메뉴 건너뛰기




Volumn 19, Issue 3, 2000, Pages 364-368

Inhibitory effects of tranilast on the proliferation and functions of human pterygium-derived fibroblasts

Author keywords

Chemotaxis; Collagen gel contraction; Collagen synthesis; Fibroblasts; Proliferation; Pterygium; Tranilast

Indexed keywords

ANTIALLERGIC AGENT; TRANILAST;

EID: 0034028237     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003226-200005000-00021     Document Type: Article
Times cited : (27)

References (21)
  • 1
    • 0017180544 scopus 로고
    • Pharmacological properties of N-(3′,4′-dimethoxycinnamoyl)anthranilic acid (N-5′), a new anti-atopic agent
    • Azuma H, Banno K, Yoshimura T. Pharmacological properties of N-(3′,4′-dimethoxycinnamoyl)anthranilic acid (N-5′), a new anti-atopic agent. Br J Pharmacol 1976;58:483-8.
    • (1976) Br J Pharmacol , vol.58 , pp. 483-488
    • Azuma, H.1    Banno, K.2    Yoshimura, T.3
  • 2
    • 84886609137 scopus 로고
    • Inhibition of hypersensitivity reactions by a new drug, N-(3′,4′-dimethoxycinnamoyl)anthranilic acid (N-5′)
    • Koda A, Nagai H, Watanabe S, Yanagihara Y, Sakamoto K. Inhibition of hypersensitivity reactions by a new drug, N-(3′,4′-dimethoxycinnamoyl)anthranilic acid (N-5′). J Allergy Clin Immunol 1976;57: 396-407.
    • (1976) J Allergy Clin Immunol , vol.57 , pp. 396-407
    • Koda, A.1    Nagai, H.2    Watanabe, S.3    Yanagihara, Y.4    Sakamoto, K.5
  • 3
    • 0032425688 scopus 로고    scopus 로고
    • Tranilast: A new application in the cardiovascular field as an antiproliferative drug
    • Isaji M, Miyata H, Ajisawa Y. Tranilast: a new application in the cardiovascular field as an antiproliferative drug. Cardiovasc Drug Rev 1998;16:288-99.
    • (1998) Cardiovasc Drug Rev , vol.16 , pp. 288-299
    • Isaji, M.1    Miyata, H.2    Ajisawa, Y.3
  • 4
    • 0023153785 scopus 로고
    • Selective inhibition of collagen accumulation by W-(3,4-dimethoxycinnamoyl)anthranilic acid (N-5′) in granulation tissue
    • Isaji M, Nakajoh M, Naito J. Selective inhibition of collagen accumulation by W-(3,4-dimethoxycinnamoyl)anthranilic acid (N-5′) in granulation tissue. Biochem Pharmacol 1987;36:469-74.
    • (1987) Biochem Pharmacol , vol.36 , pp. 469-474
    • Isaji, M.1    Nakajoh, M.2    Naito, J.3
  • 5
    • 0011829319 scopus 로고
    • Inhibition by tranilast of collagen accumulation in hypersensitive granulomatous inflammation in vivo and of morphological changes and functions of fibroblasts in vitro
    • Isaji M, Aruga N. Naito J, Miyata H. Inhibition by tranilast of collagen accumulation in hypersensitive granulomatous inflammation in vivo and of morphological changes and functions of fibroblasts in vitro. Life Sci 1994;55:PL287-92.
    • (1994) Life Sci , vol.55
    • Isaji, M.1    Aruga, N.2    Naito, J.3    Miyata, H.4
  • 6
    • 0002421165 scopus 로고
    • Suppressive effects of tranilast (TN) on human mononuclear cells
    • Yanagi T, Watanabe M, Fukuda S, Tsuji Y. Suppressive effects of tranilast (TN) on human mononuclear cells. Jpn J Inflammation 1987; 7:169-73.
    • (1987) Jpn J Inflammation , vol.7 , pp. 169-173
    • Yanagi, T.1    Watanabe, M.2    Fukuda, S.3    Tsuji, Y.4
  • 7
    • 0026452457 scopus 로고
    • The mechanism involved in the inhibitory action of tranilast on collagen biosynthesis of keloid fibroblasts
    • Suzawa H, Kikuchi S, Arai N, Koda A. The mechanism involved in the inhibitory action of tranilast on collagen biosynthesis of keloid fibroblasts. Jpn J Pharmacol 1992;60:91-6.
    • (1992) Jpn J Pharmacol , vol.60 , pp. 91-96
    • Suzawa, H.1    Kikuchi, S.2    Arai, N.3    Koda, A.4
  • 8
    • 0028341154 scopus 로고
    • Prominent inhibitory effects of tranilast on migration and proliferation of collagen synthesis by vascular smooth muscle cells
    • Tanaka K, Honda M, Kuramochi T, Morioka S. Prominent inhibitory effects of tranilast on migration and proliferation of collagen synthesis by vascular smooth muscle cells. Atherosclerosis 1994;107:179-85.
    • (1994) Atherosclerosis , vol.107 , pp. 179-185
    • Tanaka, K.1    Honda, M.2    Kuramochi, T.3    Morioka, S.4
  • 9
    • 0029870944 scopus 로고    scopus 로고
    • Tranilast suppresses intimai hyperplasia in the balloon injury model and cuff treatment model in rabbits
    • Fukuyama J, Ichikawa K, Miyazawa K, Hamano S, Shibata N, Ujiie A. Tranilast suppresses intimai hyperplasia in the balloon injury model and cuff treatment model in rabbits. Jpn J Pharmacol 1996;70:321-7.
    • (1996) Jpn J Pharmacol , vol.70 , pp. 321-327
    • Fukuyama, J.1    Ichikawa, K.2    Miyazawa, K.3    Hamano, S.4    Shibata, N.5    Ujiie, A.6
  • 10
    • 0030844133 scopus 로고    scopus 로고
    • Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells in vitro and angiogenesis in vivo
    • Isaji M, Miyata H, Ajisawa Y, Takehana Y, Yoshimura N. Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells in vitro and angiogenesis in vivo. Br J Pharmacol 1997;122:1061-6.
    • (1997) Br J Pharmacol , vol.122 , pp. 1061-1066
    • Isaji, M.1    Miyata, H.2    Ajisawa, Y.3    Takehana, Y.4    Yoshimura, N.5
  • 11
    • 18144450314 scopus 로고    scopus 로고
    • Inhibition by tranilast of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF)-induced increase in vascular permeability in rats
    • Isaji M, Miyata H, Ajisawa Y, Yoshimura N. Inhibition by tranilast of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF)-induced increase in vascular permeability in rats. Life Sci 1998;63:PL71-4.
    • (1998) Life Sci , vol.63
    • Isaji, M.1    Miyata, H.2    Ajisawa, Y.3    Yoshimura, N.4
  • 12
    • 26144467793 scopus 로고    scopus 로고
    • Inhibitory effects of tranilast on proliferative reactions, angiogenesis, and contraction of fibrotic tissue
    • Isaji M, Miyata H, Ajisawa Y, Yoshimura N. Inhibitory effects of tranilast on proliferative reactions, angiogenesis, and contraction of fibrotic tissue [Abstract]. Invest Ophthalmol Vis Sci 1997;38(suppl 2):S753.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , Issue.SUPPL. 2
    • Isaji, M.1    Miyata, H.2    Ajisawa, Y.3    Yoshimura, N.4
  • 13
    • 0024847787 scopus 로고
    • Pathogenesis of pterygium
    • Hill JC, Maske R. Pathogenesis of pterygium. Eye 1989;3:218-26.
    • (1989) Eye , vol.3 , pp. 218-226
    • Hill, J.C.1    Maske, R.2
  • 16
    • 0015228599 scopus 로고
    • Use of a mixture of proteinase-free collagenase for the specific assay of radioactive collagen in the presence of other proteins
    • Peterkofsky B, Diegelmann R. Use of a mixture of proteinase-free collagenase for the specific assay of radioactive collagen in the presence of other proteins. Biochemistry 1971;10:988-93.
    • (1971) Biochemistry , vol.10 , pp. 988-993
    • Peterkofsky, B.1    Diegelmann, R.2
  • 17
    • 0030721608 scopus 로고    scopus 로고
    • P53 expression in altered limbal basal cells of pingueculae, pterygia, and limbal tumors
    • Dushku N, Reid TW. P53 expression in altered limbal basal cells of pingueculae, pterygia, and limbal tumors. Curr Eye Res 1997;16: 1179-92.
    • (1997) Curr Eye Res , vol.16 , pp. 1179-1192
    • Dushku, N.1    Reid, T.W.2
  • 18
    • 0343425864 scopus 로고    scopus 로고
    • Effect of tranilast on corneal haze after photorefractive keratectomy
    • Okamoto S. Effect of tranilast on corneal haze after photorefractive keratectomy. Atarashii Gannka (J Eye) 1997;14:239-43.
    • (1997) Atarashii Gannka (J Eye) , vol.14 , pp. 239-243
    • Okamoto, S.1
  • 19
    • 0029559386 scopus 로고
    • Single intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery
    • Cardillo JA, Alves MR, Ambrosio LE, Poterio MB, Jose NK. Single intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery. Ophthalmology 1995; 102:1949-52.
    • (1995) Ophthalmology , vol.102 , pp. 1949-1952
    • Cardillo, J.A.1    Alves, M.R.2    Ambrosio, L.E.3    Poterio, M.B.4    Jose, N.K.5
  • 20
    • 0343425866 scopus 로고
    • Clinical evaluation of tranilast ophthalmic solution in allergic conjunctivitis and vernal conjunctivitis by a multi-center double-blind comparative study: Double-blind comparative study with placebo
    • Yuasa T, Shimizu Y, Kogure F, Mikuni I, Saiga T, Ogawa N. Clinical evaluation of tranilast ophthalmic solution in allergic conjunctivitis and vernal conjunctivitis by a multi-center double-blind comparative study: double-blind comparative study with placebo. J Clin Ther Med 1993;9:53-67.
    • (1993) J Clin Ther Med , vol.9 , pp. 53-67
    • Yuasa, T.1    Shimizu, Y.2    Kogure, F.3    Mikuni, I.4    Saiga, T.5    Ogawa, N.6
  • 21
    • 0028361831 scopus 로고
    • Fibroblasts isolated from human pterygium exhibit transformed cell characteristics
    • Chen J-K, Tsai RJ-F, Lin S-S. Fibroblasts isolated from human pterygium exhibit transformed cell characteristics. In Vitro Cell Dev Biol 1993;30A:243-8.
    • (1993) In Vitro Cell Dev Biol , vol.30 A , pp. 243-248
    • Chen, J.-K.1    Tsai, R.-F.2    Lin, S.-S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.