Breeding of a non-urea producing sake yeast with killer character using a kar1-1 mutant as a killer donor

Journal of Industrial Microbiology and Biotechnology

Volumn 24, Issue 3, 2000, Pages 203-209

  Yoshiuchi, K ^a   Watanabe, M ^a   Nishimura, A ^a  

^a Hakutsuru Sake Brewing Co Ltd   (Japan)

Author keywords

Kar1 1; Killer character; Non urea producing sake yeast; Protoplast fusion; Rare mating

Indexed keywords

ARGINASE; DNA; DOUBLE STRANDED RNA; UREA;

ARTICLE; BEVERAGE; CELL FUSION; CELL KILLING; CONTAMINATION; DNA CONTENT; FERMENTATION; FUNGUS MUTANT; MATING; NONHUMAN; PLASMID; PROTOPLAST; YEAST;

EID: 0034017633     PISSN: 13675435     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jim.2900797     Document Type: Article

References (44)

1. 1 Conde J and GR Fink. 1976. A mutant of Saccharomyces cerevisiae defective for nuclear fusion. Proc Natl Acad Sci USA 73: 3651-3655.
2. 2 Fink GR and CA Styles. 1972. Curing of a killer factor in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 69: 2846-2849.
3. 3 Fried HM and GR Fink. 1978. Electron microscopic heteroduplex analysis of 'killer' double-stranded RNA species from yeast. Proc Natl Acad Sci USA 75: 4224-4228.
4. 4 Hara S, K Yosizawa and K Nakamura. 1988. Formation of ethyl carbamate in model alcohol beverages containing urea or its related compounds. J Brew Soc Jpn 83: 57-63.
5. 5 Hara S, Y Iimura, H Oyama, T Kozeki, K Kitano and K Otsuka. 1981. The breeding of cryophillic killer wine yeast. Agric Biol Chem 45: 1327-1334.
6. 6 Imamura T, M Kawamoto and Y Takaoka. 1974. Characteristics of main mash infected by killer yeasts in sake brewing and the nature of its killer factor. J Ferment Technol 52: 293-299.
7. 7 Javadekar VS, H SivaRaman and DV Gokhale. 1995. Industrial yeast strain improvement: construction of a highly flocculent yeast with a killer character by protoplast fusion. J Ind Microbiol 15: 94-102.
8. 8 Kitamoto K, K Oda, K Gomi and K Takahashi. 1991. Genetic engineering of a sake yeast producing no urea by successive disruption of arginase gene. Appl Environ Microbiol 57: 301-306.
9. 9 Kitamoto K, K Oda-Miyazaki, K Gomi and C Kumagai. 1993. Mutant isolation of non-urea producing sake yeast by positive selection. J Ferment Bioeng 75: 359-363.
10. 10 Kobashi K, S Takebe and T Sakai. 1988. Removal of urea from alcoholic beverages with an acid urease. J Appl Toxicol 8: 73-74.
11. 11 Littlewood BS. 1975. Methods for selecting auxotrophic and temperature-sensitive mutants in yeasts. In: The Method in Cell Biology Vol 11 (Prescott DM, ed), pp 273-285, Academic Press, New York.
12. 12 Matsumoto K, Y Adach, A Toh-e and Y Oshima. 1980. Function of positive regulatory gene gal4 in the synthesis of galactose pathway enzymes in Saccharomyres cerevisiae: evidence that the GAL81 region codes for part of the gal4 protein. J Bacteriol 141: 508-527.
13. 13 Middelhoven WJ. 1964. The pathway of arginine breakdown in Saccharomyces cerevisiae. Biochim Biophys Acta 93: 650-652.
14. 14 Mirvish SS. 1968. The carcinogenic action and metabolism of urethan and N-hydroxyurethan. Adv Cancer Res 11: 1-42.
15. 15 Miyagawa K, M Sumida, M Nakao, M Harada, H Yamamoto, T Kusumi, K Yoshizawa, T Amachi and T Nakayama. 1999. Purification, characterization, and application of an acid urease from Arthrobacter mobilis. J Biotechnol 68: 227-236.
16. 16 Monterio FF, E Trounsdale and LF Bisson. 1989. Ethyl carbamate formation in wine: use of radioactively labeled precursors to demonstrate the involvement of urea. Am J Enol Vitic 40: 1-8.
17. 17 Nakazawa N, T Ashikari, N Goto, T Amachi, R Nakajima, S Harashima and Y Oshima. 1992. Partial restoration of sporulation defect in sake yeast, Kyokai no. 7 and no. 9, by increased dosage of the IMEI gene. J Ferment Bioeng 73: 265-270.
18. 18 Nishiya T (ed). 1993. National Tax Administration, Japan Prescript Analysis Methods with Note (4th edn), pp 7-33, Brewing Society of Japan, Tokyo.
19. 19 Nishiya T, T Ishikawa and Y Iimura. 1984. Breeding of adenine auxotrophic killer mutants of sake yeast: making of a new type of pink colored sake using an adenine auxotroph of sake yeast. J Brew Soc Jpn 79: 886-890.
20. 20 Ouchi K and H Akiyama. 1976. Breeding of useful killer sake yeast by repeated back-crossing. J Ferment Technol 54: 615-623.
21. 21 Ouchi K, RB Wickner, A Toh-e and H Akiyama. 1979. Breeding of killer yeasts for sake brewing by cytoduction. J Ferment Technol 57: 483-487.
22. 22 Ouchi K, T Nishiya and H Akiyama. 1983. UV-killed protoplast fusion as a method for breeding killer yeasts. J Ferment Technol 61: 631-635.
23. 23 Ough CS. 1976. Ethyl carbamate in fermented beverages and foods. I. Naturally occurring ethyl carbamate. J Agric Food Chem 24: 323-328.
24. 24 Ough CS, EA Crowell and BR Gutlove. 1988. Carbamyl compound reactions with ethanol. Am J Enol Vitic 39: 239-249.
25. 25 Ough CS and G Trioli. 1988. Urea removal from wine by an acid urease. Am J Enol Vitic 39: 303-307.
26. 26 Ough CS, D Stevens, T Sendovski, Z Huang and D An. 1990. Factors contributing to urea formation in commercially fermented wines. Am J Enol Vitic 41: 68-73.
27. 27 Riffkin HL, R Wilson and TA Bringhurst. 1989. Ethyl carbamate formation in the production of pot still whisky. J Inst Brew 95: 115-119.
28. 28 Salek A, R Schnettler and U Zimmermann. 1990. Transmission of killer activity into laboratory and industrial strains of Saccharomyces cerevisiae by electroinjection. FEMS Microbiol Lett 70: 67-72.
29. 29 Salek A, R Schnettler and U Zimmermann. 1992. Stably inherited killer activity in industrial yeast strains obtained by electrotransformation. FEMS Microbiol Lett 96: 103-109.
30. 30 Segal M. 1988. Too Many Drinks Spiked with Urethane. FDA Consumer April: 16-17.
31. 31 Shimoda M, H Mizoguchi and E Fuzita. 1984. Breeding of killer-resistant sake yeasts (neutral) using the miniprotoplast fusion method. J Brew Soc Jpn 79: 349-354.
32. 32 Spencer JFT and DM Spencer. 1977. Hybridization of non-sporulating and weakly sporulating strains of brewer's and distiller's yeast. J Inst Brew 83: 287-289.
33. 33 Steven B and DJ Lew. 1997. Flow cytometric analysis of DNA content in budding yeast. Meth Enzymol 283: 322-332.
34. 34 Suizu T, Y Iimura, K Gomi, K Takahashi, S Hara, K Yosizawa and G Tanuma. 1990. Construction of urea non-producing yeast Saccharomyces cerevisiae by disruption of the CARI gene. Agric Biol Chem 54: 537-539.
35. 35 Suizu T. 1996. Studies on sporulation of sake yeast. Seibutsu-kogaku 74: 115-123.
36. 36 Sumrada RA and TG Cooper. 1982. Isolation of the CARI gene from Saccharomyces cerevisiae and analysis of its expression. Mol Cell Biol 2: 1514-1523.
37. 37 Tanaka N, H Nagai, E Nakazawa, H Mishima and S Takemura. 1989. Isolation of mutants having low carbamide-producing ability from sake yeast. J Brew Soc Jpn 84: 413-417.
38. 38 Trioli G and CS Ough. 1989. Cause for inhibition of an acid urease from Lactobacillus fermentum. Am J Enol Vitic 40: 245-252.
39. 39 Wickner RB. 1974. 'Killer character' of Saccharomyces cerevisiae: curing by growth at elevated temperature. J Bacteriol 117: 1356-1357.
40. 40 Whitney PA and B Magasanik. 1973. The induction of arginase in Saccharomyces cerevisiae. J Biol Chem 248: 6197-6202.
41. 41 Yamamoto T, J Yagiu, K Ohta, M Hamano, K Ouchi and T Nishiya. 1984. Breeding of an alcohol yeast with K2 type killer plasmids and its application to continuous alcohol fermentation. Nippon Nogeikagaku Kaishi 58: 559-566.
42. 42 Yoshizawa K and K Takahashi. 1988. Utilization of ureases for urea decomposition in sake. J Brew Soc Jpn 83: 142-144.
43. 43 Young TW. 1981. The genetic manipulation of killer character into brewing yeast. J Inst Brew 87: 292-295.
44. 44 Young TW. 1987. killer yeasts. In: The Yeast, Vol 2 (Rose AH and JS Harrison, eds). pp 131-164, Academic Press, London.