Animal definition: A necessity for the validity of animal experiments?

Laboratory Animals

Volumn 34, Issue 2, 2000, Pages 121-130

  Obrink K J ^a   Rehbinder, C ^b   Waller, M ^c  

^a UPPSALA UNIVERSITY   (Sweden)

^b NATIONAL VETERINARY INSTITUTE   (Sweden)

^c NONE   (Sweden)

Author keywords

Animal definition; Feed back mechanisms; Homeostasis; Intrinsic factor

Indexed keywords

ACCURACY; ANIMAL EXPERIMENT; ANIMAL GENETICS; ANIMAL MODEL; ANIMAL WELFARE; ARTICLE; DISEASE MODEL; ENVIRONMENTAL FACTOR; ETHICS; EXPERIMENTAL ANIMAL; HOMEOSTASIS; HUMIDITY; IMMUNOSTIMULATION; ISOLATED ORGAN; LABORATORY; LIGHT; MEDICAL RESEARCH; METABOLISM; MONITORING; NEGATIVE FEEDBACK; NEUROENDOCRINE SYSTEM; NONHUMAN; NUTRITION; PRACTICE GUIDELINE; REPRODUCIBILITY; SKILL; STANDARDIZATION; STIMULUS RESPONSE; TEMPERATURE;

ANIMALIA;

EID: 0034032282     PISSN: 00236772     EISSN: None     Source Type: Journal    
DOI: 10.1258/002367700780457608     Document Type: Article

References (63)

1. Balch CM, Bleyer AW, Krakoff IH, Peters LJ (1990) The vital role of animal research in advancing cancer diagnosis and treatment. Cancer Bulletin 42, 266-9
2. Baumans V, van de Weerd HA (1996) Enrichment of laboratory animal housing: basic need or luxury? Scandinavian Journal of Laboratory Animal Science 23 (Suppl 1), 93-5
3. Bayne K (1997) AAALAC International accreditation: quality assurance through peer evaluation. In: Proceedings of the Sixth FELASA Symposium. 19-21 June 1996, Basel Switzerland (O'Donoghue PN, ed) London: Royal Society Medicine Press, pp 200-2
4. Bellhom RW (1980) Lighting in the animal environment. Laboratory Animal Science 30, 440-50
5. Berti T, Cima L (1955) Einfluss der temperature auf die pharmakologische wirkung des chlorproma zins. Artznermittelforschung 5, 73-4
6. Beynen AC (1985) Biochemists and the diet of their rats. Trends in Biochemical Sciences 10, 108-9
7. Brainard GC, Petterborg LJ, Richardson BA, Reiter RJ (1982) Pineal melatonin in Syrian hamsters: circadian and seasonal rhythms in animals maintained under laboratory and natural conditions. Neuroendocrinology 35, 342-8
8. Broderson JR, Lindssey JR, Crawford JE (1976) The role of environmental ammonia in respiratory mycoplasmosis of rats. American Journal of Pathology 85, 115-30
9. Cannon WB (1932) Wisdom of the Body. New York: WW Norton
10. Clark DJ, Rager DR, Calpin JP (1997) Animal well-being-I,II,III,IV. Laboratory Animal Science 47, 564-79
11. Close B (1996) Recommendation for euthanasia of experimental animals. Part 1. Laboratory Animals 30, 293-316
12. Clough G (1982) Environmental effects on animals used in biomedical research. Biological Reviews 57, 487-523
13. Dahlborn K, van Gils BAA, van de Weerd HA, van Dijk JE, Baumans V (1996) Evaluation of long-term environmental enrichment in the mouse. Scandinavian Journal of Laboratory Animal Science 23, (Suppl. 1), 97-106
14. Davson H (1951) A Textbook of General Physiology, 3rd edn. London: J. & A. Churchill Ltd
15. Deeny AA, McFarlane L, Russell RJ, Festing MW (1997) A comparison of polymerase chain reaction, DNA fingerprinting and biochemical marker techniques for routine genetic monitoring. In: Proceedings of the Sixth FELASA Symposium, 19-21 June 1996, Basel Switzerland (O'Donoghue PN, ed). London: Royal Society Medicine Press, pp 120-5
16. deVrey P (1997) The use of quality assurance systems in maintaining control over animal experiments. In: Proceedings of the Sixth FELASA Symposium, 19-21 June 1996, Basel, Switzerland (O'Donoghue PN, ed). London: Royal Society Medicine Press, pp 79-83
17. O'Donoghue PN (1988) The establishment of laboratory animal science in the United Kingdom In: Collected Papers to Celebrate LASA's 25th Anniversary (Seamer JH, ed). London: Royal Society of Medicine Services for Laboratory Animals Ltd, on behalf of the Laboratory Animal Association, pp 2-8
18. Donnelly H (1995) Quality in laboratory animals. In: Laboratory Animals. An Introduction for Experimenters, 2nd edn. (Tuffery AA, ed). Chichester: John Wiley & Sons, pp 181-203
19. Döhler K-D, Gärtner K, von zur Mühlen A, Döhler U (1977) Activation of anterior pituitary, thyroid and adrenal gland in rats after disturbance stress. Acta Endocrinologica 86, 489-97
20. Feinstein RE, Bucht E, Grimelius L, Iwarsson K, Rönnbäck C, Selking Ö, Sjöstedt U, Sjöberg H-E (1994) Blood sampling procedures influence serum calcitonin concentrations in rats. Journal of Endocrinology 141, 267-70
21. Fernstrom JD (1976) The effect of nutritional factors on brain amino acid levels and monoamine synthesis. Federation Proceedings 35, 1151-6
22. Festing M (1994) Reduction of animal use: experimental design and quality of experiment. Laboratory Animals 28, 212-21
23. Food and Drug Administration (1978) Good Laboratory Practice (GLP). Rockville, MD: Public Health Service, FDA
24. Fouts JR (1976) Overview of the field: environmental factors affecting chemical or drug effects in animals. Federation Proceedings 35, 1162-5
25. Fuhrman GJ, Fuhrman FA (1961) Effekts of temperature on the action of drugs. Annual Reviews in Pharmacology 1, 65-70
26. GV-SOLAS, Working committee for the biological characterization of laboratory animals (1985) Guidelines for specification of animals and husbandry methods when reporting the results of animal experiments. Laboratory Animals 19, 106-8
27. Gärtner K, Bonath K (1971) Der Einfluss der Gruppengrösse auf den Kortikosterongehalt der Nebennieren und des Serums männlicher Mäuse und Ratten. Endokrinologie 58, 129-39
28. Haataja H, Woipio H-M, Nevalainen A, Jantunen MJ, Nevalainen T (1989) Decidious woodchips as bedding material: estimation of dust yield, water absorption and a microbiological comparision. Scandinavian Journal of Laboratory Animal Science 3, 105-11
29. Harkness JE, Wagner JE (1989) The Biology and Medicine of Rabbits and Rodents, 3rd edn. Philadephia: Lea & Febiger
30. Hau J, Craver JFA (1994) Refinement in Laboratory Animal Science. It is a Cinderella subject, and is there conflict and imbalance within the 3 Rs? Scandinavian Journal of Laboratory Animal Science 4, 161-7
31. Home Office (1991) Statistics of Scientific Procedures on Living Animals Great Britain 1990. London: HMSO, Cm 1574
32. Hurni H (1969) Einflüsse von Umweltfaktoren auf das Versuchstier Aus: Das Versuchstier. Symp. Schweiz. Mikrobiol. Ges. 1968. Bibliotheca Mikrobiologica 7, 22-41
33. Iwarsson K, Rehbinder C (1993) A study of different euthanasia techniques in guinea pigs, rats and mice. Animal response and postmortem findings. Scandinavian Journal of Laboratory Animal Science 20, 191-205
34. Jones RB, Kacergis JB, MacDonald MR, McKnight FT, Turner WA, Ohman JL, Paigen B (1995) The effect of relative humidity on mouse allergen levels in an environmentally controlled mouse room. American Industrial Hygiene Association Journal 56, 398-401
35. Kalsbeek A, Buijs RM, Engelmann M, Wotjak CT, Landgraf R (1995) In vivo measurement of a diurnal variation in vasopressin release in the rat suprachiasmatic nucleus. Brain Research 682, 75-82
36. Koefoed-Johnsen V, Lyon I, Ussing HH (1973) Effect of Cu-ion on permeability properties of isolated frog skin (Rana Temporaria). Acta Physiologica Scan-dinavica Suppl. 396, 102
37. Kozhukhov AN (1986) Temperatur standardization in biomedical experiments. Tierlaboratorium 11, 42-71
38. Kraft V, Deeny AA, Blanchet HM, Boot R, Kornerup-Hansen A, Hem A, van Herck H, Kunstyr I, Milite G. Needham JR, Nicklas W, Perrot A, Rehbinder C, Richard Y, de Vroey G (1994) Recommendations for the health monitoring of mouse, rat, hamster, guineapig and rabbit breeding colonies. Laboratory Animals 28, 1-12
39. Lang CM, Vesell ES (1976) Environmental and genetic factors affecting laboratory animals; impact on biomedical research. Federation Proceedings 35, 1123-4
40. Lindsey JR, Conner MW, Baker HJ (1978) Physical, chemical and microbial factors affecting biologic response. National Academy of Sciences September 1976, pp 31-43
41. Nair V, Casper R (1969) The influence of light on daily rhythm in hepatic drug metabolising enzymes in rat. Life Sciences 8, 1291-8
42. Nebert DW, Felton JS (1976) Importance of genetic factors influencing the metabolism of foreign compounds. Federation Proceedings 35, 1133-41
43. Nevalainen T, Vartiainen T (1996) Volatile organic compounds in commonly used beddings before and after autoclaving Scandinavian Journal of Laboratory Animal Science 23, 101-4
44. Nielsen JB, Andersen O, Svendsen P (1986) Hepatic o-deethylase activity in mice on different types of bedding. Z. Versuchtierkunde 28, 69-75
45. Nielsen JB, Andersen O, Svendsen P (1988) Hepatic p-nitrophenetole o-dethylation activity in mice depends on diet composition. Scandinavian Journal of Laboratory Animal Science 15, 69-79
46. Nomura T, Tajima Y (1982) Defined laboratory animals. In: Toxicology and Experimental Models. Advances in Pharmacology and Therapeutics II, Vol. 5 (Yoshida H, Hagihara Y, Ebashi S, eds] Oxford: Pergamon Press, pp 325-33
47. Öbrink KJ (1991) Basic research in physiology and pharmacology, some introductory remarks. In: Replacement, Reduction and Refinement: Present Possibilities and Future Prospects (Hendriksen CFM, Koëter HBWM, eds). Amsterdam: Elsevier, pp 79-84
48. Öbrink KJ, Rehbinder C (1993) The defined animal. Scandinavian Journal of Laboratory Animal Science 20, 5-9.
49. OECD (1992) Series on Principles of Good Laboratory Practice and Compliance Monitoring. Numbers 1-6. General Distribution OECD/GD(92) 32-37, Paris 1992
50. Perrot A, Canard G (1993) Environmental factors and effects on breeding performances and housing in small laboratory rodents: a technical report. Scandinavian Journal of Laboratory Animal Science 20, 61-8
51. Pfaff J (1974) Noise as an environmental problem in the animal house. Laboratory Animals 8, 347-54
52. Rehbinder CH (1994) Health monitoring. In: Handbook of Laboratory Animal Science, Vol. 1. Selection and Handling of Animals in Biomedical Research (Svendsen P, Hau J, eds). Florida: CRC Press Inc.
53. Rehbinder C, Baneux P, Forbes D, van Herck H, Nicklas W, Rugaya Z, Winkler G (1996) FELASA recommendations for the healthy monitoring of mouse, rat, hamster, gerbil, guineapig and rabbit experimental units. Laboratory Animals 30, 193-208
54. Rehbinder C, Öbrink KJ (1997) Laboratory animal science: a definition. In: Proceedings of the Sixth FELASA Symposium, 19-21 June 1996, Basel, Switzerland (O'Donoghue PN, ed). London: Royal Society Medicine Press, pp 144-5
55. Rehbinder C, Baneux P, van Herck H, Nicklas W, Ruguya Z, Winkler G (1988 ) FELASA recommendations for the health monitoring of breeding colonies and experimental units of cats, dogs and pigs. Laboratory Animals 32, 1-17
56. Reiter RJ (1986) Normal patterns of melatonin levels in the pineal gland and body fluids of humans and experimental animals. Journal of Neural Transmission Supplement 21, 35-54
57. Robinson M, Hart D, Pigott GH (1991) The effects of diet on the incidense of peridontitis in rats. Laboratory Animals 25, 247-53
58. Romero JA (1976) Influence of diurnal cycles on biochemical parameters of drug sensitivity: the pineal gland as a model. Federation Proceedings 35, 1157-61
59. Russell WMS, Burch RL (1992) The Principles of Humane Experimental Technique, 2nd edn. London: Methuen
60. Sales GB, Wilson KJ, Spencer KEV, Milligan SR (1988) Environmental ultrasound in laboratories and animal houses: a possible cause for welfare and use of laboratory animals. Laboratory Animals 22, 369-75
61. Stupfel M, Damiani P, Perramon A, Busnel MC, Gourlet V, Thierry H (1985) Ultradian and circadian respiratory rhythms in grouped small laboratory vertebrate species as a method to assess the effects of environmental challenges. Comparative Biochemistry and Physiology 80, 225-31
62. Voipio HM (1997) How do rats react to sound? Scandinavian Journal of Laboratory Animal Science 24 (suppl 1), 80
63. Wallen EP, Turek FW (1981) Photoperiodicity in the male albino laboratory rat. Nature 289, 402-4