Isolation and characterization of a novel soil strain, Pseudomonas cepacia BY21, with glutaryl-7-aminocephalosporanic acid acylase activity

Biotechnology Letters

Volumn 22, Issue 4, 2000, Pages 317-320

  Khang, Yong Ho ^a   Yoo, Byong Hoon ^a  

^a Yeungnam University   (South Korea)

Author keywords

7 aminocephalosporanic acid; Bioconversion; Cephalosporin C; Glutaryl 7 ACA acylase

Indexed keywords

AMIDASE; ANILIDE; CEPHALOSPORANIC ACID DERIVATIVE;

ARTICLE; BACTERIUM ISOLATION; BIOASSAY; BURKHOLDERIA CEPACIA; COLORIMETRY; CONTROLLED STUDY; ENTEROBACTER; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; SOIL; THIN LAYER CHROMATOGRAPHY;

PSEUDOMONAS CEPACIA;

EID: 0034017130     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005643020744     Document Type: Article

References (10)

1. Aramori I, Fukagawa M, Tsumura M, Iwami M, Ono H, Kojo H, Kohsaka M, Ueda Y, Imanaka H (1991) Cloning and nucleotide sequencing of a novel 7β-(4-carboxybutanamido)cephalosporanic acid acylase gene of Bacillus laterosporus and its expression in Escherichia coli and Bacillus subtilis. J. Bacteriol. 173: 7848-7855.
2. Aramori I, Fukagawa M, Tsumura M, Iwami M, Ono H, Ishitani Y, Kojo H, Kohsaka M, Ueda Y, Imanaka H (1992) Comparative characterization of new glutaryl-7-ACA and cephalosporin C acylases. J. Ferment. Bioeng. 73: 185-192.
3. Binder RG, Numata K, Lowe DA, Murakami T, Brown JL (1993) Isolation and characterization of a Pseudomonas strain producing glutaryl-7-aminocephalosporanic acid acylase. Appl. Environ. Microbiol. 59: 3321-3326.
4. Conlon HD, Baqai J, Baker K, Shen YQ, Wong BL, Noiles R, Rausch CW (1995) Two-step immobilized enzyme conversion of cephalosporin C to 7-aminocephalosporanic acid. Biotechnol. Bioeng. 46: 510-513.
5. Franzosi G, Battistel E, Gagliardi I, Van der Goes W (1995) Screening and characterization of microorganisms with glutaryl-7ADCA acylase activity. Appl. Microbiol. Biotechnol. 43: 508-513.
6. Ishiye M, Niwa M (1992) Nucleotide sequence and expression in Escherichia coli of the cephalosporin acylase gene of a Pseudomonas strain. Biochim. Biophys. Acta 1132: 233-239.
7. Pollegioni L, Molla G, Campaner S, Martegani E, Pilone MS (1997) Cloning, sequencing and expression in E. coli of a D-amino acid oxidase cDNA from Rhodotorula gracilis active on cephalosporin C. J. Biotechnol. 58: 115-123.
8. Saito Y, Fujimura T, Ishii Y, Noguchi Y, Miura T, Niwa M, Shimomura K (1996) Oxidative modification of a cephalosporin C acylase from Pseudomonas strain N176 and site-directed mutagenesis of the gene. Appl. Environ. Microbiol. 62: 2919-2925.
9. Shewale JG, Kumar KK, Ambekar GR (1987) Evaluation of determination of 6-aminopenicillanic acid by p-dimethylaminobenzaldehyde. Biotechnol. Tech. 1: 69-72.
10. Sonawane VC, Jolly RS, Vohra RM (1996) Cephalosporin modification: An extracellular glutaryl-7-ACA acylase from Bacillus sp. Biotechnol. Lett. 18: 965-968.