Differential expression of genes by tumor cells of a low or a high malignancy phenotype: The case of murine and human Ly-6 proteins

Journal of Cellular Biochemistry

Volumn 77, Issue , 2000, Pages 61-66

  Witz, Isaac P ^a,b  

^a TEL AVIV UNIVERSITY   (Israel)

^b Incumbent of the David Furman Chair in Immunobiology of Cancer ^*  (Israel)

Author keywords

Gene expression; Ly 6; Tumor progression; UPAR

Indexed keywords

CELL ADHESION MOLECULE; GLYCOPROTEIN; LY ANTIGEN; LY6D PROTEIN, HUMAN; M PROTEIN; PROTEIN LY 6; UNCLASSIFIED DRUG; UROKINASE;

ANIMAL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOUSE; NEOPLASM; PATHOLOGY; REVIEW; CANCER GROWTH; CELL SELECTION; DISEASE ASSOCIATION; GENE CONTROL; GENE EXPRESSION; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, LY; CELL ADHESION MOLECULES; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; MICE; NEOPLASMS;

ALIA; MURINAE;

EID: 0034029490     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(2000)77:34+<61::AID-JCB11>3.0.CO;2-S     Document Type: Review

References (18)

1. Andreasen PA, Kjøller L, Christensen L, Duffy MJ. 1997. The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 72:1-22.
2. Ben-Baruch Langer A, Emmanuel N, Even J, Fridman WH, Gohar O, Gonen B, Katz B-Z, Ran M, Smorodinsky NI, Witz IP. 1992. Phenotypic properties of 3T3 cells transformed in vitro with polyoma virus and passaged once in syngeneic animals. Immunobiology 185:281-291.
3. Brakenhoff RH, Gerretsen M, Knippels PMC, Van Dijk M, Van Essen H, Olde Weghuis D, Sinke RJ, Snow GB, Van Dongen GAMS. 1995. The human E48 antigen, highly homologous with the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion. J Cell Biol 129:1677-1689.
4. Cohn MA, Kramerov D, Hulgaard EF, Lukanidin EM. 1997. The differentiation antigen Ly-6E.1 is expressed in mouse metastatic tumor cell lines. FEBS Lett 403:181-185.
5. Croxtall JD, Jamil A, Ayub M, Colletta AA, White JO. 1992. TGF-β stimulation of endometrial and breast-cancer cell growth. Int J Cancer 50:822-827.
6. 2 in patients with head and neck cancer. Clin Cancer Res 1:277-286.
7. De Flora A, Morelli A, Frascio M, Corte G, Curti B, Galliano M, Gozzer C, Minchiotti L, Mareni C, Gaetani G. 1977. Radioimmunoassay and chemical properties of glucose-6-phosphate dehydrogenase and of a specific NADP(H)-binding protein (FX) from human erythrocytes. Biochim Biophys Acta 500:109-123.
8. Eshel R, Firon M, Katz B-Z, Sagi-Assif O, Aviram H, Witz IP. 1995. Microenvironmental factors regulate Ly-6 A/E expression on PyV-transformed BALB/c 3T3 cells. Immunol Lett 44:209-212.
9. Fidler IJ. 1995. Modulation of the organ microenvironment for the treatment of cancer metastasis. J Natl Cancer Inst 84:1588-1592.
10. Fidler U, Kitadai Y, Takahashi Y, Ellis LM. 1996. Molecular determinants of human colon cancer metastasis. In: Tahara E, Sugimachi K, Dohara T, editors. Recent advances in gastroenterological carcinogenesis. Vol 1. Bologna: Monduzzi Editore. p 3-9.
11. Gumley TP, McKenzie IF, Sandrin HS. 1995. Tissue expression, structure and function of the murine Ly-6 family of molecules. Immunol Cell Biol 73:277-296.
12. Hakomori S-I. 1996. Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism. Cancer Res 56:5309-5318.
13. Halachmi E, Witz IP. 1989. Differential tumorigenicity of 3T3 cells transformed in-vitro with Polyoma virus and the in-vivo selection for high tumorigenicity. Cancer Res 49:2383-2389.
14. Katz B-Z, Eshel R, Sagi-Assif O, Witz IP. 1994. An association between high Ly-6A/E expression on tumor cells and a highly malignant phenotype. Int J Cancer 59:684-691.
15. Katz B-Z, Ishai-Michaeli R, Zusman T, Vlodavsky I, Witz IP. 1994-95. Lung colonization by and heparanase activity in in-vitro transformed 3T3 cells rendered highly tumorigenic by an in-vivo passage. Invasion Metast 14: 276-289.
16. Kibbey MC, Grant DS, Kleinman HK. 1992. Role of the SIKVAV site of laminin in promotion of angiogenesis and tumor growth: an in vivo Matrigel model. J Natl Cancer Inst 84:1633-1638.
17. Kimura Y, Furuhata T, Urano T, Hirata K, Nakamura Y, Tokino T. 1997. Genomic structure and chromosomal localization of GML (GPI-anchored molecule-like protein), a gene induced by p53. Genomics 41:477-480.
18. Kinzler KW, Vogelstein B. 1996. Lessons from hereditary colorectal cancer. Cell 87:159-170.