The pharmacologic mechanism by which inhaled epinephrine reduces airway obstruction in respiratory syncytial virus-associated bronchiolitis

Journal of Pediatrics

Volumn 136, Issue 5, 2000, Pages 699-700

  Barr, Frederick E ^a,b   Patel, Neal R ^a,b   Newth, Christopher J L ^a,b  

^a MONROE CARELL JR CHILDREN S HOSPITAL AT VANDERBILT   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; PROPAFENONE; PROPRANOLOL; SALBUTAMOL;

AIRWAY OBSTRUCTION; ALPHA ADRENERGIC STIMULATION; ARTICLE; BRONCHIOLITIS; CASE REPORT; DRUG MECHANISM; HUMAN; INFANT; MALE; NEBULIZATION; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SUPRAVENTRICULAR TACHYCARDIA; TREATMENT OUTCOME;

EID: 0034031340     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1067/mpd.2000.105358     Document Type: Article

References (9)

1. 1. Hammer J, Numa A, Newth CJL. Albuterol responsiveness in infants with respiratory failure caused by respiratory syncytial virus infection. J Pediatr 1995;127:485-90.
2. 2. Sanchez I, De Koster J, Powell RE, Wolstein R, Chernick V. Effect of racemic epinephrine and salbutamol on clinical score and pulmonary mechanics in infants with bronchiolitis. J Pediatr 1993;122:145-51.
3. 3. Kristjansson S, Lodrup Carlsen KC, Wennergen G, Strannegard IL, Carlsen KH. Nebulized racemic adrenaline in the treatment of acute bronchiolitis in infants and toddlers. Arch Dis Child 1993;69:650-4.
4. 4. Menon K, Sutcliffe T, Klassen TP. A randomized trial comparing the efficacy of epinephrine with salbutamol in the treatment of acute bronchiolitis. J Pediatr 1995;126:1004-7.
5. 5. Reijonen T, Korppi M, Pitkakangas S, Tenhola S, Remes K. The clinical efficacy of nebulized racemic epinephrine and albuterol in acute bronchiolitis. Arch Pediatr Adolesc Med 1995;149: 686-92.
6. 6. Wood DW, Downes JJ, Lecks HI. A clinical scoring system for the diagnosis of respiratory failure. Am J Dis Child 1972;123:227-8.
7. 7. Lenney W, Milner AD. Alpha and beta adrenergic stimulants in bronchiolitis and wheezy bronchiolitis in children under 18 months of age. Arch Dis Child 1978;53:707-9.
8. 8. Ramoska EA, Henretig F, Joffe M, Spiller HA. Propranolol treatment of albuterol poisoning in two asthmatic patients. Ann Emerg Med 1993;22:1474-6.
9. 9. Newth CJL, Amsler B, Richardson BP, Hammer J. The effects of bronchodilators on spontaneous ventilation and oxygen consumption in Rhesus monkeys. Pediatr Res 1997;42:157-62.