Unwinding of a herpes simplex virus type 1 origin of replication (Ori(S)) by a complex of the viral origin binding protein and the single- stranded DNA binding protein

Journal of Virology

Volumn 74, Issue 12, 2000, Pages 5726-5728

  He, Xiaodun ^a   Lehman, I R ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; INFECTED CELL PROTEIN 8; PROTEIN UL9; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DNA REPLICATION ORIGIN; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

BASE SEQUENCE; BINDING SITES; DNA HELICASES; DNA, SINGLE-STRANDED; DNA, VIRAL; DNA-BINDING PROTEINS; HERPESVIRUS 1, HUMAN; MODELS, GENETIC; MUTATION; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN BINDING; REPLICATION ORIGIN; TEMPERATURE; THERMODYNAMICS; VIRAL PROTEINS;

EID: 0034034279     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.12.5726-5728.2000     Document Type: Article

References (11)

1. Bayliss, G. J., H. S. Marsden, and J. Hay. 1975. Herpes simplex virus proteins: DNA-binding proteins in infected cells and in the virus structure. Virology 68:124-134.
2. Boehmer, P. E., M. S. Dodson, and I. R. Lehman. 1993. The herpes simplex virus type 1 origin binding protein: DNA helicase activity. J. Biol. Chem. 268: 1220-1225.
3. Bruckner, R. C., J. J. Crute, M. S. Dodson, and I. R. Lehman. 1991. The herpes simplex virus 1 origin binding protein: a DNA helicase. J. Biol. Chem. 266:2669-2674.
4. Dabrowski, C. E., and P. A. Schaffer. 1991. Herpes simplex virus type 1 origin-specific binding protein: oriS-binding properties and effects of cellular proteins. J. Virol. 65:3140-3150.
5. Elias, P., and I. R. Lehman. 1988. Interaction of origin binding protein with an origin of replication of herpes simplex virus 1. Proc. Natl. Acad. Sci. USA 85:2959-2963.
6. Fierer, D. S., and M. D. Challberg. 1992. Purification and characterization of UL9, the herpes simplex virus type 1 origin-binding protein. J. Virol. 66: 3986-3995.
7. Hernandez, T. R., R. E. Dutch, I. R. Lehman, C. Gustafsson, and P. Elias. 1991. Mutations in a herpes simplex virus type 1 origin that inhibit interaction with origin-binding protein also inhibit DNA replication. J. Virol. 65: 1649-1652.
8. Lee, S. S-K., and I. R. Lehman. 1997. Unwinding of the box I element of a herpes simplex virus type I origin by a complex of the virus origin binding protein, single-strand DNA binding protein, and single-stranded DNA. Proc. Natl. Acad. Sci. USA 94:2838-2842.
9. Lehman, I. R., and P. E. Boehmer. 1999. Replication of herpes simplex virus DNA. J. Biol. Chem. 274.28059-28062.
10. Olivo, P. D., N. J. Nelson, and M. D. Challberg. 1988. Herpes simplex virus DNA replication: the UL9 gene encodes an origin-binding protein. Proc. Natl. Acad. Sci. USA 85:5414-5418.
11. Quinn, J. P., and D. J. McGeoch. 1985. DNA sequence of the region of the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein. Nucleic Acids Res. 13:8143-8163.