Interpretation guidelines of DNA histograms from tissue sections of breast cancer

Anticancer Research

Volumn 20, Issue 1 B, 2000, Pages 547-551

  Aaltonen, Markku ^a   Kuopio, Teijo ^b   Laine, Juhana ^a   Alanen, Kalle ^a   Juhola, Matti ^b   Collan, Yrjö ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b JYVÄSKYLÄ CENTRAL HOSPITAL   (Finland)

Author keywords

Breast cancer; DNA image cytometry; Flow cytometry; Histopathology

Indexed keywords

CELL NUCLEUS DNA; DNA;

ANEUPLOIDY; ARTICLE; BREAST CANCER; CANCER GRADING; FLOW CYTOMETRY; HISTOGRAM; HUMAN; HUMAN TISSUE; IMAGE CYTOMETRY; MAJOR CLINICAL STUDY; PRACTICE GUIDELINE; PRIORITY JOURNAL;

ANEUPLOIDY; BREAST NEOPLASMS; CLONE CELLS; DNA, NEOPLASM; EVALUATION STUDIES; FEMALE; FLOW CYTOMETRY; GUIDELINES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; OBSERVER VARIATION; PARAFFIN EMBEDDING; STAINING AND LABELING;

EID: 0034029742     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Chetty R, O'Leary J and Gatter K: Immunocytochemistry as a diagnostic tool. Curr Diag Pathol 2: 38-45, 1995.
2. Böcking A, Giroud F and Reith A: Consensus report of the European Society for Analytical Cellular Pathology Task Force on Standardization of Diagnostic DNA Image Cytometry. Anal Quant Cytol Histol 17: 1-7, 1995.
3. Hedley DW, Friedlander ML, Taylor IW Rugg CA and Musgrove EA: Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry. J Histochem Cytochem 31: 1333-1335, 1983.
4. Vindeloøv LL, Christenssen IJ and Nissen NI: A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3: 323-327, 1983.
5. Joensuu H, Alanen K, Falkmer UG, Klemi P, Nordling S, Remvikos Y and Toikkanen S: Effect of DNA ploidy classification on prognosis in breast cancer. Int J Cancer 52: 701-706, 1992.
6. Gaub J, Auer GU and Zetterberg A: Quantitative cytochemical aspects of a combined Feulgen naphtol yellow S staining procedure for the simultaneous determination of nuclear and cytoplasmic protein and DNA in mammalian cells. Exp Cell Res 92: 902-908, 1975.
7. Collan Y: General principles of grading lesions in diagnostic histopathology. Path Res Pract 185: 539-543, 1989b.
8. Galen RS and Gambin SA: Beyond normality: The predictive value and efficiency of medical diagnoses. New York Wiley 1975.
9. Harvey JM, Sterrett GF, Berryman IL and Hopley JH: Nuclear DNA content of human breast carcinoma: A comparison of results obtained by microspectrophotometry and flow cytometry of paraffin embedded tissue. Pathology 25: 261-267, 1993.
10. Lanigan D, McLean PA, Curran B and Leader M: Comparison of flow and static image cytometry in the determination of ploidy. Clin Pathol 46: 135-139, 1993.
11. Sapi Z, Hendricks JB, Pharis PG and Wilkinson EJ: Tissue section image analysis of breast neoplasms. Am J Clin Pathol 99: 714-720, 1993.
12. Ottesen GL, Christensen IJ, Larsen JK, Larsen J, Christitensen LJ, Baldetorp B, Linden T, Hansen B and Andersen JA: DNA ploidy analysis in breast carcinoma. Comparison of unfixed and fixed tissue analyzed by image and flow cytometry. Anal Quant Cytol Histol 19: 413-422, 1997.
13. Schimmelpenning H, Hamper K, Falkmer UG, Caselitz J, Seifert G and Auer GU: Methodologic aspects of DNA assessment by means of image cytometry in tumors of the salivary glands. Anal Quant Cytol Histol 11: 379-383, 1989.
14. Rondez R, Yoshizaki C and Pirozynski W: Determination of nuclear DNA content and hormone receptors in breast cancer by the CAS 100 cell analysis system as related to morphologic grade and biochemical results. Anal Quant Cytol Histol 13: 233-245, 1991.
15. Lee AKC, Dugan J, Hamilton WM Cook L, Heatley G, Kamat B and Silverman ML: Quantitative DNA analysis in breast carcinomas: A comparison between image analysis and flow cytometry. Mod Pathol 4: 178-182, 1991.
16. Soørensen FB and Erlandsen M: Intralesional and metastatic heterogeineity in malignant melanomas demonstrated by stereologic estimates of nuclear volume. Lab Invest 62: 646-654, 1990.
17. Wilbur DC, Zakowski MF, Kosciol CM, Sojda DF and Pastuszak: DNA ploidy in breast lesions. Anal Quant Cytol Histol 12: 28-34, 1990.
18. Troncoso P, Dytch HE, Bibbo M, Wied GL and Dawson PJ: The significance of DNA measurements in a histologically defined subset of infiltrating ductal carcinomas of the breast with long-term followup. Anal Quant Cytol Histol 11: 166-172, 1989.
19. Auer GU, Askensten U, Erhardt K, Fallenius A and Zetterberg A: Comparison between slide and flow cytophotometric DNA measurements in breast tumors. Anal Quant Cytol Histol 9: 138-146, 1987.
20. Fallenius AG, Auer GU and Carstensen JM: Prognostic significance of DNA measurements in 409 consecutive breast cancer patients. Cancer 62: 331-341, 1988.
21. Auer GU, Caspersson TO and Wallgren AS: DNA content and survival in mammary carcinoma. Anal Quant Cytol Histol 2: 161-165, 1980.
22. Siitonen S, Kallioniemi OP, Helin HJ and JJ Isola: Prognostic value of cells with more than 5c DNA content in node-negative breast cancer as determinated by image cytometry from tissue sections. Hum Pathol 24: 1348-1353, 1993.
23. Azua J, Romeo P, Serrano M, Tello DM and Azua Jr.: Prognostic value from DNA quantification by static cytometry in breast cancer. Anal Quant Cytol Histol 19: 80-86, 1997.
24. Talve L, Collan Y and Ekfors T: Primary malignant melanoma of the skin, relationship of nuclear DNA content, nuclear morphometric variables, Clark level and tumor thicness. Anal Quant Cytol Histol 8: 1-3, 1996.
25. Bauer HCF, Kreicbergs A and Tribukait B: DNA microspectrophotometry of bone sarcomas in tissue sections as compared to imprint and flow DNA analysis. Cytometry 7: 544-550, 1986.
26. Williams RA, Baak JPA, Meijer GA and IG Charlton: Exploring the possibility of DNA ploidy measurements in tissue sections using liver as a model. Anal Quant Cytol Histol 19: 19-29, 1997.
27. Klapperstuck T and Wohlrab W: DNA image cytometry on sections as compared with image cytometry on smears and flow cytometry in melanoma. Cytometry 25: 82-89, 1996.
28. Kujari HP and Collan YU: Section thicness and mitotic counts in ovarian mucinous carcinoma. Methodological study with scanning confocal microscopy. Anal Cell Pathol 10: 253-262, 1996.
29. Gschwendtner A and Mairinger T: How thick is your section? The, influence of section thickness on DNA-cytometry on histological sections. Anal Cell Pathol 9: 29-37, 1995.
30. Bacus JW and Bacus JV: A method of correcting DNA ploidy measurements in tissue sections. Mod Pathol 7; 652-665, 1994.