Transgenic studies in rats and mice on the osmotic regulation of vasopressin gene expression

Experimental Physiology

Volumn 85 S, Issue SPEC. ISS., 2000, Pages

  Murphy, David ^b   Xu, Jing ^a,b   Waller, Sarah ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; GENE EXPRESSION; HYPOTHALAMUS; MOUSE; NONHUMAN; OSMOREGULATION; RAT; REVIEW; TRANSGENE;

EID: 0034031143     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-445x.2000.tb00026.x     Document Type: Review

References (79)

1. ANG, H.-L., CARTER, D. A. & MURPHY, D. (1993). Neuron-specific and physiological regulation of bovine vasopressin transgenes in mice. EMBO Journal 12, 2397-2409.
2. ARIMA, H., KONDO, K., KAKIYA, S., NAGASAKI, H., YOKOI, H., YAMBE, Y., MURASE, T., IWASAKI, Y. & OISO, Y. (1999). Rapid and sensitive vasopressin heteronuclear RNA responses to changes in plasma osmolality. Journal of Neuroendocrinology 11, 337-341.
3. BERKOWITZ, L. A., RIABOWAL, K. T. & GILLMAN, M. Z. (1989). Multiple sequence elements of a single functional class are required for cAMP responsiveness of the mouse c-fos promoter. Molecular and Cellular Biology 9, 4272-4281.
4. BOERSMA, C. J. C., SONNEMANS, M. A. F. & VAN LEEWEN, F. W. (1993). Immunoelectron microscopic demonstration of oxytocin and vasopressin in pituicytes and in nerve terminals forming synaptoid contacts with pituicytes in the rat neural lobe. Brain Research 611, 117-129.
5. BROWNSTEIN, M., RUSSEL, J. & GAINER, H. (1980). Synthesis, transport and release of posterior pituitary hormones. Science 207, 373-387.
6. BURBACH, J. P. H., DE HOOP, M. J., SCHMALE, H., RICHTER, D., DE KLOET, E. R., TEN HAAF, J. A. & DE WIED, D. (1984). Differential responses to osmotic stress of vasopressin-neurophysin mRNA in hypothalamic nuclei. Neuroendocrinology 39, 582-584.
7. BURKE, Z. D., MORGAN, H., MURPHY, D. & CARTER, D. A. (1996). RNAs encoded by a 3.5 kb bovine vasopressin gene construct are targeted to the neurohypophysis of transgenic mice. Molecular Brain Research 42, 287-292.
8. CARRAZANA, E. J., PASIEKA, K. B. & MAJZOUB, J. A. (1988). The vasopressin mRNA poly(A) tract is unusually long and increases during stimulation of vasopressin gene expression in vivo. Molecular and Cellular Biology 8, 2267-2274.
9. CARTER, D. A. & MURPHY, D. (1989a). Cyclic nucleotide dynamics in the rat hypothalamus during osmotic stimulation: in vivo and in vitro studies. Brain Research 487, 350-356.
10. CARTER, D. A. & MURPHY, D. (1989b). Independent regulation of neuropeptide mRNA level and poly(A) tail length. Journal of Biological Chemistry 264, 6601-6603.
11. CARTER, D. A. & MURPHY, D. (1990). Regulation of c-fos and c-jun expression in the rat supraoptic nucleus. Molecular and Cellular Biology 10, 435-445.
12. CARTER, D. A. & MURPHY, D. (1991). Rapid changes in poly(A) tail length of vasopressin and oxytocin mRNAs form a common early component of neurohypophyseal peptide gene activation following physiological stimulation. Neuroendocrinology 53, 1-6.
13. CARTER, D. A., PARDY, K. & MURPHY, D. (1993). Regulation of vasopressin gene expression: changes in level, but not size, of VP mRNA following endocrine manipulations. Molecular and Cellular Biology 13, 87-95.
14. CHATURVEDI, C. M., ZHENG, Z., SHIMADA, K., CORNETT, L. E. & KOIKE, T. I. (1996). Changes in poly(A) tail length of arginine vasotocin messenger ribonucleic acid in the hypothalamus of water deprived chickens. General and Comparative Endocrinology 103, 316-322.
15. DAS GUPTA, J., GU, H., CHERNOKALSKAYA, E. & SCHOENBERG, D. R. (1998). Identification of two cis-acting elements that independently regulate the length of poly(A) on Xenopus albumin pre-mRNA. RNA 4, 766-776.
16. EMANUEL, R. L., GIRARD, D. M., THULL, D. L. & MAJZOUB, J. A. (1992). Regulated expression of vasopressin gene by cAMP and phorbol esters in primary rat fetal hypothalamic cultures. Molecular and Cellular Endocrinology 2, 29-36.
17. FEHN, M., LOHMANN, F., LUDECKE, D. K., RUDORFF, K. H. & SAEGER, W. (1998). Ganglioglioma of the neurohypophysis with secretion of vasopressin. Experimental Clinical Endocrinology Diabetes 106, 425-430.
18. FITZSIMMONS, M. D., ROBERTS, M. M. & ROBINSON, A. G. (1994). Control of posterior pituitary vasopressin content: implications for the control of the vasopressin gene. Endocrinology 134, 1874-1878.
19. FITZSIMMONS, M. D., ROBERTS, M. M., SHERMAN, T. G. & ROBINSON, A. G. (1992). Models of neurohypophyseal homeostasis. American Journal of Physiology 262, R1121-1130.
20. GAINER, H. & WRAY, S. (1994). Cellular and molecular biology of oxytocin and vasopressin. In The Physiology of Reproduction, ed. KNOBIL, E. & NEILL, J. D., pp. 1099-1129. Raven Press, New York.
21. GRANJEAUD, S., BERTUCCI, F. & JORDAN, B. R. (1999) Expression profiling: DNA arrays in many disguises. BioEssay 21, 781-790.
22. GRANT, F. D., REVENTOS, J., GORDON, J. W., KAWABATA, S., MILLER, M. & MAJZOUB, J. A. (1993). Expression of rat arginine vasopressin gene in transgenic mice. Molecular Endocrinology 7, 659-667.
23. HATTON, G.I. (1986). Plasticity in the hypothalamic magnocellulary neurosecretory system. Federation Proceedings 45, 2328-2333.
24. HERMAN, J. P., SCHAFER, M. K.-H., WATSON, S. J. & SHERMAN, T. G. (1991). In situ hybridisation analysis of arginine vasopressin gene transcription using intron specific probes. Molecular Endocrinology 5, 1447-1456.
25. IANNACCONE, P. M., TABORN, G. U., GARTON, R. L., CAPLICE, M. D. & BRENIN, D. R. (1994). Pluripotent embryonic stem cells from the rat are capable of producing chimeras. Developmental Biology 163, 288-292.
26. IANNACCONE, P. M., TABORN, G. U., GARTON, R. L., CAPLICE, M. D. & BRENIN, D. R. (1997). Pluripotent embryonic stem cells from the rat are capable of producing chimeras (erratum). Developmental Biology 185, 124-125.
27. IVELL, R. & BURBACH, J. P. H. (1991). The molecular biology of vasopressin and oxytocin genes. Journal of Neuroendocrinology 3, 583-586.
28. JANAKY, T., SZABO, P., KELE, Z., BALASPIRI, L., VARGA, C., GALFI, M., VECSERNYES, M., GASPAR, L., JUHASZ, A. & LASZLO, F. A. (1998). Identification of oxytocin and vasopressin from neurohypophyseal cell culture. Rapid Communications in Mass Spectrometry 12, 1765-1768.
29. JIRIKOWSKI, G. F., SANNA, P. P. & BLOOM, F. E. (1990). mRNA coding for oxytocin is present in axons of the hypothalamoneurohypophysial tract. Proceedings of the National Academy of Sciences of the USA 87, 7400-7404.
30. JIRIKOWSKI, G. F., SANNA, P. P., MACIEJEWSKI-LENOIR, D. & BLOOM, F. E. (1992). Reversal of diabetes insipidus in Brattleboro rats: intrahypothalamic injection of vasopressin mRNA. Science 255, 996-998.
31. LANDRY, M. & HOKFELT, T. (1998). Subcellular localization of preprogalanin messenger RNA in perykarya and axons of hypothalamo-posthypophyseal magnocellular neurons: and in situ hybridisation study. Neuroscience 84, 897-912.
32. LEHMAN, E., HANZE, J., PAUSCHINGER, M., GANTEN, D. & LANG, R. E. (1990). Vasopressin mRNA in the neurolobe of the pituitary. Neuroscience Letters 111, 170-175.
33. LEVY, A., LIGHTMAN, S. L., CARTER, D. A. & MURPHY, D. (1990). The origin and regulation of posterior pituitary vasopressin ribonucleic acid in osmotically stimulated rats. Journal of Neuroendocrinology 3, 329-334.
34. LIGHTMAN, S. L. & YOUNG, W. S. (1987). Vasopressin, oxytocin, dynorphin, enkephalin and corticotrophin releasing factor mRNA stimulation in the rat. Journal of Physiology 394, 23-39.
35. LUCKMAN, S. M. (1995). Stimulus-specific expression of inducible transcription factors in identified oxytocin neurons. In Oxytocin: Cellular and Molecular Approaches in Medicine and Research, ed. IVELL, R. & RUSSELL, J. A., pp. 37-48. Plenum Press, London
36. LUCKMAN, S. M. & COX, H. J. (1995). Expression of inducible cAMP early repressor (ICER) in magnocellular hypothalamic neurons. Molecular Brain Research 34, 231-238.
37. LUCKMAN, S. M., DYE, S. & COX, H. J. (1996). Induction of members of the Fos/Jun family of immediately-early genes in identified hypothalamic neurones: in vivo evidence for differential regulation. Neuroscience 73, 473-485.
38. MCCABE, J. T., LEHMAN, E., CHASTRETTE, N., HANZE, J., LANG, R. E., GANTEN, D. & PFAFF, D. W. (1990). Detection of vasopressin mRNA in the neurointermediate lobe of the rat pituitary. Molecular Brain Research 8, 325-329.
39. MACIEJEWSKI-LENOIR, D., JIRIKOWSKI, G. F., SANNA, P. P. & BLOOM, F. E. (1902). Reduction of exogenous vasopressin RNA poly(A) tail length increases its effectivenes in transiently correcting diabetes insipidus in the rat. Proceedings of the National Academy of Sciences of the USA 90, 1435-1439.
40. MELLSTROM, B., NARANJO, J. R., FOULKES, N. S., LAFARGA, M. & SASSONE-CORSI, P. (1993). Transcriptional responses to cAMP in brain: specific distribution and induction of CREM antagonists. Neuron 10, 655-665.
41. MOHR, E., FEHR, S. & RICHTER, D. (1991). Axonal transport of neuropeptide encoding mRNAs within the hypothalamo-hypophyseal tract of rats. EMBO Journal 10, 2419-2424.
42. MOHR, E., MORRIS, J. F. & RICHTER, D. (1995). Differential subcellular mRNA targeting: deletion of a single nucleotide prevents the transport to axons but not dendrites of rat hypothalamic magnocellular neurons. Proceedings of the National Academy of Sciences of the USA 92, 4377-4381.
43. MOHR, E. & RICHTER, D. (1990). Diversity of mRNAs in the axonal compartment of peptidergic neurons of the rat. European Journal of Neuroscience 4, 870-876.
44. MOHR, E., ZHOU, A., THORN, N. A. & RICHTER, D. (1990). Rats with physically disconnected hypothalamo-pituitary tracts no longer contain vasopressin-oxytocin gene transcripts in the posterior pituitary lobe. FEBS Letters 263, 332-336.
45. MURPHY, D., ANG, H.-L., ZENG, Q., HO, M.-Y., FUNKHOUSER, J. & CARTER, D. A. (1992). Neuropeptide gene expression in transgenic animals. Progress in Brain Research 92, 77-96.
46. MURPHY, D., BISHOP, A., RINDI, G., MURPHY, M. N., STAMP, G., HANSON, J., POLAK, J. & HOGAN, B. L. M. (1987). Mice transgenic for a vasopressin-SV40 hybrid oncogene develop tumors of the endocrine pancreas and the anterior pituitary: a possible model for human multiple endocrine neoplasia. American Journal of Pathology 129, 552-566.
47. MURPHY, D. & CARTER, D. A. (1990). Vasopressin gene expression in the rodent hypothalamus: transcriptional and post-transcriptional responses to physiological stimulation. Molecular Endocrinology 4, 1051-1059.
48. MURPHY, D. & CARTER, D. A. (1993). Transgenesis Techniques: Principles and Protocols. In Methods in Molecular Biology, vol. 18. Humana Press, Totowa, NJ, USA.
49. MURPHY, D., FUNKHOUSER, J., ANG, H.-L., FOO, N.-C. & CARTER, D. A. (1993). Extrahypothalamic expression of the vasopressin and oxytocin genes. Annals of the New York Academy of Sciences 689, 91-106.
50. MURPHY, D., LEVY, A., LIGHTMAN, S. & CARTER, D. A. (1989). Vasopressin RNA in the neural lobe of the pituitary: dramatic accumulation in response to salt-loading. Proceedings of the National Academy of Sciences of the USA 86, 9002-9005.
51. PARDY, K., ADAN, R. A. H., CARTER, D. A., SEAH, V., BURBACH, J. P. H. & MURPHY, D. (1992). The identification of a cis-acting element involved in the cyclic 3′,5′-adenosine monophosphate regulation of bovine vasopressin gene expression. Journal of Biological Chemistry 267, 21746-21752.
52. PU, L.-P., VAN LEEUWEN, F. W., TRACER, H., SONNEMANS, M. A. F. & LOH, V. P. (1995). Localisation of vasopressin mRNA and immuno-reactivity in pituicytes of pituitary stalk-transected rats after osmotic stimulation. Proceedings of the National Academy of Sciences of the USA 92, 10653-10657.
53. RAO, M. N., CHERNOKALSKAYA, E. & SCHOENBERG, D. R. (1996). Regulated nuclear polyadenylation of Xenopus albumin pre-mRNA. Nucleic Acid Research 24, 4078-4083.
54. REEVES, W. B. & ANDREOLI, T. E. (1992). The posterior pituitary and water metabolism. In Williams Textbook of Endocrinology, ed. WILSON, J. D. & FOSTER, D. W., pp. 311-356. W. B. Saunders, Philadelphia.
55. RENAUD, L .P. & BOURQUE, C. W. (1991). Neurophysiology and neuropharmacology of hypothalamic magnocellular neurons secreting vasopressin. Progress in Neurobiology 36, 131-169.
56. SCHMALE, H. & RICHTER, D. (1984). Single base deletion in the vasoC pressin gene is the cause of diabetes insipidus in Brattleboro rats. Nature 308, 705-709.
57. SHERMAN, T. G., CIVELLI, O., DOUGLASS, J., HERBERT, E., BURKE, S. & WATSON, S. J. (1986a). Hypothalamic dynorphin and vasopressin mRNA expression in normal and Brattleboro rats. Federation Proceedings 45, 2323-2327.
58. SHERMAN, T. G., CIVELLI, O., DOUGLASS, J., HERBERT, E. & WATSON, S. J. (1986b). Coordinate expression of hypothalamic prodynorphin and pro-vasopressin mRNAs with osmotic stimulation. Neuroendocrinology 44, 222-228.
59. SHERMAN, T. G., DAY, R., CIVELLI, O., DOUGLAS, J., HERBERT, E., AKIL, H. & WATSON, S. J. (1988). Regulation of hypothalamic magnocellular neuropeptides and their mRNAs in the Brattleboro rat: coordinate responses to further osmotic challenge. Journal of Neuroscience 8, 3785-3796.
60. SHERMAN, T. G., MCKELVY, J. F. & WATSON, S. J. (1986c). Vasopressin mRNA regulation in individual hypothalamic nuclei: a northern and in situ hybridisation study. Journal of Neuroscience 6, 1685-1694.
61. SKUTELLA, T., PROBST, J. C., BLANCO, E. & JIRIKOWSKI, G. F. (1994). Localization of tyrosine hydroxylase mRNA in the axons of the hypothalamo-neurohypophyseal system. Molecular Brain Research 23, 179-184.
62. SKUTELLA, T., PROBST, J. C. & JIRIKOWSKI, G. F. (1995). c-fos mRNA is present in axons of the hypothalamo-neurohypophyseal system of the rat. Cellular and Molecular Biology 41, 793-798.
63. SLADEK, C. D. & GALLAGHER, M. J. (1993). The stimulation of vasopressin gene expression in cultured hypothalamic neurons by cyclic adenosine 3′,5′-monophosphate is reversible. Endocrinology 133, 1320-1330.
64. SLADEK, C. D. & OLSCHOWSKA, J. A. (1994). Dehydration induces c-fos, but not increased vasopressin mRNA in the supraoptic nucleus of aged rats. Brain Research 652, 207-215.
65. STEFANEANU, L., RINDI, G., HORVATH, E., MURPHY, D., POLAK, J. M. & KOVACS, K. (1992). Morphology of adenohypophyseal tumors in mice transgenic for vasopressin-SV40 hybrid oncogene. Endocrinology 130, 1780-1788.
66. SUEMARA, S., HASHIMOTO, K., OGASA, T., TAKAO, T., OTA, Z., HIRAKAWA, M. & KAWATA, M. (1990). Effects of hyperosmotic stimulation and adrenalectomy on vasopressin levels in the paraventricular and supraoptic nuclei of the hypothalamus: in situ hybridisation histochemical analysis using a synthetic oligonueleotide probe. Acta Medico Okayama 44, 233-241.
67. TIEDGK, H., ZHOU, A., THORN, N. A. & BKOSIUS, J. (1993). Transport of BCl RNA in hypothalamo-neurohypophseal axons. Journal of Neuroscience 13, 4214-4219.
68. TREMBLEAU, A., MORALES, M. & BLOOM, F. E. (1994). Aggregation of vasopressin mRNA in a subset of axonal swellings of the median eminence and posterior pituitary: light and electron microscopic evidence. Journal of Neuroscience 14, 39-53.
69. TREMBLEAU, A., MORALES, M. & BLOOM, F. E. (1990). Differential compartmentalisation of vasopressin messenger RNA and neuropeptide within the rat hypothalamo-neurohypophyseal axonal tract: light and electron microscopic evidence. Neuroscience 70, 113-125.
70. VALTIN, H. & SCHROEDER, H. A. (1964). Familial hypothalamic diabetes insipidus in rats (Brattleboro strain). American Journal of Physiology 206, 425-430.
71. VERBEEK, M. A. E., ADAN, R. A. H. & BURBACH, J. P. H. (1991). Vasopressin gene expression is stimulated by cyclic AMP in homologous and heterologous expression systems. FEBS Letters 272, 89-93.
72. WALLER, S., CARTER, D. A. & MURPHY, D. (19915). Regulation of the extent of polyadenylation of vasopressin and growth hormone mRNAs in response to physiological stimuli. Regulatory Peptides 45, 37-41.
73. WALLER, S., FAIRHALL, K. M., XU, J., ROBINSON, I. C. A. F. & MURPHY, D. (1996). Neurohypophyseal and fluid homeostasis in transgenic rats expressing a tagged rat vasopressin prepropeptide in hypothalamic neurons. Endocrinology 137, 5068-5077.
74. WICKENS, M. (1990). In the beginning is the end: regulation of poly(A) addition and removal during early development. Trends in Biochemical Sciences 15, 320-324.
75. YOUNG, W. S. (1989). Levels of transcripts encoding a member of the protein kinase C family in the paraventricular and supraoptic nuclei are increased by hyperosmolality. Journal of Neuroendocrinology 1, 1-4.
76. YOUNG, W. S., SHEPARD, E. A. & BURCH, R. M. (1987). Plasma hyperosmolality increases G protein and 3′,5′-cyclic adenosine monophosphate synthesis in the paraventricular and supraoptic nuclei. Molecular Endocrinology 1, 884-888.
77. ZENG, Q., CARTER, D. A. & MURPHY, D. (1994a). Cell specific expression of a vasopressin transgene in rats. Journal of Neuroendocrinology 6, 469-477.
78. ZENG, Q., FOO, K-C., FUNKHOUSER, J. M., CARTER, D. A. & MURPHY, D. (1994b). Expression of a rat vasopressin transgene in rat testes. Journal of Reproduction and Fertility 102, 471-481.
79. ZINGG, H. H., LEFEBVRE, D. & ALMAZAN, G. (1986). Regulation of vasopressin gene expression in hypothalamic neurons. Journal of Biological Chemistry 261, 12956-12959.