Effects of the phosphodiesterase III inhibitors olprinone, milrinone, and amrinone on hepatosplanchnic oxygen metabolism

Critical Care Medicine

Volumn 28, Issue 3, 2000, Pages 743-748

  Iribe, Gentaro ^a   Yamada, Haruhiko ^b   Matsunaga, Akira ^b   Yoshimura, Nozomu ^b  

^a KAGOSHIMA UNIVERSITY HOSPITAL   (Japan)

^b NONE

Author keywords

Amrinone; Cardiac surgery; Hepatic venous oxygen saturation; Milrinone; Olprinone; Phosphodiesterase III inhibitor; Splanchnic oxygen metabolism

Indexed keywords

AMRINONE; DOBUTAMINE; DOPAMINE; GLYCERYL TRINITRATE; LIDOCAINE; LOPRINONE; MILRINONE; PHOSPHODIESTERASE INHIBITOR;

ADULT; AGED; ARTERIAL GAS; ARTICLE; BLOOD GAS ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INFUSION; HEART INDEX; HEART SURGERY; HEMODYNAMICS; HEPATIC VEIN; HUMAN; OXYGEN CONSUMPTION; OXYGEN SATURATION; PRIORITY JOURNAL; SPLANCHNIC BLOOD FLOW;

EID: 0034024952     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200003000-00023     Document Type: Article

References (17)

1. 1. Edmunds LH Jr: Pulseless cardiopulmonary bypass. J Thorac Cardiovasc Surg 1982; 84: 800-804
2. 2. Leitman IM, Paull DE, Barie PS, et al: Intraabdominal complications of cardiopulmonary bypass operations. Surg Gynecol Obstet 1987; 165:251-254
3. 3. Heikkinen LO, Ala-Kulju KV: Abdominal complications following cardiopulmonary bypass in open-heart surgery. Scand J Thorac Cardiovasc Surg 1987; 21:1-7
4. 4. Collins JD, Bassendine MF, Ferner R, et al: Incidence and prognostic importance of jaundice after cardiopulmonary bypass surgery. Lancet 1983; i:1119-1123
5. 5. Takahashi T, Kunimoto F, Ichikawa H, et al: Gastric intramucosal pH and hepatic venous oximetry after cardiopulmonary bypass in valve replacement patients. Cardiovasc Surg 1996; 4:308-310
6. 6. Doglio GR, Pusajo JF, Egurrola MA, et al: Gastric mucosal pH as a prognostic index of mortality in critically ill patients. Crit Care Med 1991; 19:1037-1040
7. nd communication: Studies in dogs. Arzneimittelforschung 1989; 39:38-45
8. 8. Satoh H, Endoh M: Effects of a new cardiotonic agent 1,2-dihydro-6-methyl-2-oxo-5-[imidazo (1,2-a) pyridin-6-yl]-3-pyridine carbonitrile hydrochloride monohydrate (E-1020) on contractile force and cyclic AMP metabolism in canine ventricular muscle. Jpn J Pharmacol 1990; 52:215-224
9. 9. Takaoka H, Takeuchi M, Odake M, et al: Comparison of the effects on arterial-ventricular coupling between phosphodiesterase inhibitor and dobutamine in the diseases human heart. J Am Coll Cardiol 1993; 22:598-606
10. 10. Nagano K, Gelman S, Parks DA, et al: Hepatic oxygen supply-uptake relationship and metabolism during anesthesia in miniature pig. Anesthesiology 1990; 72:902-910
11. 11. Landow L, Phillips DA, Heard SO, et al: Gastric tonometry and venous oximetry in cardiac surgery patients. Crit Care Med 1991; 19:1226-1233
12. 12. Fiddian-Green RG, Baker S: Predictive value of the stomach wall pH for complications after cardiac operations: comparison with other monitoring. Crit Care Med 1987; 15: 153-156
13. 13. Fitzpatrick PG, Cinquegrani MP, Vakiener AR, et al: Hemodynamic and regional blood flow response to milrinone in patients with severe congestive heart failure: A dose-ranging study. Am Heart J 1987; 114:97-105
14. 14. Kizaki Z, Thurman RG: Stimulation of oxygen uptake by glucagon is oxygen dependent in perfused rat liver. Am J Physiol 1989; 256:G369-G376
15. 15. Heard SO, Helsmoortel CM, Kent JC, et al: Gastric tonometry in healthy volunteers: Effect of ranitidine on calculated intramural pH. Crit Care Med 1991; 19:271-274
16. 16. Kaisers U, Pappert D, Langrehr JM, et al: Dopamine, dopexamine and dobutamine in liver transplant recipients: A comparison of their effects on hemodynamics, oxygen transport and hepatic venous oxygen saturation. Transpl Int 1996; 9:214-220
17. 17. Kinoshita G, Washizu M, Murata N, et al: The effects of dopamine and dobutamine on liver oxygen supply-uptake relationship in the dog. J Vet Med Sci 1995; 57:287-291