Studies on the effects of gentamicin on rat metanephric development in vitro

Nephrology

Volumn 5, Issue 1-2, 2000, Pages 115-123

  Cullen, Luise A ^a   Young, Richard J ^a   Bertram, John F ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Development; Gentamicin; Kidney; Metanephros; Stereology

Indexed keywords

GENTAMICIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; DRUG EFFECT; EMBRYO; ESSENTIAL HYPERTENSION; KIDNEY EPITHELIUM; NEPHRON; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; RAT; STEREOLOGY;

EID: 0034019590     PISSN: 13205358     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1797.2000.00512.x     Document Type: Article

References (22)

1. 1. Brenner BM, Garcia DL, Anderson S. Glomeruli and blood pressure. Less of one more the other? Am. J. Hypetens. 1988; 1: 355-47.
2. 2. Brenner BM, Milford EL. Nephron underdosing: A programmed cause of chronic renal allograft failure. Am. J. Kidney Dis. 1993; 21: 66-72.
3. 3. Brenner BM, Chertow GM. Congenital oligonephropathy and the etiology of adult hypertension and progressive renal injury. Am. J. Kidney Dis. 1994; 23: 171-5.
4. 4. Clark AT, Bertram JF. Molecular regulation of nephron endowment. Am. J. Physiol. Renal Physiol. 1999; 276: F485-F497.
5. 5. Lucus S, Silva V, Miraglia S, Gil F. Functional and morphometric evaluation of offspring kidney after intrauterine undernutrition. Pediatr. Nephrol. 1997; 11: 719-23.
6. 6. Hinchliffe S, Lynch M, Sargent P, Howard C, Van Velzen D. The effect of intrauterine growth retardation on the development of renal nephrons. Br. J. Obst. Gyn. 1992; 99: 296-301.
7. 7. Mertlet-Benichou C, Gilbert T, Muffat-Joly M, Lelievre-Pegorier M, Leroy B. Intrauterine growth retardation leads to a permanent nephron deficit in the rat. Pediatr. Nephrol. 1994; 8: 175-80.
8. 8. Gilbert T, Lelievre-Pegorier M, Malienou R, Meulemans A, Merlet-Benichou C. Effects of prenatal and postnatal exposure to gentamicin on renal differentiation in the rat. Toxicology 1987; 43: 301-13.
9. 9. Gilbert T, Nabarra B, Merlet-Benichou C. Light-and electron-microscopic analysis of the kidney in newborn rats exposed to gentamicin in utero. Am. J. Pathol. 1988; 130: 33-43.
10. 10. Gilbert T, Gaonach S, Moreau E, Merlet-Benichou C. Defect of nephrogenesis induced by gentamicin in rat metanephric organ culture. Lab. Invest. 1994; 70: 656-66.
11. 11. Gilbert T, Cibert C, Moreau E, Geraud G, Merlet-Benichou C. Early detect in branching morphogenesis of the ureteric bud in induced nephron deficit. Kidney Int. 1996; 50: 783-95.
12. 12. Gundersen HJ, Bendtsen TF, Korbo L et al. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1988; 96: 379-94.
13. 13. Gilbert T, Lelievre-Pegorier M, Merlet-Benichou C. Immediate and long term renal effects of foetal exposure to gentamicin. Pediatr. Nephrol. 1990; 4: 445-50.
14. 14. Gilbert T, Lelievre-Pegorier M, Merlet-Benichou C. Long-term effects of mild oligonephronia induced in utero by gentamicin in the rat. Pediatr. Res. 1991; 10: 450-6.
15. 15. Pepicelli, CV, Kispert A, Rowitch DH, McMahon AP. GDNF induces branching, increased cell proliferation in the ureteric duct of the mouse. Dev. Biol. 1997, 192: 193-8.
16. 16. Sainio K, Suvanto P, Davies JA et al. Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development 1997; 124: 4077-87.
17. 17. Vega QC, Worby CA, Lechner MS et al. Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. Proc. Natl Acad. Sci. USA 1996; 10657-10661.
18. 18. Bennett WM, Mela-Riker LM, Houghton DC, Gilbert DN, Buss WC. Microsomal protein synthesis inhibition: An early manifestation of gentamicin nephrotoxicity. Am. J. Physiol. 1988; 255: F265-F269.
19. 19. Buss WC, Piatt MK, Kauten R. Inhibition of mammalian microsomal protein synthesis by aminoglycoside antibiotics. J. Antimicrob. Chemother. 1984; 14: 231-41.
20. 20. Buss WC, Piatt MK. Gentamicin administered in vivo reduces protein synthesis in microsomes subsequently isolated from the rat kidneys but not from rat brains. J. Antimicrob. Chemother. 1985; 15: 715-21.
21. 21. Van Bambeke F, Mingeot-Leclercq MP, Schanck A, Brasseur R, Tulkens PM. Alterations in membrane permeability induced by aminoglycoside antibiotics: Studies on liposomes and cultured cells. Eur. J. Pharmacol. 1993; 247: 155-68.
22. 22. Simmons CF, Bogusky RT, Humes HD. Inhibitory effects of gentamicin on renal mitochondrial oxidative phosphorylation. J. Pharmacol. Exp. Ther. 1980; 214: 709-15.