Cure of Helicobacter pylori infection does not improve symptoms in non-ulcer dyspepsia patients - A double-blind placebo-controlled study

Alimentary Pharmacology and Therapeutics

Volumn 14, Issue 3, 2000, Pages 317-324

  Miwa, H ^a   Hirai, S ^a   Nagahara, A ^a   Murai, T ^a   Nishiraa, T ^a   Kikuchi, S ^a   Takei, Y ^a   Watanabe, S ^a   Sato, N ^a  

^a JUNTENDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; CLARITHROMYCIN; OMEPRAZOLE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DYSPEPSIA; ENTERITIS; FEMALE; GASTRITIS; GLOSSITIS; HEADACHE; HELICOBACTER PYLORI; HISTOLOGY; HUMAN; INTESTINE INFECTION; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MALE; PATIENT COMPLIANCE; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SYMPTOM; TASTE DISORDER;

ADULT; AGED; AMOXICILLIN; ANTI-BACTERIAL AGENTS; ANTI-ULCER AGENTS; CLARITHROMYCIN; DOUBLE-BLIND METHOD; DYSPEPSIA; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; OMEPRAZOLE; PATIENT COMPLIANCE; PENICILLINS; TIME FACTORS; TREATMENT OUTCOME;

EID: 0034018720     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.2000.00706.x     Document Type: Article

References (37)

1. 1 Sung JJS. Chung S, Ling TKW, et al. Antibacterial treatment of gastric ulcers associated with Helicobacter pylori. N Eng J Med 1995; 332: 139-42.
2. 2 Hentschel E, Brandstätter G, Dragosics B, et al. Effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. N Eng J Med 1993; 328: 308-12.
3. 3 NIH consensus development panel on Helicobacter pylori in peptic ulcer disease. Helicobacter pylori in peptic ulcer disease. J Am Med Assoc 1994; 272: 65-9.
4. 4 The European Helicobacter pylori study group. Current European concepts in the management of Helicobacter pylori infection. The Maastricht consensus report. Gut 1997; 41: 8-13.
5. 5 Colin-Jones DG, Bloom B, Bodemar G, et al. Management of dyspepsia; report of a working party. Lancet 1988; 1: 576-9.
6. 6 Fisher RS, Parkman HP. Management of nonulcer dyspepsia. N Eng J Med 1998; 339: 1376-81.
7. 7 Rokkas T, Pursey C, Uzoechina E, et al. Campylobacter pylori and non-ulcer dyspepsia. Am J Gastroenterol 1987; 82: 1149-87.
8. 8 Rauws EA, Langenberg W, Houthoff H, Zanen HC, Tytgat NJ. Campylobacter pyloridis-associated chronic active antral gastritis. Gastroenterology 1988; 94: 33-40.
9. 9 Hunt RH. Hp and pH - The relevance of gastric acid to the treatment of Helicobacter pylori infection. J Gastroenterol 1994; 29 (Suppl. V:II): 128-33.
10. 10 Testoni PA, Bagnolo F, Colombo E, Bonassi U, Tosi T. The correlation in dyspeptic patients of Helicobacter pylori infection with changes in interdigestive gastroduodenal motility patterns but not in gastric emptying. Helicobacter 1996; 1: 229-37.
11. 11 Laheij R, Jansen J, Van de Lisdonk E, Severens J, Verbeek A. Review article: symptom improvement through eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. Aliment Pharmacol Ther 1996; 10: 843-50.
12. 12 Talley N. A critique of therapeutic trials in Helicobacter pylori-positive functional dyspepsia. Gastroenterology 1994; 106: 1174-83.
13. 13 Miwa H, Nagahara A, Sato K, et al. Efficacy of 1-week PPI/AC therapy for H. pylori infection in the Japanese population. J Gastroenterol Hepatol 1999; 14: 317-21.
14. 13C urea breath test for detection of Helicobacter pylori infection with fasting subjects. Helicobacter 1997; 2: 82-5.
15. 13C urea breath test for detection of H. pylori infection in fasting patients. J Gastroenterol Hepatol 1998; 13: 1039-43.
16. 16 Sipponen P, Kekki M, Siurala M. The Sydney system: epidemiology and natural history of chronic gastritis. J Gastroenterol Hepatol 1991; 6: 244-51.
17. 17 Svedlund J. Sjödin I, Dotevall G. GSRS - a clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig Dis Sci 1988; 33: 129-34.
18. 18 O'Morain C, Gilvarry J. Eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. Scand J Gastroenterol 1993; 28 (Suppl. 196): 30-3.
19. 19 McCarthy C, Patchett S, Collins R, Beattie S, Keane C, O'Morain C. Long-term prospective study of Helicobacter pylori in nonulcer dyspepsia. Dig Dis Sci 1995; 40: 114-9.
20. 20 Elta G, Scheiman J, Barnett J, et al. Long-term follow up of Helicobacter pylori treatment in non-ulcer dyspepsia patients. Am J Gastroenterol 1995; 90: 1089-93.
21. 21 Gilvarry J, Buckley MJ, Beattie S, Hamilton H, O'morain CA. Eradication of Helicobacter pylori affects symptoms in nonulcer dyspepsia. Scand J Gastroenterol 1997; 32: 535-40.
22. 22 McColl K, Murray L, El-Omar E, et al. Symptomatic benefit from eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia. N Engl J Med 1998; 339: 1869-974.
23. 23 Blum AL, Talley NJ, van O'Morain C, et al. Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. N Engl J Med 1998; 339: 1875-81.
24. 24 Talley NJ, Janssens J, Lauritsen K, Raćz István BollingSternevald E. Eradication of Helicobacter pylori in functional dyspepsia: randomized double blind placebo controlled trial with 12 months' follow up. Br Med J 1999; 318: 833-7.
25. 25 Miwa H, Ohkura R, Murai T, et al. Effectiveness of OAC therapy for H. pylori infection in Japanese population. Helicobacter 1998; 3: 132-8.
26. 26 Miwa H, Nagahara A, Sato K, et al. Efficacy of 1 week PPI/AC therapy for H. pylori infection in the Japanese population. J Gastroenterol Hepatol 1999; 14: 317-21.
27. 27 Miwa H, Ohkura R, Murai T, et al. Impact of rabeprazole, a new proton pump inhibitor, in PPI/AC therapy for Helicobacter pylori infection - comparison with omeprazole and lansoprazole. Aliment Pharmacol Ther 1999; 13: 741-6.
28. 28 Wittman EM, Mravunac M, Becx MJ, et al. Improvement of gastric inflammation and resolution of epithelial damage one year after eradication of Helicobacter pylori. J Clin Pathol 1995; 48: 250-6.
29. 29 McNulty CA, Gearty JC, Crump B, et al. Campylobacter pyloridis and associated gastritis: investigator blind, placebo controlled trial of bismuth salicylate and erythromycin ethylsuccinate. Br Med J 1986; 293: 645-9.
30. 30 Talley NJ, Weaver AL, Tesmer DL, Zinsmeister AR. Lack of discriminant value of dyspepsia subgroups in patients referred for upper endoscopy. Gastroenterology 1993; 105: 1378-86.
31. 31 Talley NJ. The role of Helicobacter pylori in non-ulcer dyspepsia: a debate-against. Gastroenterol Clin North Am 1993; 22: 153-67.
32. 32 Sobala GM, Dixon MF, Axon ATR. Symptomatology of Helicobacter pylori associated dyspepsia. Eur J Gastroenterol Hepatol 1990; 2: 445-9.
33. 33 Go KL, Parasakthi SC, Wong NW, Lo YL, Puthucheary SD. Helicobacter pylori infection and non-ulcer dyspepsia: The effect of treatment with colloidal bismuth subcitrate. Scand J Gastroenterol 1991; 26: 1123-31.
34. 34 Kang JY, Tay HH, Wee A, Guan R, Math MV, Yap I. Effect of colloidal bismuth subcitrate on symptoms and gastric histology in non-ulcer dyspepsia. A double blind placebo controlled study. Gut 1990; 31: 476-80.
35. 35 Vaira D, Holton J, Ainley C, et al. Double blind trial of colloidal bismuth subcitrate versus placebo in Helicobacter pylori positive patients with non-ulcer dyspepsia. Ital J Gastroenterol 1992; 24: 400-4.
36. 36 Morgan D, Kraft W, Bender M, Peason A. Nitrofurans in the treatment of gastritis associated with campylobacter pylori. Gastroenterology 1988; 95: 1178-84.
37. 37 Glupczynski Y, Burette A, Labbe M, Deprez C, De reuck M, Deltenre M. Campylobacter pylori-associated gastritis: a double-blind placebo-controlled trial with amoxycillin. Am J Gastroenterol 1988; 83: 365-72.