Phase variation of the gonococcal siderophore receptor FetA

Molecular Microbiology

Volumn 36, Issue 3, 2000, Pages 585-593

  Carson, Susan D Biegel ^a   Stone, Barbara ^a   Beucher, Margaret ^b   Fu, Jennifer ^a   Sparling, P Frederick ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; CELL SURFACE RECEPTOR; CYTOSINE; SIDEROPHORE;

ANTIGEN EXPRESSION; ANTIGENIC VARIATION; ARTICLE; CONTROLLED STUDY; NEISSERIA GONORRHOEAE; NONHUMAN; PRIORITY JOURNAL;

ALKALINE PHOSPHATASE; BACTERIAL OUTER MEMBRANE PROTEINS; BASE SEQUENCE; CYCLIN-DEPENDENT KINASES; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; NEISSERIA GONORRHOEAE; POLY C; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); RECEPTORS, CELL SURFACE; RECOMBINANT FUSION PROTEINS;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEISSERIA GONORRHOEAE;

EID: 0034017347     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2000.01873.x     Document Type: Article

References (34)

1. Ala'Aldeen, D.A., Davies, H.A., and Borriello, S.P. (1994) Vaccine potential of meningoccal FrpB: studies on surface exposure and functional attributes of common epitopes. Vaccine 12: 535-541.
2. Belland, R.J., Morrison, S.G., van der Ley, P., and Swanson, J. (1989) Expression and phase variation of gonococcal P.II genes in Escherichia coli involves ribosomal frameshifting and slipped-strand mispairing. Mol Microbiol 3: 777-786.
3. Black, J.R., Dyer, D.W., Thompson, M.K., and Sparling, P.F. (1986) Human immune response to iron-repressible outer membrane proteins of Neisseria meningitidis. Infect Immun 54: 710-713.
4. Carson, S.D.B., Klebba, P.E., Newton, S.M.C., and Sparling, P.F. (1999) Ferric enterobactin binding and utilization by Neisseria gonorrhoeae. J Bacteriol 181: 2895-2901.
5. Case, C.C., Roels, S.M., Gonzalez, J.E., Simons, E.L., and Simons, R.W. (1988) Antisense RNA: prokaryotic controls: analysis of the promoters and transcripts involved in IS 10 antisense RNA control. Gene 72: 219-236.
6. Chen, C.-J., Elkins, C., and Sparling, P.F. (1998) Phase variation of hemoglobin utilization in Neisseria gonorrhoeae. Infect Immun 66: 987-993.
7. Cornelissen, C.N., Kelley, M., Hobbes, M.M., Anderson, J.E., Cannon, J.G., Cohen, M.S., et al. (1998) The transferrin receptor expressed by gonococcal strain FA1090 is required for the experimental infection of human male volunteers. Mol Microbiol 27: 611-616.
8. Danaher, R.J., Levin, J.C., Arking, D., Burch, C.L., Sandlin, R., and Stein, D.C. (1995) Genetic basis of Neisseria gonorrhoeae lipooligosaccharide antigenic variation. J Bacteriol 177: 7275-7279.
9. Dyer, D.W., West, E.P., McKenna, W., Thompson, S.A., and Sparling, P.F. (1988) A pleiotropic iron-uptake mutant of Neisseria meningitidis lacks a 70-Kilodaltan iron-regulated protein. Infect Immun 56: 977-983.
10. van der Ende, A., Hopman, C.T.P., Zaat, S., Essink, B.B.O., Berkhout, B., and Dankert, J., (1995) Variable expression of class 1 outer membrane protein in Neisseria meningitidis is caused by variation in the spacing between the -10 and -35 regions of the promoter. J Bacteriol 177: 2475-2480.
11. Gunn, J.S., and Stein, D.C. (1996) Use of a non-selective transformation technique to construct a multiply restriction/ modification-deficient mutant of Neisseria gonorrhoeae. Mol Gen Genet 251: 509-517.
12. Hammerschmidt, S., Muller, A., Sillmann, H., Muhlenhoff, M., Borrow, R., Fox, A., et al. (1996) Capsule phase variation in Neisseria meningitidis serogroup B by slipped-strand mispairing in the polysialyltransferase gene, (siaD): correlation with bacterial invasion and the outbreak of meningococcal disease. Mol Microbiol 20: 1211-1220.
13. Hobbs, M.M., Alcorn, T.M., Davis, R.H., Fischer, W., Thomas, J.C., Martin, I., et al. (1999) Molecular typing of Neisseria gonorrhoeae causing repeated infections: evolution of porin during passage within a community. J Infect Dis 179: 371-381.
14. Inoue, T., and Cech, T.R. (1985) Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase. Proc Natl Acad Sci USA 82: 648-652.
15. Inoue, H., Nojima, H., and Okayama, H., (1990) High efficiency transformation of Escherichia coli with plasmids. Gene 96: 23-28.
16. Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, B.B., Fauci, A.S., and Kaspar, D.L. (eds.) (1994) Laboratory values of clinical importance. In Harrison's Principles of Internal Medicine, New York: McGraw-Hill, pp. 2490.
17. Kellogg, Jr, D.S. Peacock, Jr, W.L. Deacon, W.E., Brown, L., and Pirkle, C.I. (1963) Neisseria gonorrhoeae. I. Virulence genetically linked to clonal variation. J Bacteriol 85: 1274-1279.
18. Kreuzer, K., Pratt, C., and Torriani, A. (1975) Genetic analysis of regulatory mutants of alkaline phosphatase of E. coli. Genetics 81:459-468.
19. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
20. Levinson, G., and Gutman, G.A. (1987) Slipped-strand mispairing: a major mechanism for DNA sequence evolution. Mol Biol Evol 4: 203-221.
21. van der Ley, P., van der Biezen, J., Sutmuller, R., Hoogerhout, P., and Poolman, J.T. (1996) Sequence variability of FrpB, a major iron-regulated outer-membrane protein in the pathogenic neisseriae. Microbiology 142: 3269-3274.
22. Maness, M.J., and Sparling, P.F. (1973) Multiple antibiotic resistance due to a single mutation in Neisseria gonorrhoeae. J Infect Dis 128: 321-330.
23. Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
24. Mulligan, M.E., Brosius, J., and McClure, W.R. (1985) Characterization of the effect of spacer legnth on the effect of Escherichia coli RNA polymerase at the TAC promoter. J Biol Chem 260: 3529-3538.
25. Murphy, G.L., Connel, T.D., Barritt, D.S., Koomey, M., and Cannon, J.G. (1989) Phase variation of gonococcal protein II: regulation of gene expression by slipped-strand mispairing of a repetitive DNA sequence. Cell 56: 539-547.
26. Nachamkin, I., Cannon, J.G., and Mittler, R.S., (1981) Monoclonal antibodies against Neisseria gonorrhoeae: production of antibodies directed against a strain-specific cell surface antigen. Infect Immun 33: 555-564.
27. 70) promoters, and the kinetics of the steps of transcription initiation, In Escherichia Coli and Salmonella: Cellular and Molecular Biology. Neidhardt, F.C. (ed. ). Washington, DC: American Society for Microbiology Press, pp. 792-820.
28. Richardson, A.R., and Stojiljkovic, I. (1999) HmbR, a hemoglobin-binding outer membrane protein of Neisseria meningitidis, undergoes phase variation. J Bacteriol 181: 2067-2074.
29. Sarkari, J., Pandit, N., Moxon, E.R., and Achtman, M. (1994) Variable expression of the Opc outer membrance protein in Neisseria meningitidis is caused by size variattion of a promoter containing poly-cytidine. Mol Microbiol 13: 207-217.
30. Thomas, C.E., and Sparling, P.F. (1996) Isolation and analysis of a fur mutant of Neisseria gonorrhoeae. J Bacteriol 178: 4224-4232.
31. Thomas, C.E., Carbonetti, N.H., and Sparling, P.F. (1996) Pseudo-transposition of a Tn5 derivative in Neisseria gonorrhoeae. FEMS Microbiol Lett 145: 371-376.
32. Towbin, J., Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrilamide gels to nitrocellulose sheets: procedures and some applications. Proc Natl Acad Sci USA 76: 4350-4354.
33. West, S.E.H., and Sparling, P.F. (1985) Response of Neisseria gonorrhoeae to iron limitation: alterations in expression of membrane proteins without apparent siderophore production. Infect Immun 47: 388-394.
34. Yang, Q.L., and Gotschlich, E.C. (1996) Varaition of gonococcal lipooligosaccharide structure is due to alterations in poly-G tracts in lgt genes encoding glycosyl transferases. J Exp Med 183: 323-327.