Diastereo- and enantioselective synthesis of α-(β-aminoalkyl)- substituted γ-lactams by Michael addition to nitroalkenes

Synlett

Volumn , Issue 5, 2000, Pages 637-640

  Enders, Dieter ^a   Teschner, Pascal ^a   Raabe, Gerhard ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Asymmetric synthesis; Lactams; Michael addition; Nitroalkenes; Reduction

Indexed keywords

ALKENE DERIVATIVE; GAMMA LACTAM DERIVATIVE; LITHIUM;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; ENANTIOMER; NONHUMAN; REDUCTION; STEREOCHEMISTRY; SYNTHESIS; X RAY ANALYSIS;

EID: 0034033374     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

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27. Crystallographic data (excluding structure factors) for the structure reported in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication no. CDDC-140025. Copies of the data can be obtained free of charge on application to the Director, CCDC, 12 Union Road, Cambridge CB2 1EZ, UK, [fax: int. code+44(1223)336-033, e-mail: deposit@chemcrys.cam.ac.uk].
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32. 3: C 60.91, H 9.44, N 10.93. Found: C 60.54, H 9.70, N 11.36.
33. All new compounds showed suitable spectroscopic data (IR, NMR, MS) and correct elemental analyses.