Genetic inheritance of body mass index in African-American and African families

Genetic Epidemiology

Volumn 18, Issue 4, 2000, Pages 360-376

  Colilla, Susan ^a,c   Rotimi, Charles ^b   Cooper, Richard ^b   Goldberg, Jack ^c   Cox, Nancy ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Blacks; Obesity; Segregation analysis

Indexed keywords

ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; FAMILY; FEMALE; GENE FREQUENCY; GENETIC VARIABILITY; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; MALE; NEGRO; OBESITY;

AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; BODY MASS INDEX; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LIKELIHOOD FUNCTIONS; MALE; MODELS, GENETIC; MODELS, STATISTICAL; NIGERIA; NUCLEAR FAMILY; OBESITY; RISK FACTORS; UNITED STATES;

EID: 0034023640     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(200004)18:4<360::AID-GEPI8>3.0.CO;2-H     Document Type: Article

References (48)

1. Aikake H. 1974. A new look at the statistical model identification. IEEE Trans Autom Control 19:716-723.
2. Bonney GE. 1984. On the statistical determination of major gene mechanisms in continuous human traits: Regressive models. Am J Med Genet 18:731-49.
3. Bonney GE. 1986. A note on the basis of regressive models for genetic analysis. Genet Epidemiol Suppl 1:37-42.
4. Borecki IB, Bonney GE, Rice T, Bouchard C, and Rao DC. 1993. Influence of genotype-dependent effects of covariates on the outcome of segregation analysis of the body mass index. Am J Hum Genet 53:676-87.
5. Borecki IB, Higgins M, Schreiner PJ, Arnett DK, Mayer-Davis E, Hunt SC, and Province MA. 1998. Evidence of multiple determinants of the body mass index: The National Heart, Lung, and Blood Institute Family Heart Study. Obes Res 6:107-14.
6. Bouchard C, Perusse L. 1988. Heredity and body fat. Ann Rev Nutr 8:259-77.
7. Bray GA. 1985. Complications of obesity. Ann Intern Med 103:1052-62.
8. Burke GL, Jacobs DR, Sprafka JM, Savage PJ, Sidney S, Wagenknecht LE. 1990. Obesity and overweight in young adults: The CARDIA study. Prev Med 19:476-88.
9. Cooper R, Rotimi C, Kaufman J, and Luke A. 1996. Nutritional status in rural Nigerians. Lancet 347:331.
10. Cooper R, Rotimi C, Ataman S, McGee D, Osotimehin B, Kadiri S, Muna W, Kingue S, Fraser H, Forrester T, Bennett F, Wilks R. 1997. The prevalence of hypertension in seven populations of West African origin. Am J Public Health 87:160-8.
11. Demenais F, Martinez M, Andrieu N. 1993. The transmission probability model is useful to prevent false inference. Am J Hum Genet 52:441-2.
12. Dorn JM, Schisterman EF, Winkelstein W, Trevisan M. 1997. Body mass index and mortality in a general population sample of men and women. Am J Epidemiol 146:919-31.
13. Dyer AR, Elliott P. 1989. The INTERSALT study: relations of body mass index to blood pressure. J Hum Hypertens 3:299-308.
14. Ebomoyi EW, Wickremasinghe AR, Cherry FF. 1991. Anthropometric indicators of children's nutrition in two Nigerian communities. J Biosoc Sci 23:33-8.
15. Fabsitz RR, Carmelli D, Hewitt JK. 1992. Evidence for independent genetic influences on obesity in middle age. Int J Obesity 16:657-66.
16. Folsom AR, Burke GL, Byers CL, Hutchinson RG, Heiss G, Flack JM, Jacobs DR Jr, Caan B. 1991. Implications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies. Am J Clin Nutr 53:1604S-1611S.
17. Gillum RF. 1987. Overweight and obesity in black women: A review of published data from the National Center for Health Statistics. J Natl Med Assoc 79:865-71.
18. Harlan WR. 1988. Secular trends in body mass in the United States, 1960-1980. Am J Epidemiol 128: 1065-74.
19. Hasstedt SJ, Hoffman M, Leppert MF, Elbein SC. 1997. Recessive inheritance of obesity in familial non-insulin-dependent diabetes mellitus, and lack of linkage to nine candidate genes. Am J Hum Genet 61:668-77.
20. Heiba IM, Elston RC, Klein BE. 1994. Sibling correlations and segregation analysis of age-related maculopathy: The Beaver Dam Eye Study. Genet Epidemiol 11:51-67.
21. Hubert HB, Feinlaub M, McNamara PM, Castelli WP. 1983. Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 67:968-77.
22. Johnson JL, Heineman EF, Heiss G, Hames CG, Tyroler HA. 1986. Cardiovascular disease risk factors and mortality among black women and white women aged 40-64 years in Evans County, Georgia. Am J Epidemiol 123:209-20.
23. Korkeila M, Kaprio J, Rissanen A., Koskenvuo M. 1991. Effects of gender and age on the heritability of body mass index. Int J Obesity 15:647-54.
24. Kumanyika S. 1987. Obesity in black women. Epidemiol Rev 9:31-50.
25. Lewis CE, Smith DE, Wallace DD, Williams OD, Bild DE, Jacobs DR Jr. 1997. Seven-year trends in body weight and associations with lifestyle and behavioral characteristics in black and white young adults: The CARDIA Study. Am J Pub Health 87:635-42.
26. Manson JE, Colditz GA, Stampfer MJ, Willet WC, Rosner B, Monson RR, Speizer FE, Hennekens CH. 1990. A prospective study of obesity and risk of coronary heart disease in women. N Engl J Med 322:882-9.
27. Manson JE, Willet WC, Stampfer MJ, Colditz GA, Hunter DJ, Hankinson SE, Hennekens CH, Speizer FE. 1995. Body weight and mortality among women. N Engl J Med 333:677-85.
28. Mayer J. 1965. Genetic factors in human obesity. Ann NY Acad Sci 131:412-21.
29. Meyer JM, Stunkard AJ. 1994. Twin studies of human obesity. In: Bouchard C, editor. The genetics of obesity. Ann Arbor: CRC Press. p 63-78.
30. Moll PP, Burn TL, Lauer RM. 1991. The genetic and environmental sources of body mass index variability: The Muscatine Ponderosity Family Study. Am J Hum Genet 49:1243-55.
31. Ness R, Laskarzewski P, Price RA. 1991. Inheritance of extreme overweight in black families. Hum Biol 63:39-52.
32. Parra EJ, Marcini A, Akey J, Martinson J, Batzer MA, Cooper R, Forrester T, Allison DB, Deka R, Ferrell RE, Shriver MD. 1998. Estimating African American admixture proportions by use of population-specific alleles. Am J Hum Genet 63:1839-51.
33. Perusse L, Tremblay A, LeBlanc C, Cloninger CR, Reich T, Rice J, Bouchard C. 1988. Familial resemblance in energy intake: contribution of genetic and environmental factors. Am J Clin Nutr 47:629-35.
34. Perusse L, Tremblay A, LeBlanc C, Bouchard C. 1989. Genetic and environmental influences on level of habitual physical activity and exercise participation. Am J Epidemiol 1012-22.
35. Price RA. 1996. Within birth cohort segregation analyses support recessive inheritance of body mass index in white and African-American families. Int J Obesity 20:1044-7.
36. Price RA, Ness R, Laskarzewski P. 1990. Common major gene inheritance of extreme overweight Hum Biol 62:747-65.
37. Price RA, Charles MA, Pettitt DJ, Knowler WC. 1994. Obesity in Pima Indians: genetic segregation analyses of body mass index complicated by temporal increases in obesity. Hum Biol 66:251-74.
38. Province MA, Arnqvist P, Keller J, Higgins M, Rao DC. 1990. Strong evidence for a major gene for obesity in the large, unselected total Community Health Study of Tecumseh. Am J Hum Genet 47S:A143.
39. Rice T, Borecki IB, Bouchard C, Rao DC. 1993. Segregation analysis of body mass index in an unselected French-Canadian sample: the Quebec Family Study. Obes Res 1:288-94.
40. Rice T, Province M, Perusse L, Bouchard C. Rao DC. 1994. Cross-trait resemblance for body fat and blood pressure: Familial correlations in the Quebec Family Study. Am J Hum Genet 55:1019-29.
41. Rotimi CN, Cooper RS, Ataman SL, Osotimehin B, Kadiri S, Muna W, Kingue S, Fraser H, McGee D. 1995. Distribution of anthropometric variables and the prevalence of obesity in populations of West African origin: The International Collaborative Study on Hypertension in Blacks (ICSHIB). Obes Res 3(Suppl 2):95s-105s.
42. S.A.G.E. Statistical Analysis for Genetic Epidemiology, Release 2.2. 1995. Computer program package available from Department of Epidemiology and Biostatistics, Rammelkamp Center for Education and Research, Metro Health Campus, Case Western Reserve University, Cleveland, OH.
43. SAS Institute. 1997. SAS release 6.12. Cary, NC: SAS Institute.
44. Schork NJ, Weder AB, Trevisan M, Laurenzi M. 1994. The contribution of pleiotropy to blood pressure and body-mass index variation: The Gubbio Study. Am J Hum Genet 54:361-73.
45. Sorensen TI, Stunkard AJ. 1994. Overview of adoption studies In: Bouchard, C, editor. The Genetics of Obesity. Ann Arbor: CRC Press. p 49-62.
46. Taubes G. 1998. As obesity rates rise, experts struggle to explain why. Science 280:1367-8.
47. Tiret L, Abel L, Rakotovao R. 1993. Effect of ignoring genotype-environment interaction on segregation analysis of quantitative traits. Genet Epidemiol 10:581-6.
48. U.S. Census Bureau. 1990. http://www.census.gov