(+)Amphetamine-stimulus generalization to an herbal ephedrine product

Pharmacology Biochemistry and Behavior

Volumn 65, Issue 4, 2000, Pages 655-658

  Glennon, Richard A ^a   Young, Richard ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Amphetamine; Caffeine; Drug abuse; Ephedrine; Herbal dietary supplements; Stimulants

Indexed keywords

AMPHETAMINE; CAFFEINE; EPHEDRINE; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG ABUSE; DRUG EFFECT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STIMULUS GENERALIZATION;

ANIMALS; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; DEXTROAMPHETAMINE; DISCRIMINATION (PSYCHOLOGY); EPHEDRINE; GENERALIZATION, STIMULUS; INJECTIONS, INTRAPERITONEAL; MALE; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0034026259     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(99)00238-5     Document Type: Article

References (15)

1. Cowley, G.: Herbal warning. Newsweek May 6, 1996:60-68.
2. Fairchild M.D., Alles G.A. The central locomotor stimulatory activity and acute toxicity of ephedrine and norephedrine isomers in mice. J. Pharmacol. Exp. Ther. 58:1967;135-139.
3. Federal Register Dietary supplements containing ephedrine alkaloids. Fed. Reg. 62:1997;30677-30724.
4. Finney D. Probit analysis. 1952;Cambridge University Press, London.
5. Furuya I., Watanabe S. Discriminative stimulus properties of ephedra herb (Ephedra sinica) in rats. Jpn. J. Psychopharmacol. 13:1993;33-38.
6. Gauvin D.V., Moore K.R., Youngblood B.D., Holloway F.A. The discriminative stimulus properties of legal, over-the-counter stimulants administered singly and in binary and ternary combinations. Psychopharmacology (Berlin). 110:1993;309-319.
7. Gurley B.J., Wang P., Gardner S.F. Ephedrine-type alkaloid content of nutritional supplements containing Ephedra sinica (Ma-huang) as determined by high performance liquid chromatography. J. Pharm. Sci. 87:1998;1547-1553.
8. Holloway F.A., Michaelis R.C., Huerta P.L. Caffeine-phenylethylamine combinations mimic the amphetamine discriminative cue. Life Sci. 36:1986;723-730.
9. Huang, K. C., ed. The pharmacology of Chinese herbs. Boca Raton, FL: CRC Press; 1993.
10. Huang J.-T., Ho B.T. Discriminative stimulus properties of d-amphetamine and related compounds in rats. Pharmacol. Biochem. Behav. 2:1974;669-673.
11. Mumford G.K., Holtzman S.G. Quantitative differences in the discriminative stimulus effects of low and high dose caffeine in the rat. J. Pharmacol. Exp. Ther. 258:1991;857-865.
12. Simpson, T. P.: Methcathinone: Chemistry and clandestine lab synthesis. Paper presented at the 1997 Annual Meeting of the Mid-Atlantic Association of Forensic Scientists, Roanoke, VA, May 1, 1997.
13. Wellman P.J., Miller D.K., Livermore C.L., Green T.A., McMahon L.R., Nation J.R. Effects of (-)ephedrine on locomotion, feeding, and nucleus accumbens dopamine in rats. Psychopharmacology (Berlin). 135:1998;133-140.
14. Young R., Glennon R.A. Discriminative stimulus properties of (-)ephedrine. Pharmacol. Biochem. Behav. 60:1998;771-775.
15. Young R., Gabryszuk M., Glennon R.A. -)Ephedrine and caffeine mutually potentiate one another's amphetamine-like stimulus effects. Pharmacol. Biochem. Behav. 61:1998;169-173.