Auditory-nerve-fiber responses to high-level clicks: Interference patterns indicate that excitation is due to the combination of multiple drives

Journal of the Acoustical Society of America

Volumn 107, Issue 5 I, 2000, Pages 2615-2630

  Lin, Tai ^a,b   Guinan Jr , John J ^a,b,c  

^a MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^b HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUDITORY STIMULATION; COCHLEA; COCHLEAR NERVE; EXCITATION; HAIR CELL; HISTOGRAM; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION;

ACOUSTIC STIMULATION; ANIMALS; CATS; COCHLEA; COCHLEAR NERVE; NERVE FIBERS;

EID: 0034026003     PISSN: 00014966     EISSN: None     Source Type: Journal    
DOI: 10.1121/1.428648     Document Type: Article

References (69)

1. Allen, J. B. (1983). "Magnitude and phase-frequency response to single tones in the auditory nerve," J. Acoust. Soc. Am. 73, 2071-2092.
2. Allen, J. B., and Neely, S. T. (1992). "Micromechanical models of the cochlea," Phys. Today July 40-47.
3. 1 potential," in Evoked Electrical Activity in the Auditory Nervous System, edited by R. F. Naunton and C. Fernández (Academic, New York), pp. 165-191.
4. Carney, L. H., McDuffy, M. J., and Shekhter, I. (1999). "Frequency glides in the impulse responses of auditory-nerve fibers," J. Acoust. Soc. Am. 105, 2384-2391.
5. Cheatham, M. A., and Dallos, P. (1989). "Two-tone suppression in inner hair cell responses," Hearing Res. 40, 187-196.
6. Cheatham, M. A., and Dallos, P. (1998). "The level dependence of response phase: Observations from cochlear hair cells," J. Acoust. Soc. Am. 104, 356-369.
7. Cody, A. R., and Mountain, D. C. (1989). "Low-frequency responses of inner hair cells: Evidence for a mechanical origin of peak splitting," Hearing Res. 41, 89-99.
8. Cooper, N. P. (1999). "Radial variation in the vibrations of the cochlear partition," in Recent Developments in Auditory Mechanics, edited by H. Wada and T. Takasaka (World Scientific, Singapore).
9. Cooper, N. P., and Rhode, W. S. (1995). "Nonlinear mechanics at the apex of the guinea-pig cochlea," Hearing Res. 82, 225-243.
10. Dallos, P. J., Popper, A. N., and Fay, R. R. (1996). The Cochlea (Springer-Verlag, New York).
11. Dallos, P., and Cheatham, M. A. (1989). "Nonlinearities in cochlear receptor potentials and their origins," J. Acoust. Soc. Am. 86, 1790-1798.
12. de Boer, E. (1993). "The sulcus connection. On a mode of participation of outer hair cells in cochlear mechanics," J. Acoust. Soc. Am. 93, 2845-2859.
13. de Boer, E., and Nuttall, A. L. (1997). "The mechanical waveform of the basilar membrane. I. Frequency modulations ("glides") in impulse responses and cross-correlation functions," J. Acoust. Soc. Am. 101, 3583-3592.
14. Freeman, D. M., and Weiss, T. F. (1990a). "Hydrodynamic forces on hair bundles at high frequencies," Hearing Res. 48, 31-36.
15. Freeman, D. M., and Weiss, T. F. (1990b). "Hydrodynamic analysis of a two-dimensional model for micromechanical resonance of free-standing hair bundles," Hearing Res. 48, 37-68.
16. Gifford, M. L., and Guinan, Jr., J. J. (1983). "Effects of crossed-olivocochlear-bundle stimulation on cat auditory nerve fiber responses to tones," J. Acoust. Soc. Am. 74, 115-123.
17. Goldstein, J. L. (1990). "Modeling rapid waveform compression on the basilar membrane as multiple-bandpass-nonlinearity filtering," Hearing Res. 49, 39-60.
18. Goldstein, J. L. (1991). "Modeling the nonlinear cochlear mechanical basis of psychophysical tuning," J. Acoust. Soc. Am. 90, 2267-2268.
19. Goldstein, J. L. (1995). "Relations among compression, suppression and combination tones in mechanical responses of the basilar membrane: Data and MBPNL model," Hearing Res. 89, 52-68.
20. Gray, P. R. (1967). "Conditional probability analyses of the spike activity of single neurons," Biophys. J. 7, 759-777.
21. Guinan, Jr., J. J. (1996). "The physiology of olivocochlear efferents," in The Cochlea, edited by P. J. Dallos, A. N. Popper, and R. R. Fay (Springer-Verlag, New York), pp. 435-502.
22. Guinan, Jr., J. J., and Gifford, M. L. (1988). "Effects of electrical stimulation of efferent olivocochlear neurons on cat auditory-nerve fibers. II. Spontaneous rate," Hearing Res. 33, 115-128.
23. Guinan, Jr., J. J., Guinan, S. S., and Norris, B. E. (1972). "Single auditory units in the superior olivary complex. I: Responses to sounds and classifications based on physiological properties," Int. J. Neurosci. 4, 101-120.
24. Gummer, A. W., Hemmert, W., and Zenner, H. P. (1996). "Resonant tectonal membrane motion in the inner ear: Its crucial role in frequency tuning," Proc. Natl. Acad. Sci. USA 93, 8727-8732.
25. Hubbard, A. E., Shatz, L., Yang, Z., and Mountain, D. C. (1999). "Multimode cochlear models," in Recent Developments in Auditory Mechanics, edited by H. Wada and T. Takasaka (World Scientific, Singapore).
26. Karavitaki, K. D., and Mountain, D. C. (1998). "Estimating electrically-evoked motion in the excised cochlea using video microscopy data," Assoc. Res. Otolaryngol. Abstr. 21, 180.
27. Kemp, D. T. (1978). "Stimulated acoustic emissions from within the human auditory system," J. Acoust. Soc. Am. 64, 1386-1391.
28. Khanna, S. M., and Hao, L. F. (1999). "Reticular lamina vibrations in the apical turn of a living guinea pig cochlea," Hearing Res. 132, 15-33.
29. Kiang, N. Y. S., Watanabe, T., Thomas, E. C., and Clark, L. F. (1965). Discharge Patterns of Single Fibers in the Cat's Auditory Nerve (MIT, Cambridge, MA).
30. Kiang, N. Y. S. (1984). "Peripheral neural processing of auditory information," in Handbook of Physiology. The Nervous System III (American Physiological Society, Bethesda, MD), pp. 639-674.
31. Kiang, N. Y. S. (1990). "Curious oddments of auditory-nerve studies," Hearing Res. 49, 1-16.
32. Kiang, N. Y. S., Baer, T., Marr, E. M., and Demont, D. (1969). "Discharge rates of single auditory nerve fibers as functions of tone level," J. Acoust. Soc. Am. 46, 106.
33. Kiang, N. Y. S., and Moxon, E. C. (1972). "Physiological considerations in artificial stimulation of the inner ear," Ann. Otol. Rhinol. Laryngol. 81, 714-731.
34. Liberman, M. C. (1978). "Auditory-nerve response from cats raised in a low-noise chamber," J. Acoust. Soc. Am. 63, 442-455.
35. Liberman, M. C. (1982). "Single-neuron labeling in the cat auditory nerve," Science 216, 1239-1241.
36. Liberman, M. C., and Kiang, N. Y. S. (1978). "Acoustic trauma in cats. Cochlear pathology and auditory-nerve activity," Acta Oto-Laryngol. Suppl. 358, 1-63.
37. Liberman, M. C., and Kiang, N. Y. S. (1984). "Single-neuron labeling and chronic cochlear pathology. IV. Stereocilia damage and alterations in rate-and phase-level functions," Hearing Res. 16, 75-90.
38. Lin, T., and Goldstein, J. L. (1995). "Quantifying 2-factor phase relations in non-linear responses from low characteristic-frequency auditory-nerve fibers," Hearing Res. 90, 126-138.
39. Møller, A. R., and Nilsson, H. G. (1979). "Inner ear impulse response and basilar membrane modeling," Acustica 41, 258-262.
40. Mountain, D. C. (1989). "Measurement of low-frequency receptor potentials in inner hair cells: A theoretical analysis," Hearing Res. 41, 101-106.
41. Mountain, D. C. (1998). "Modal analysis: A new paradigm for cochlear mechanics," Assoc. Res. Otolaryngol. Abstr. 21, 64.
42. Mountain, D. C., and Cody, A. R. (1999). "Multiple modes of inner hair cell stimulation," Hearing Res. 132, 1-14.
43. Nilsen, K. E., and Russell, I. J. (1999). "Timing of cochlear feedback: spatial and temporal representation of a tone across the basilar membrane," Nat. Neurosci. 2, 642-648.
44. Nuttall, A. L., Guo, M., and Ren, T. (1999). "The radial pattern of basilar membrane motion evoked by electric stimulation of the cochlea," Hearing Res. 131, 39-46.
45. Patuzzi, R., Johnstone, B. M., and Sellick, P. M. (1984). "The alteration of the vibration of the basilar membrane produced by loud sound," Hearing Res. 13, 99-100.
46. Pfeiffer, R. R., and Molnar, C. E. (1970). "Cochlear nerve fiber discharge patterns: Relationship to the cochlear microphonic," Science 167, 1614-1616.
47. Pfeiffer, R. R., and Kim, D. O. (1972). "Response patterns of single cochlear nerve fibers to click stimuli: Descriptions for cat," J. Acoust. Soc. Am. 52, 1669-1677.
48. Recio, A., Rich, N. C., Narayan, S. S., and Ruggero, M. A. (1998). "Basilar-membrane responses to clicks at the base of the chinchilla cochlea," J. Acoust. Soc. Am. 103, 1972-1989.
49. Richter, C. P., and Dallos, P. (1998). "Basilar membrane micro-mechanics measured in the gerbil inner ear," Assoc. Res. Otolaryngol. Abstr. 21, 181.
50. Ruggero. M. A., and Rich, N. C. (1983). "Chinchilla auditory-nerve responses to low-frequency tones," J. Acoust. Soc. Am. 73, 2096-2018.
51. Ruggero, M. A., Rich, N. C., and Recio, A. (1996a). "The effect of intense acoustic stimulation on basilar-membrane vibrations," Aud. Neurosci. 2, 329-345.
52. Ruggero, M. A., Rich, N. C., Shivapuja, B. G., and Temchin, A. N. (1996b). "Auditory-nerve responses to low-frequency tones: Intensity dependence," Aud. Neurosci. 2, 159-185.
53. Ruggero, M. A., Robles, L., and Rich, N. C. (1986). "Basilar membrane mechanics at the base of the chinchilla cochlea. II. Responses to low-frequency tones and relationship to microphonic and spike initiation in the VIII nerve," J. Acoust. Soc. Am. 80, 1375-1383.
54. Russell, I. J., and Sellick, P. M. (1983). "Low-frequency characteristics of intracellularly recorded receptor potentials in guinea-pig cochlear hair cells," J. Physiol. (London) 338, 179-206.
55. Ryugo, D. K. (1992). "The auditory nerve: Peripheral innervation, cell body morphology, and central projections," in The Mammalian Auditory Pathway: Neuroanatomy, edited by D. B. Webster, A. N. Popper, and R. R. Fay (Springer-Verlag, New York), Vol. 2, pp. 23-65.
56. Schoonhoven, R., Keijzer, J., Versnel, H., and Prijs, V. F. (1994). "A dual filter model describing single-fiber responses to clicks in the normal and noise-damaged cochlea," J. Acoust. Soc. Am. 95, 2104-2121.
57. Sellick, P. M., Patuzzi, R., and Johnstone, B. M. (1982). "Modulation of responses of spiral ganglion cells in guinea pig cochlea by low frequency sound," Hearing Res. 7, 199-221.
58. Sewell, W. F. (1984a). "Furosemide selectively reduces one component in rate-level functions from auditory-nerve fibers," Hearing Res. 15, 69-72.
59. Sewell, W. F. (1984b). "The effects of furosemide on the endocochlear potential and auditory-nerve fiber tuning curves in cats," Hearing Res. 14, 305-314.
60. Shera, C. A., and Guinan, Jr., J. J. (1999). "Frequency dependence of stimulus-frequency-emission phase: Implications for cochlear mechanics," in Recent Developments in Auditory Mechanics, edited by H. Wada and T. Takasaka (World Scientific, Singapore).
61. Sokolich, W. G., Hamernik, R. P., Zwislocki, J. J., and Schmiedt, R. A. (1976). "Inferred response polarities of cochlear hair cells," J. Acoust. Soc. Am. 59, 963-974.
62. Stankovic, K. M., and Guinan, Jr., J. J. (1999). "Medial efferent effects on auditory-nerve responses to tail-frequency tones I: Rate reduction," J. Acoust. Soc. Am. 106, 857-869.
63. Stankovic, K., M., and Guinan, J. J., Jr., "Medial efferent effects on auditory-nerve responses to tail-frequency tones II: Alteration of phase," J. Acoust. Soc. Am. (submitted).
64. Versnel, H., Schoonhoven, R., and Prijs, V. F. (1992). "Single-fibre and whole-nerve responses to clicks as a function of sound intensity in the guinea pig," Hearing Res. 59, 138-156.
65. Versnel, H., Prijs, V. F., and Schoonhoven, R. (1997). "Auditory-nerve fiber responses to clicks in guinea pigs with a damaged cochlea," J. Acoust. Soc. Am. 101, 993-1009.
66. Wong, J. C., Miller, R. L., Calhoun, B. M., Sachs, M. B., and Young, E. D. (1998). "Effects of high sound levels on responses to the vowel "eh" in cat auditory nerve," Hearing Res. 123, 61-77.
67. Xue, S., Mountain, D. C., and Hubbard, A. E. (1993). "Direct measurement of electrically-evoked basilar membrane motion," in Biophysics of Hair Cell Sensory Systems, edited by H. Duifhuis, J. W. Horst, P. van Dijk, and S. M. Netten (World Scientific, Singapore), pp. 361-368.
68. Zhang, L., Mountain, D. C., and Hubbard, A. E. (1997). "Shape and stiffness changes of the organ of Corti from base to apex cannot predict characteristic frequency changes: Are multiple modes the answer?," in Diversity in Auditory Mechanics, edited by E. R. Lewis, G. R. Long, R. F. Lyon, P. M. Narins, C. R. Steele, and E. Hecht-Poinar (World Scientific, Singapore), pp. 472-478.
69. Zwislocki, J. J. (1980). "Five decades of research on cochlear mechanics," J. Acoust. Soc. Am. 67, 1679-1685.