Associations of the collagen type Iα1 Sp1 polymorphism with five-year rates of bone loss in older adults

Calcified Tissue International

Volumn 66, Issue 4, 2000, Pages 268-271

  Harris, S S ^a   Patel, M S ^b   Cole, D E C ^b   Dawson Hughes, B ^a  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1;

ADULT; AGED; ALLELE; ARTICLE; BONE ATROPHY; BONE DENSITY; BONE MINERAL; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OSTEOPOROSIS; PATHOLOGIC FRACTURE; PRIORITY JOURNAL;

EID: 0034016471     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005842     Document Type: Article

References (11)

1. Grant SF, Reid DM, Blake G, Herd R, Fogelman I, Ralston SH (1996) Reduced bone density and osteoporosis associated with a polymorphic Sp 1 binding site in the collagen type I alpha 1 gene. Nat Genet 14:203-205
2. Garnero P, Borel O, Grant SFA, Ralston SH, Delmas PD (1998) Collagen Iαl Spl polymorphism, bone mass, and bone turnover in healthy French premenopausal women: the OFELY study. J Bone Miner Res 13:813-817
3. Uitterlinden AG, Burger H, Huang Q, Yue F, McGuigan FEA, Grant SFA, Hofman A, van Leeuwen JPTM, Pols HAP, Ralston SH (1998) Relation of alleles of the collagen type Iαl gene to bone density and trie risk of osteoporotic fractures in postmenopausal women. N Engl J Med 338:1016-1021
4. Roux C, Dougados M, Abel L, Mercier G, Lucotte G (1998) Association of a polymorphism in the collagen Iαl gene with osteoporosis in French women (Letter) Arthritis Rheum 41: 187-188
5. Willing MC, Torner JC, Burns TL, Segar ET, Werner JR (1997) Determinants of bone mineral density in postmenopausal white Iowans. J Geront, series A, Biol Sci Med Sci 52:M337-342
6. Langdahl BL, Ralston SH, Grant SFA, Eriksen E (1998) An Spl binding site polymorphism in the COLIAl gene predicts osteoporotic fractures in both men and women. J Bone Miner Res 13:1384-1389
7. Dawson-Hughes B, Harris SS, Krall EA, Dallal G (1997) Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 337:670-676
8. Johnson J, Dawson-Hughes B (1991) Precision and stability of dual-energy x-ray absorptiometry measurements. Calcif Tissue Int 49:174-178
9. Washburn RA, Smith KW, Jette AM, Janney CA (1993) The physical activity scale for the elderly (PASE): development and evaluation. J Clin Epidemiol 46:153-162
10. Garnero P, Borel O (1997) SpI binding site polymorphism in the collagen type Iαl gene, peak bone mass, postmenopausal bone loss, and bone turnover: the OFELY study (abstract) J Bone Miner Res 12:S490
11. Heegaard AM, Jorgensen HL, Vestergaard AW, Hassager C, Grant SFA, Ralston SH (1998) Lack of influence of SpI polymorphism in the collagen type Iαl gene on the rate of bone loss in postmenopausal women followed for 18 years (abstract) Bone 23:S373.