Differential actions of anandamide, potassium ions and endothelium- derived hyperpolarizing factor in guinea-pig basilar artery

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 361, Issue 5, 2000, Pages 535-542

  Zygmunt, Peter M ^a   Sørgård, Morten ^a   Petersson, Jesper ^a   Johansson, Rebecka ^a   Högestätt, Edward D ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Anandamide; Cerebral arteries; Endocannabinoids; Endothelium derived hyperpolarizing factor; Gap junctions; Na+ K+ ATPase; Potassium channels; Vascular endothelium

Indexed keywords

18ALPHA GLYCYRRHETINIC ACID; ACETYLCHOLINE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANANDAMIDE; APAMIN; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CHARYBDOTOXIN; CICLAZINDOL; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; GLIBENCLAMIDE; INDOMETACIN; N(G) NITROARGININE; OUABAIN; POTASSIUM ION; PROSTAGLANDIN F2 ALPHA; RESINIFERATOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASILAR ARTERY; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; COOLING; DOSE RESPONSE; ENZYME ACTIVITY; GAP JUNCTION; GUINEA PIG; HYPERPOLARIZATION; INCUBATION TIME; MALE; MEMBRANE STEADY POTENTIAL; NONHUMAN; SENSORY NERVE; SMOOTH MUSCLE FIBER; VASODILATATION;

ACETYLCHOLINE; ANIMALS; ARACHIDONIC ACIDS; BASILAR ARTERY; BIOLOGICAL FACTORS; CALCIUM CHANNEL BLOCKERS; CARDIOTONIC AGENTS; COLD; GAP JUNCTIONS; GUINEA PIGS; MALE; MEMBRANE POTENTIALS; NITRIC OXIDE; OUABAIN; POLYUNSATURATED ALKAMIDES; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; RECEPTORS, SENSORY; VASODILATION;

EID: 0034018029     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000229     Document Type: Article

References (49)

1. Brayden JE (1990) Membrane hyperpolarization is a mechanism of endothelium-dependent cerebral vasodilatation. Am J Physiol 259:H668-H673
2. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824
3. Chataigneau T, Félétou M, Thollon C, Villeneuve N, Vilaine J-P, Duhault J, Vanhoutte PM (1998) Cannabinoid CB1 receptor and endothelium-dependent hyperpolarization in guinea-pig carotid, rat mesenteric and porcine coronary arteries. Br J Pharmacol 123:968-974
4. Chaytor AT, Martin PEM, Evans WH, Randall MD, Griffith TM (1999) The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. J Physiol (Lond) 520:539-550
5. Davidson JS, Baumgarten IM (1988) Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships. J Pharmacol Exp Ther 246:1104-1107
6. Deutsch DG, Goligorski MS, Schmid PC, Krebsbach RJ, Schmid HHO, Das SK, Dey SK, Arreaza G, Thorup C, Stefano G, Moore LC (1997) Production and physiological actions of anandamide in the vasculature of the rat kidney. J Clin Invest 100:1538-1546
7. Di Marzo V, De Petrocellis L, Sepe N, Buono A (1996) Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. Biochem J 316:977-984
8. Docherty R, Yeats J, Bevan S, Boddeke H (1996) Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats. Pflugers Arch 431:828-837
9. Dora KA, Martin PEM, Chayator AT, Evans WH, Garland CJ, Griffith TM (1999) Role of heterocellular gap junctional communication in endothelium-dependent hyperpolarization: inhibition by a conenxin-mimetic peptide. Biochem Biophys Res Commun 254:27-31
10. Edwards G, Weston AH (1998) Endothelium-derived hyperpolarizing factor - a critical appraisal. Prog Drug Res 50:107-133
11. + is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 396:269-272
12. Edwards G, Feletou M, Gardener MJ, Thollon C, Vanhoutte PM, Weston AH (1999) Role of gap junctions in the responses to EDHF in rat and guinea-pig arteries. Br J Pharmacol 128: 1788-1794
13. Fimiani C, Mattocks D, Cavani F, Salzet M, Deutsch D, Pryor S, Bilfinger T, Stefano G (1999) Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: coupling to nitric oxide release. Cell Signal 11:189-193
14. Fissithaler B, Popp R, Kiss L, Potente M, Harder D, Fleming I, Busse R (1999) Cytochrome P450 2C is an EDHF synthase in coronary arteries. Nature 401:493-497
15. Franco-Cereceda A, Saria A, Lundberg JM (1989) Differential release of calcitonin gene-related peptide and neuropeptide Y from the isolated heart by capsaicin, ishaemia, nicotine, bradykinin and ouabain. Acta Physiol Scand 135:173-187
16. Hecker M, Bara A, Bauersachs J, Busse R (1994) Characterization of endothelium-derived hyperpolarizing factor as a cytochrome P450-derived arachidonic acid metabolite in mammals. J Physiol (Lond) 481:407-414
17. Högestätt ED, Andersson K-E, Edvinsson L (1983) Mechanical properties of rat cerebral arteries as studied by a sensitive device for recording of mechanical activity in isolated small blood vessels. Acta Physiol Scand 117:49-61
18. Högestätt ED, Petersson J, Andersson DA, Zygmunt PM (1999) Pharmacological characterization of the potassium channels targeted by endothelium-derived hyperpolarizing factor. In: Vanhoutte PM (ed) Endothelium-dependent hyperpolarization. Harwood Academic, Amsterdam, pp 217-227
19. Holzer P (1991) Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev 43: 143-201
20. Holzer P (1992) Peptidergic sensory neurons in the control of vascular functions: mechanisms and significance in the cutaneous and splanchnic vascular beds. Rev Physiol Biochem Pharmacol 121:50-146
21. 2+-induced relaxation. J Pharmacol Exp Ther 289:245-250
22. Kakuyama M, Vallance P, Ahluwalia A (1998) Endothelium-dependent sensory NANC vasodilatation: involvement of ATP, CGRP and a possible NO store. Br J Pharmacol 123:310-316
23. Li YJ, Duckles SP (1992) Effect of endothelium on the actions of sympathetic and sensory nerves in the perfused rat mesentery. Eur J Pharmacol 210:23-30
24. Ludbrook J (1994) Repeated measurements and multiple comparisons in cardiovascular research. Cardiovasc Res 28:303-311
25. Lundberg J (1996) Pharmacology of cotransmission in the autonomic nervous system: integrative aspects on amines, neuropeptides, adenosine triphosphate, amino acids and nitric oxide. Pharmacol Rev 48:113-178
26. Malmsjö M, Erlinge D, Högestätt E, Zygmunt P (1999) Endothelial P2Y receptors induce hyperpolarisation of vascular smooth muscle by release of endothelium-derived hyperpolarising factor. Eur J Pharmacol 364:169-173
27. Mombouli J, Vanhoutte P (1997) Endothelium-derived hyperpolarizing factor(s): updating the unknown. Trends Pharmacol Sci 18:252-256
28. 2+ in endotehlial cells. Br J Pharmacol 126:1593-1600
29. + channels. Nature 344:770-773
30. Nishiye E, Nakao K, Itoh T, Kuriyama H (1989) Factors inducing endothelium-dependent relaxation in the guinea-pig basilar artery as estimated from the actions of haemoglobin. Br J Pharmacol 96:645-655
31. Petersson J, Zygmunt PM, Brandt L, Högestätt ED (1995) Substance P-induced relaxation and hyperpolarization in human cerebral arteries. Br J Pharmacol 115:889-894
32. Petersson J, Zygmunt PM, Högestätt ED (1997) Characterization of the potassium channels involved in EDHF-mediated relaxation in cerebral arteries. Br J Pharmacol 120:1344-1350
33. 450 mono-oxygenase. J Vasc Res 35:285-294
34. Plane F, Holland M, Waldron GJ, Garland CJ, Boyle JP (1997) Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries. Br J Pharmacol 121: 1509-1511
35. Quignard J-F, Félétou M, Thollon C, Vilaine J-P, Duhault J, Vanhoutte PM (1999) Potassium ions and endothelium-derived hyperpolarizing factor in guinea-pig carotid and porcine coronary arteries. Br J Pharmacol 127:27-34
36. Ralevic V, Khalil Z, Dusting GJ, Helme RD (1992) Nitric oxide and sensory nerves are involved in the vasodilator response to acetylcholine but not calcitonin gene-related peptide in rat skin microvasculature. Br J Pharmacol 106:650-655
37. Randall MD, Kendall DA (1998) Anandamide and endothelium-derived hyperpolarizing factor act via a common vasorelaxant mechanism in rat mesentery. Eur J Pharmacol 346:51-53
38. Randall MD, Alexander SPH, Bennett T, Boyd EA, Fry JR, Gardiner SM, Kemp PA, McCulloch AI, Kendall DA (1996) An endogenous cannabinoid as an endothelium-derived vasorelaxant. Biochem Biophys Res Commun 229:114-120
39. Scott TM, Drodge KH, Foote J (1992) Peptidergic nerve involvement in the control of endothelium-dependent vascular relaxation. Artery 19:211-224
40. Szallasi A, Blumberg PM (1999) Vanilloid (capsaicin) receptors and mechanisms. Pharmacol Rev 51:159-212
41. Takenaga M, Kawasaki H, Wada A, Eto T (1995) Calcitonin gene-related peptide mediates acetylcholine-induced endothelium-independent vasodilation in mesenteric resistance blood vessels of the rat. Circ Res 76:935-941
42. Taylor HJ, Chaytor AT, Evans WH, Griffith TM (1998) Inhibition of the gap junctional component of endothelium-dependent relaxations in rabbit iliac artery by 18-alpha glycyrrhetinic acid. Br J Pharmacol 125:1-3
43. Vanheel B, Van de Voorde J (1999) Barium decreases endothelium-dependent smooth muscle responses to transient but not to more prolonged acetylcholine applications. Pflügers Arch 439:123-129
44. Wagner JA, Varga K, Jarai Z, Kunos G (1999) Mesenteric vasodilation mediated by endothelial anandamide receptors. Hypertension 33:429-434
45. White R, Hiley CR (1997) A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. Br J Pharmacol 122:1573-1584
46. Wood JN, Docherty R (1997) Chemical activators of sensory neurons. Annu Rev Physiol 59:457-482
47. Yamamoto Y, Imaeda K, Suzuki H (1999) Endothelium-dependent hyperpolarization and intercellular electrical coupling in guinea-pig mesenteric arterioles. J Physiol (Lond) 514:505-513
48. Zygmunt PM, Högestätt ED, Waldeck K, Edwards G, Kirkup AJ, Weston AH (1997) Studies on the effects of anandamide in rat hepatic artery. Br J Pharmacol 122:1679-1686
49. Zygmunt PM, Petersson J, Andersson DA, Chuang H-h, Sørg̊ard M, Di Marzo V, Julius D, Högestätt ED (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400:452-457