Cellular immune response cytokine expression during the initial stage of bovine leukemia virus (BLV) infection determines the disease progression to persistent lymphocytosis

Comparative Immunology, Microbiology and Infectious Diseases

Volumn 23, Issue 3, 2000, Pages 197-208

  Yakobson, Bracha ^a   Brenner, J ^a   Ungar Waron, Hanna ^a   Trainin, Z ^a  

^a KIMRON VETERINARY INSTITUTE   (Israel)

Author keywords

Bovine leukemia virus; Cellular immunity; Cytokine Interferon gamma; Enzootic bovine leukosis; Lymphocytosis; persistent

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOVINE LEUKEMIA VIRUS; CATTLE DISEASE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE COURSE; GENE EXPRESSION; LYMPHOCYTE COUNT; LYMPHOCYTOSIS; MALE; MONONUCLEAR CELL; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CATTLE; CATTLE DISEASES; CHRONIC DISEASE; CYTOKINES; IMMUNITY, CELLULAR; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-2; LEUKEMIA VIRUS, BOVINE; LYMPHOCYTE ACTIVATION; LYMPHOCYTOSIS; MALE; RNA, MESSENGER;

ANIMALIA; BOS TAURUS; BOVINAE; BOVINE LEUKEMIA VIRUS; RNA VIRUSES;

EID: 0034024267     PISSN: 01479571     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0147-9571(99)00074-0     Document Type: Article

References (20)

1. Francki R.I.B., Fauquet C.M., Knudson D.L., Brown F. Classification and Nomenclature of viruses. Fifth report of the International Committee on Taxonomy of viruses. Arch. Virol. (Suppl.). 2:1991;297.
2. Kenyon S.J., Piper C.E. Cellular basis of persistent lymphocytosis in cattle infected with bovine leukemia virus. Infect. Immun. 16:1977;891-897.
3. Kono Y., Arai K., Sentsui H., Matsukawa S., Itohara S. Protection against bovine leukemia virus infection in sheep by active and passive immunization. Jpn. J. Vet. Sci. 48:1986;117-125.
4. Wang J., Boyer D., Ugen K., Srikantan V., Ayyavoo V., Agadjanyan M., Williams W., Newman M., Coney L., Carrano R., Weiner D.B. Nucleic-acid based immunization against HIV-1: induction of protective in vivo immune responses. AIDS. 9:1995;. (Suppl. AI 5159).
5. Ploegh H.L. Viral strategies of immune invasion. Science. 280:1998;248-253.
6. Taniguchi T., Minami Y. The IL-2/IL-2 receptor system: a current overview. Cell. 73:1993;5-8.
7. Fiorentino D.F., Bond M.W., Mosmann T.R. Two types of mouse helper T-cells. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 170:1989;2081-2095.
8. Pyeon D., O'Reilly K.L., Splitter G.A. Increased interleukin-10 mRNA expression in tumor bearing or persistently lymphocytotic animals infected with bovine leukemia virus. J. Virol. 70:1996;5706-5710.
9. Clerici M., Shearer G.M. A Th1-Th2 switch is a critical step in the ethiology of HIV infection. Immunol. Today. 14:1993;107-111.
10. Benveniste O., Vaslin B., Le Grand R., Fouchet P., Omessa V., Theodore F., Fretier P., Clayette P., Boussin F., Dormont D. Interleukin 1β, interleukin 6, tumor necrosis factor α and interleukin 10 responses in peripheral blood mononuclear cells of cynomolgus macaques during acute infection with SIV mac 251. AIDS. Res. Hum. Retroviruses. 12:1996;241-250.
11. Benveniste O., Vaslin B., Le Grand R., Cheret A., Matheux F., Theodore F., Cranage M.P., Dormont D. Comparative (IL)-2/interferon (IFN-)-γ and IL-4/IL-10 responses during acute infection of macaques inoculated with attenuated net-transacted or pathogenic SIV mac 251 virus. Proc. Natl. Acad. Sci. USA. 93:1996;3658-3663.
12. Keefe R.G., Ferrick D.A., Stott J.L. Cytokine transcription in lymph nodes of cattle in different stages of bovine leukemia virus infection. Vet. Immunol. Immunopathol. 59:1997;271-283.
13. Yakobson B., Brenner J., Ungar-Waron H., Trainin Z. Short-termed expression of interleukin-12 during experimental BLV infection may direct disease progression to persistent lymphocytosis. Vet. Immunol. Immunopathol. 64:1998;207-218.
14. + lymphocytes by reverse transcriptase polymerase chain reaction. Vet. Immunol. Immunopathol. 49:1995;39-50.
15. Ungar-Waron H., Paz R., Brenner J., Yakobson B., Partosh N., Trainin Z. Experimental infection of calves with bovine leukemia virus (BLV): an applicable model of a retroviral infection. Vet. Immunol. Immunopathol. 67:1999;195-201.
16. Dittmer U., Hunsman G. Long-term non-progressive human immunodeficiency virus infection: new insights from the simian immunodeficiency virus model. J. Gen. Virol. 78:1997;979-984.
17. Heeney J.L. AIDS: a disease of impaired Th-cell renewal? Immunology Today. 16:1995;515-519.
18. + T-cells in response to gag and env-encoded BLV proteins. J. Virol. 70:1996;7584-7593.
19. Burdin N., Kooten C.V., Galibert J., Abrams S., Wijdenes Y., Banchereau Y., Roussett F. Endogenous IL-6 and IL-10 contribute to the differentiation of CD40 activated human B lymphocytes. J. Immunol. 154:1995;2533-2544.
20. Depelchin A., Lettesson J.J., Lostrie Trussart N., Mammerickx M., Portetelle D., Burny A. Bovine leukemia virus (BLV)-infected B-cells express a marker similar to the CD5 T cell marker. Immunol. Lett. 20:1989;69-76.