Generalized nonlinear models for pharmacokinetic data

Biometrics

Volumn 56, Issue 1, 2000, Pages 81-88

  Lindsey, J K ^a   Byrom, W D ^b   Wang, J ^a   Jarvis, P ^a   Jones, B ^a  

^a DE MONTFORT UNIVERSITY   (United Kingdom)

^b ABBOTT LABORATORIES   (United States)

Author keywords

Fixed effects; Gamma distribution; Kernel density estimation; Left censoring; Log Cauchy distribution; Log Laplace distribution; Log normal distribution; One compartment model; Random effects; Response surface; Weibull distribution

Indexed keywords

BIOMOLECULES; NONLINEAR SYSTEMS; NORMAL DISTRIBUTION; PHARMACOKINETICS; RANDOM PROCESSES; WEIBULL DISTRIBUTION;

CAUCHY DISTRIBUTION; FIXED EFFECTS; GAMMA DISTRIBUTION; KERNEL DENSITY ESTIMATION; LAPLACE DISTRIBUTIONS; LEAVE CENSORING; LOG CAUCHY DISTRIBUTION; LOG LAPLACE DISTRIBUTION; LOG-NORMAL DISTRIBUTION; ONE COMPARTMENT MODELS; RANDOM EFFECTS; RESPONSE SURFACE;

METABOLITES;

FLOSEQUINAN;

ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; COMPUTER PROGRAM; HEART FAILURE; HUMAN; NONLINEAR SYSTEM; NORMAL HUMAN; PHARMACOKINETICS; PHASE 1 CLINICAL TRIAL; STATISTICAL MODEL;

EID: 0034020940     PISSN: 0006341X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0006-341X.2000.00081.x     Document Type: Article

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