESMOPLAKIN; KERATIN; MUTANT PROTEIN; UVOMORULIN;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL AGGREGATION; CELL CULTURE; CONTROLLED STUDY; CYTOPLASM; DESMOSOME; FIBROBLAST; HUMAN; HUMAN CELL; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS RECOMBINANT;

ANIMALS; CADHERINS; CALCIUM; CELL ADHESION; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DESMOCOLLINS; DESMOGLEIN 3; DESMOGLEINS; DESMOPLAKINS; DESMOSOMES; DNA, COMPLEMENTARY; GAMMA CATENIN; GENETIC VECTORS; HUMANS; KERATINOCYTES; MICE; MUTATION; PRECIPITIN TESTS; PROTEIN STRUCTURE, TERTIARY; TIGHT JUNCTIONS;

ADENOVIRIDAE; ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0034034729     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Amagai, M., Klaus, K. V. and Stanley, J. R. (1991). Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell 67, 869-877.
2. Amagai, M., Karpati, S., Klaus, K. V., Udey, M. C. and Stanley, J. R. (1994). Extracellular domain of pemphigus vulgaris antigen (desmoglein 3) mediates weak homophilic adhesion. J. Invest. Dermatol. 103, 609-615.
3. Amagai, M., Fujimori, T., Masunaga, T., Shitnizu, H., Nishikawa, T., Shimizu, N., Takeichi, M. and Hashimoto, T. (1995). Delayed assembly of desmosomes in keratinocytes with disrupted classic-cadherin-mediated cell adhesion by a dominant negative mutant. J. Invest. Dermatol. 104, 27-32.
4. Amagai, M. (1996). Pemphigus: Autoimmunity to epidermal cell adhesion molecules. Advan. Dermatol. 11, 319-352.
5. Bierkamp, C., Schwarz, H., Huber, O. and Kemler, R. (1999). Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice. Development 126, 371-381.
6. Cowin, P., Mattey, D. and Garrod, D. (1984). Identification of desmosomal surface components (desmocollins) and inhibition of desmosome formation by specific Fab. J. Cell Sci. 70, 41-60.
7. Demlehner, M. P., Schafer, S., Grand, C. and Franke, W. W. (1995). Continual assembly of half desmosomal structures in the absence of cell contacts and their frustrated endocytosis: a coordinated Sisyphus cycle. J. Cell Biol. 131, 745-760.
8. Duden, R. and Franke, W. W. (1988). Organization of desmosomal plaque proteins in cells growing at low calcium concentrations. J. Cell Biol. 107, 1049-1063.
9. Gumbiner, B. M. (1996). Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84, 345-357.
10. Green, K. J. and Jones, J. C. (1996). Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB J. 10, 871-881.
11. Jones, J. C. R. and Goldman, R. D. (1985). Intermediate filaments and the initiation of desmosome assembly. J. Cell Biol. 101, 506-517.
12. Jou, T. S., Stewart, D. B., Stappert, J., Nelson, VV. J. and Marrs, J. A. (1995). Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex. Proc. Nat. Acad. Sci. USA 92, 5067-5071.
13. Kanegae, V., Takamori, K., Sato, Y., Lee, G., Nakai, M. and Saito, I. (1996). Efficient gene activation system on mammalian cell chromosomes using recombinant adenovirus producing Cre recombinase. Gene 181, 207-212.
14. Kowalczyk, A. P., Palka, H. L., Luu, H. H., Nilles, L. A., Anderson, J. E., Wheelock, M. J. and Green, K. J. (1994). Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability. J. Biol. Chem. 269, 31214-31223.
15. Kowalczyk, A. P., Borgwardt, J. E. and Green, K. (1996). Analysis of desmosomal cadherin-adhesive function and stoichiometry of desmosomal cadherin-plakoglobin complexes. J. Invest. Dermatol. 107, 293-300.
16. Lewis, J. E., Jensen, P. J. and Wheelock, M. J. (1994). Cadherin function is required for human keratinocytes to assemble desmosomes and stratify in response to calcium. J. Invest. Dermatol. 102, 870-877.
17. Miyake, S., Makimura, M., Kanegae, V., Harada, S., Sato, Y., Takamori, K., Tokuda, C. and Saito, I. (1996). Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Nat. Acad. Sci. USA 93, 1320-1324.