Surgical margins, local recurrence and metastasis in soft tissue sarcomas: 559 surgically-treated patients from the Scandinavian Sarcoma Group Register

European Journal of Cancer

Volumn 36, Issue 6, 2000, Pages 710-716

  Trovik, C S ^a   Bauer, H C F ^b   Alvegard T A ^c   Anderson, H ^c   Blomqvist, C ^d   Berlin, Ö ^e   Gustafson, P ^c   Saeter G ^f   Walloe A ^g  

^a HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^f OSLO UNIVERSITY HOSPITAL   (Norway)

^g ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

Local recurrence; Metastasis; Multicentre study; Multivariate analysis; Soft tissue sarcoma; Surgical margins

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LIMB; MAJOR CLINICAL STUDY; MALE; METASTASIS; MULTICENTER STUDY; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROGNOSIS; RECURRENCE RISK; RISK FACTOR; SOFT TISSUE SARCOMA; SURVIVAL; TRUNK;

EID: 0034031488     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(99)00287-7     Document Type: Article

References (34)

1. Choong P.F., Gustafson P., Rydholm A. Size and timing of local recurrence predicts metastasis in soft tissue sarcoma. Growth rate index retrospectively analyzed in 134 patients. Acta. Orthop. Scand. 66:1995;147-152.
2. Gustafson P., Rööser B., Rydholm A. Is local recurrence of minor importance for metastases in soft tissue sarcoma? Cancer. 67:1991;2083-2086.
3. Rööser B., Gustafson P., Rydholm A. Is there no influence of local control on the rate of metastasis in high-grade soft tissue sarcoma? Cancer. 65:1990;1727-1729.
4. Williard W.C., Collin C., Casper E.S., Hajdu S.I., Brennan M.F. The changing role of amputation for soft tissue sarcoma of the extremity in adults. Surg. Gynecol. Obstet. 175:1992;389-396.
5. Williard W.C., Hajdu S.I., Casper E.S., Brennan M.F. Comparison of amputation with limb-sparing operations for adult soft tissue sarcoma of the extremity. Ann. Surg. 215:1992;269-275.
6. Gustafson P., Dreinhöfer K.E., Rydholm A. Metastasis-free survival after local recurrence of soft tissue sarcoma. J. Bone Joint Surg. 75B:1993;658-660.
7. Benjamin D.J. The efficacy of surgical treatment of cancer. Medical Hypotheses. 40:1993;129-138.
8. Gustafson P. Soft tissue sarcoma. Epidemiology and prognosis in 508 patients. Acta Orthop. Scand. 65(Suppl. 259):1994;1-31.
9. Yang J.C., Rosenberg S.A. Surgery for adult patients with soft tissue sarcomas. Semin. Oncol. 14:1989;289-296.
10. Harrison L.B., Franzese F., Gaynor J.J., Brennan M.F. Long-term results of a prospective randomized trial of adjuvant brachytherapy in the management of completely resected soft tissue sarcomas of the extremity and superficial trunk. Int. J. Radiat. Oncol. Biol. Phys. 27:1993;259-265.
11. Emrich L., Ruka W., Driscoll D., Karakousis C. The effect of local recurrence on survival time in adult high-grade soft-tissue sarcomas. J. Clin. Epidemiol. 42:1989;105-110.
12. Stotter A., A'Hearn R., Fisher C., Mott A.F., Fallowfield M.E., Westbury G. The influence of local recurrence of extremity soft tissue sarcoma on metastasis and survival. Cancer. 65:1990;1119-1129.
13. Lewis J.J., Leung D., Heslin M., Woodruff J.M., Brennan M. Association of local recurrence with subsequent survival in extremity soft tissue sarcoma. J. Clin. Oncol. 15:1997;646-652.
14. Trovik C.S., Bauer H.C.F. Local recurrence of soft tissue sarcoma, a risk factor for late metastases. 379 patients followed for 0.5-20 years. Acta Orthop. Scand. 65:1994;553-558.
15. Choong P.F., Gustafson P., Willen H.et al. Prognosis following locally recurrent soft-tissue sarcoma. A staging system based on primary and recurrent tumor characteristics. Int. J. Cancer. 60:1995;33-37.
16. Coindre J-M., Terrier P., Bui N.B.et al. Prognostic factors in adult patients with locally controlled soft tissue sarcoma. a study of 546 patients from the French Federation of Cancer Centers Sarcoma Group J. Clin. Oncol. 14:1996;869-877.
17. Pisters P.W., Leung D.H., Woodruff J., Shi W., Brennan M. Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities. J. Clin. Oncol. 14:1996;1679-1689.
18. Wiklund T.A., Alvegard T.A., Mouridsen H.T., Rydholm A., Blomqvist C.P. Marginal surgery and postoperative radiotherapy in soft tissue sarcomas. The Scandinavian Sarcoma Group experience. Eur. J. Cancer. 29A:1993;306-309.
19. Alvegård T.A., Sigurdsson H., Mouridsen H.et al. Adjuvant chemotherapy with doxorubicin in high-grade soft tissue sarcoma, a randomized trial of the Scandinavian Sarcoma Group. J. Clin. Oncol. 7:1989;1504-1513.
20. Solheim Ø, Alvegård TA, Berg NO, et al. Treatment program for soft sissue sarcoma (malignancy grades I-IV). SSG V, Regional Tumor Registry, Department of Oncology, University Hospital Lund, 1986.
21. Angervall L., Kindblom L-G. Principles of pathologic anatomic diagnosis and classification of soft tissue sarcomas. Clin. Orthop. 289:1993;9-18.
22. Enneking W.F., Spanier S.S., Godman N.A. A system for the surgical staging of musculoskeletal sarcoma. Clin. Orthop. 153:1980;106-120.
23. Kaplan E.L., Meier P. Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 53:1958;457-481.
24. Cox D.R. Regression models and life tables. J. R. Stat. Soc. 34B:1972;187-220.
25. Gaynor J.J., Tan C.C., Casper E.S.et al. Refinement of clinical pathologic staging for localized soft tissue sarcoma of the extremity. a study of 423 adults J. Clin. Oncol. 10:1992;1317-1329.
26. Kalbfleisch JD, Prentice RL. The Statistical Analysis of Failure Time Data. New York, Wiley & Sons, 1980, 119-142.
27. StataCorp. 1997. Stata Statistical Software: Release 5.0. College Station, Texas, USA, Stata Corporation.
28. Alho A., Alvegård T.A., Berlin Ö.et al. Surgical margin in soft tissue sarcoma. Acta Orthop. Scand. 60:1989;687-692.
29. Berlin Ö., Stener B., Angervall L., Kindblom L-G., Markhede G., Odén A. Surgery for soft-tissue sarcoma in the extremities. Acta. Orthop. Scand. 61:1990;475-486.
30. Alvegård T.A., Berg N.O. Histopathology peer rewiew of high-grade soft tissue sarcoma. the Scandinavian Sarcoma Group Experience J. Clin. Oncol. 7:1989;1845-1852.
31. Bauer H.C.F., Berlin Ö., Høie J.et al. Reasons for abstaining from radiotherapy after a poor surgical margin in soft tissue sarcoma - a SSG Register study. Acta. Orthop. Scand. 68(Suppl. 274):1997;68-69.
32. Ueda T., Yoshikawa H., Mori S.et al. Influence of local recurrence on the prognosis of soft-tissue sarcomas. J. Bone Joint Surg. 79B:1997;553-557.
33. Tanabe K.K., Pollock R.E., Ellis L.M., Murphy A., Sherman N., Romsdahl M.M. Influence of surgical margins on outcome in patients with preoperatively irradiated extremity soft tissue sarcomas. Cancer. 73:1994;1652-1659.
34. Li X.Q., Parkekh S.G., Rosenberg A.E., Mankin H.J. Assessing prognosis for high-grade soft-tissue sarcomas. search for a marker Ann. Surg. Oncol. 3:1996;550-557.