Nucleotides -1 to -4 of hepatitis delta ribozyme substrate increase the specificity of ribozyme cleavage

Antisense and Nucleic Acid Drug Development

Volumn 10, Issue 1, 2000, Pages 53-61

  Deschênes, Patrick ^a   Lafontaine, Daniel A ^a   Charland, Stéphanie ^a   Perreault, Jean Pierre ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOZYME; VIRUS ENZYME; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; ENZYME SPECIFICITY; HEPATITIS DELTA VIRUS; KINETICS; NONHUMAN; PRIORITY JOURNAL; RNA CLEAVAGE; RNA SEQUENCE;

DELTA VIRUS; HEPATITIS DELTA VIRUS;

EID: 0034017517     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.2000.10.53     Document Type: Article

References (25)

1. ANANVORANICH, S., LAFONTAINE, D.A., and PERREAULT, J.-P. (1999). Mutational analysis of the antigenomic trans-acting delta ribozyme: The alterations of the middle nucleotides located on the P1 stem. Nucleic Acids Res. 27, 1473-1479.
2. ANANVORANICH, S., and PERREAULT, J.P. (1998). Substrate specificity of δ ribozyme cleavage. J. Biol. Chem. 273, 13182-13188.
3. BEEN, M.D., PERROTTA, A.T., and ROSEINSTEIN, S. (1992). Secondary structure of the self-cleaving RNA of hepatitis delta virus ribozyme: Applications to catalytic RNA design. Biochemistry 31, 11843-11852.
4. BEEN, M.D., and WICKHAM, G.S. (1997). Self-cleaving ribozymes of hepatitis delta virus RNA. Eur. J. Biochem. 247, 741-753.
5. BRAVO, C., LESCURE, F., LAUGAA, P., FOURREY, J.L., and FAVRE, A. (1996). Folding of the HDV antigenomic ribozyme pseudoknot structure deduced from long-range photocrosslinks. Nucleic Acids Res. 24, 1351-1359.
6. DAVANOO, P., ROSENBERG, A.H., DUNN, J.J., and STUDIER, F.W. (1984). Cloning and expression of the gene for bacteriophage T7 RNA polymerase. Proc. Natl. Acad. Sci. USA 81, 2035-2039.
7. FERRÉ-D'AMARÉ, A.R., ZHOU, K., and DOUDNA, J.A. (1998). Crystal structure of a hepatitis delta virus ribozyme. Nature 395, 399-404.
8. KAWAKAMI, J., YADA, K., SUM, Y.A., KUMAR, P.K.R., NISHIKAWA, F., MAEDA, H., TAIRA, K., OHTSUKA, E., and NISHIKAWA, S. (1996). Constructing an efficient trans-acting genomic HDV ribozyme. FEBS Lett. 394, 132-136.
9. KUMAR, P.K.R., SUH, Y.A., TAIRA, K., and NISHIKAWA, S. (1993). Point and compensation mutations to evaluate essential stem structures of genomic HDV ribozyme. FASEB J. 7, 124-128.
10. MERCURE, M., LAFONTAINE, D., ROY, G., and PERREAULT, J.P. (1997). Le motif autocatalytique d'ARN du virus delta de l'hepatitie humaine. Med. Sci. 13, 662-669.
11. MERCURE, S., LAFONTAINE, D., ANANVORANICH, S., and PERREAULT, J.P. (1998). Kinetic analysis of δ ribozyme cleavage. Biochemistry 37, 16975-16982.
12. NISHIKAWA, F., FAUZI, H., and NISHIKAWA, S. (1997). Detailed analysis of base preferences at the cleavage site of a trans-acting HDV ribozyme: A mutation that changes cleavage site specificity. Nucleic Acids Res. 25, 1605-1610.
13. NISHIKAWA, F., ROY, M., FAUZI, H., and NISHIKAWA, S. (1999). Detailed analysis of stem I and its 5′ and 3′ neighbor regions in the trans-acting HDV ribozyme. Nucleic Acids Res. 27, 403-410.
14. PERREAULT, J.P., and ALTMAN, S. (1992). Important 2′-hydroxyl groups in model substrates for Ml RNA, the catalytic RNA subunit of RNase P from Escherichia coli. J. Mol. Biol. 226, 399-409.
15. PERROTTA, A.T., and BEEN, M.D. (1991). A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA. Nature 350, 434-436.
16. PERROTTA, A.T., and BEEN, M.D. (1992). Cleavage of oligoribonucleotides by a ribozyme derived from the hepatitis 5 virus RNA sequence. Biochemistry 31, 16-21.
17. ROY, G., ANANVORANICH, S., and PERREAULT, J.P. (1999). Delta ribozyme has the ability to cleave in trans an mRNA. Nucleic Acids Res. 27, 942-948.
18. TRAUT, T.W. (1994). Physiological concentrations of purines and pyrimidines. Mol. Cell. Biochem. 140, 1-22.
19. VARANI, G. (1995). Exceptionally stable nucleic acid hairpins. Annu. Rev. Biophys. Biomol. Struct. 24, 379-404.
20. WADKINS, T.S., PERROTTA, A.T., FERRÉ-D'AMARÉ, A.R., DOUDNA, J.A., and BEEN, M.D. (1999). A nested double pseudoknot is required for self-cleavage activity of both the genomic and antigenomic hepatitis delta virus ribozymes. RNA 5, 720-727.
21. WU, H.N., and HUANG, Z.S. (1992). Mutagenesis analysis of the self-cleavage domain of hepatitis delta virus antigenomic RNA. Nucleic Acids Res. 20, 5937-5941.
22. WU, H.N., LEE, J.Y., HUANG, H.W., HUANG, Y., and HSUEH, T.G. (1993). Mutagenesis analysis of a hepatitis delta virus genomic ribozyme. Nucleic Acids Res. 21, 4193-4199.
23. WU, H.N., LIN, Y.J., LIN, F.P., MAKINO, S., CHANG, M.F., and LAI, M. (1989). Human hepatitis 5 virus RNA subfragments contain an autocleavage activity. Proc. Natl. Acad. Sci. USA 86, 1831-1835.
24. WU, H.N., WANG, Y.J., HUNG, C.F., LEE, H.J., and LAI, M.M.C. (1992). Sequence and structure of the catalytic RNA of hepatitis delta virus genomic RNA. J. Mol. Biol. 223, 233-245.
25. ZAWADZKI, V., and GROSS, H.J. (1991). Rapid and simple purification of T7 RNA polymerase. Nucleic Acids Res. 19, 1948.