'New variant' Creutzfeldt-Jakob disease and bovine spongiform encephalopathy

Nature Medicine

Volumn 6, Issue 3, 2000, Pages 258-259

  Bruce, Moira E ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PRION PROTEIN;

AMINO ACID SEQUENCE; BOVINE SPONGIFORM ENCEPHALOPATHY; CREUTZFELDT JAKOB DISEASE; DISEASE TRANSMISSION; GENE; HUMAN; IMMUNOBLOTTING; INCUBATION TIME; NONHUMAN; PRION; PRIORITY JOURNAL; SHORT SURVEY; TRANSGENIC MOUSE;

ADULT; AGED; ANIMALS; CATTLE; CREUTZFELDT-JAKOB SYNDROME; ENCEPHALOPATHY, BOVINE SPONGIFORM; FRANCE; GREAT BRITAIN; HUMANS; MICE; MICE, TRANSGENIC; MIDDLE AGED;

BOVINAE; MUS MUSCULUS;

EID: 0034023961     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/73098     Document Type: Short Survey

References (10)

1. Will, R.G. et al. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347, 921-925 (1996).
2. Will, R.C., Alpers, M.P., Dormont, D., Schonberger, L.B. & Tateishi, J. in Prion Biology and Diseases (ed. Prusiner, S.B.) 465-507 (Cold Spring Harbor, New York, 1999).
3. Bruce, M.E. Scrapie strain variation and mutation. Br. Med. Bull. 49, 822-838 (1993).
4. Collinge, J., Sidle, K.C.L., Meads, J., Ironside, J. & Hill, A.F. Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. Nature 383, 685-690 (1996).
5. Bruce, M. et al. Transmission of bovine spongiform encephalopathy and scrapie to mice-strain variation and the species barrier. Phil. Trans. R. Soc. Lond. B 343, 405-411 (1994).
6. Fraser, H. et al. Transmission of feline spongiform encephalopathy to mice. Vet. Rec 134, 449 (1994).
7. Bruce, M.E. et al. Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 389, 498-501 (1997).
8. Scott, M.R. et al. Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans. Proc. Natl. Acad. Sci, USA 96, 15137-15142 (1999).
9. Hill, A.F. et al. The same prion strain causes vCJD and BSE. Nature 389, 448-450 (1997).
10. Hill, A.F. et al. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 353, 183-189 (1999).