Solution synthesis and biological activity of human pleiotrophin, a novel heparin-binding neurotrophic factor consisting of 136 amino acid residues with five disulfide bonds

Journal of Peptide Research

Volumn 55, Issue 5, 2000, Pages 384-397

  Inui, T ^a   Nakao, M ^a   Nishio, H ^a   Nishiuchi, Y ^a   Kojima, S ^b   Muramatsu, T ^c   Kimura, T ^a  

^a Protein Research Foundation   (Japan)

^b RIKEN TSUKUBA INSTITUTE   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Disulfide structure; Human pleiotrophin; Powerful solvent system; Segment condensation; Solution synthesis

Indexed keywords

AMINO ACID; HEPARIN; PLEIOTROPHIN;

AMINO ACID ANALYSIS; ARTICLE; CHEMICAL STRUCTURE; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; THIN LAYER CHROMATOGRAPHY;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BRAIN; CARRIER PROTEINS; CELLS, CULTURED; CYTOKINES; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; PEPTIDE BIOSYNTHESIS; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLASMINOGEN ACTIVATORS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS;

EID: 0034028190     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2000.00703.x     Document Type: Article

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