Gallbladder carcinomas: An immunoprognostic evaluation of P53, Bcl-2, CEA and alpha-fetoprotein

Canadian Journal of Gastroenterology

Volumn 14, Issue 3, 2000, Pages 181-184

  Kanthan, R ^a   Radhi, J M ^a   Kanthan, S C ^a  

^a ROYAL UNIVERSITY HOSPITAL   (Canada)

Author keywords

Alpha fetoprotein; Bcl 2; Carcinoembryonic antigen; Gallbladder carcinoma; P53

Indexed keywords

ALPHA FETOPROTEIN; AVIDIN; BIOTIN; CARCINOEMBRYONIC ANTIGEN; PROTEIN BCL 2; PROTEIN P53;

ARTICLE; CANCER SURVIVAL; DISEASE COURSE; GALLBLADDER CARCINOMA; GENE EXPRESSION; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; METASTASIS; PRIORITY JOURNAL; PROGNOSIS; STATISTICAL ANALYSIS;

EID: 0034026086     PISSN: 08357900     EISSN: None     Source Type: Journal    
DOI: 10.1155/2000/865068     Document Type: Article

References (13)

1. Albores-Saavedra J, Alcantra-Vazquey A, Curz-Ortiz H, Herrera-Goepfert R. The precursor lesions of invasive gallbladder cancer: Hyperplasia, atypical hyperplasia and carcinoma in-situ. Cancer 1980;45:919-27.
2. Duarte I, Llonos O, Domke H, Hartz C, Valdivieso V. Metaplasia and precursor lesions of gallbladder carcinoma. Frequency, distribution and probability of detection in routine histologic samples. Cancer 1993;72:1878-84.
3. Watanabe M, Hori Y, Nojima T, et al. Alpha-fetoprotein-producing carcinoma of the gall bladder. Dig Dis Sci 1993,38:561-4.
4. Ng WK, Ng WF. Elevated serum alpha-fetoprotein in a patient with undifferentiated carcinoma of the gall bladder. J Clin Pathol 1995;48:1061-3.
5. Albores-Saavedra J, Nadji M, Morales AR, Henson DE. Carcinoembryonic antigen in normal, preneoplastic and neoplastic gallbladder epithelium. Cancer 1983;52:1069-72.
6. Roa I, Araya JC, Wistuba I, et al. [Immunohistochemical expression of the carcinoembryonic antigen in gallbladder cancer]. Rev Med Chil 1991;119:129-36.
7. Oshashi Y, Watanabe H, Ajioka Y, Hatakeyama K. P53 immunostaining distinguishes malignant from benign lesions of the gallbladder Pathol Int 1995;45:58-65.
8. Wee A, Teh M, Raju GC. Clinical importance of p53 protein in gallbladder carcinoma and its precursor lesions. J Clin Pathol 1994;47:453-6.
9. Teh M, Wee A, Raju GC. An immunohistochemical study of P53 protein in gallbladder and extrahepatic bile duct/ampullary carcinomas. Cancer 1994;74:1542-5.
10. Kamel D, Paakko P, Nuorva K, Vahakangas K, Soini Y. p53 and c-erb-B2 protein expression in adenocarcinomas and epithelial dysplasia of the gall bladder. J Pathol 1993;170:67-72.
11. Diamantis I, Karamitopoulou E, Perentes E, Zimmermann A. p53 protein immunoreactivity in extrahepatic bile duct and gallbladder cancer: correlation with tumor grade and survival. Hepatology 1995;22:774-9.
12. Fujit K, Yokozaki H, Yasui W, et al. High frequency of p53 gene mutation in adenocarcinomas of the gallbladder. Cancer Epidemiol Biomarkers Prev 1996;5:461-6
13. Itoi T, Watanabe H, Yoshida M, Ajioka Y, Nishikura K, Saito T. Correlation of p53 protein expression with gene mutation in gall bladder carcinomas. Pathol Int 1997;47:525-30.