Crystal structures of 3-isopropylmalate dehydrogenases with mutations at the C-terminus: Crystallographic analyses of structure-stability relationships

Protein Engineering

Volumn 13, Issue 4, 2000, Pages 253-258

  Nurachman, Zeily ^a   Akanuma, Satoshi ^b   Sato, Takao ^a   Oshima, Tairo ^c   Tanaka, Nobuo ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

3 Isopropylmalate dehydrogenase; Closed conformation; Minor groove; Modified C terminus; Paperclip motion

Indexed keywords

3 ISOPROPYLMALATE DEHYDROGENASE; AMINO ACID;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMOSTABILITY; THERMUS THERMOPHILUS; X RAY DIFFRACTION;

BACTERIA (MICROORGANISMS); THERMUS THERMOPHILUS;

EID: 0034018098     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/13.4.253     Document Type: Article

References (20)

1. Akanuma, S., Yamagishi, A., Tanaka, N. and Oshima, T. (1996) J. Bacteriol., 178, 6300-6304.
2. Akanuma, S., Qu, C., Yamagishi, A., Tanaka, N. and Oshima, T. (1997) FEBS Lett., 410, 141-144.
3. Brünger A.T. (1992) A System for X-ray Crystallography and NMR, X-PLOR, Version 3.1. Yale University Press, New Haven, CT.
4. Fersht, A.R. and Serrano, L. (1993) Curr. Opin. Struct. Biol., 3, 75-83.
5. Imada, K., Sato, M., Tanaka, N., Katsube, K., Matsuura, Y. and Oshima, T. (1991) J. Mol. Biol., 222, 735-738.
6. Jones, T.A. (1985) Methods Enzymol., 115, 157-171.
7. Kadono, S., Sakurai, M., Moriyama, H., Sato, M., Hayashi, Y., Oshima, T., Tanaka, N. (1995) J. Biochem., 118, 745-752.
8. Kotsuka, K., Akanuma, S., Tomuro, M., Yamagishi, A. and Oshima, T. (1996) J. Bacteriol., 178, 723-727.
9. Kraulis, P.J. (1991) J. Appl. Crystallogr., 24, 946-950.
10. Laskowski, R.A., MacArthur, M.W., Moss, D.S. and Thornton, J.M. (1993) J. Appl. Crystallogr., 26, 283-291.
11. Matsumura, M., Becktel, W.J., Levitt, M. and Matthews, B.W. (1989) Nature, 334, 406-410
12. Matthews, B.W. (1968) J. Mol. Biol., 33, 491-497.
13. Nagata, C., Moriyama, H., Tanaka, N., Nakasako, M., Yamamoto, M., Ueki, T. and Oshima, J. (1996) Acta Crystallogr., D52, 623-630.
14. Otwinowski, Z. and Minor, W. (1997) Methods Enzymol., 276, 307-326.
15. Qu, C., Akanuma, S., Moriyama, H., Tanaka, N. and Oshima, T. (1997) Protein Engng, 10, 45-52.
16. Rhode, D.J. and Martin, B.L. (1999) Biochem. Biophys. Res. Commun., 258, 179-183.
17. Shortle, D. (1992) Q. Rev. Biophys., 25, 205-250.
18. Yamada, T., Akutsu, N., Miyazaki, K., Kakinuma, K., Yoshida, M. and Oshima, T. (1990) J. Biochem., 108, 449-456.
19. Yutani, K., Ogasahara, K., Tsujita, T. and Sugino, Y. (1987) Proc. Natl Acad. Sci. USA, 84, 4441-4444.
20. Závodszky, P., Kardos, J., Svingor, Á. and Petsko, G.A. (1998) Proc. Natl Acad. Sci. USA, 95, 7406-7411.