Genetically and epidemiologically related 'non-syncytium-inducing' isolates of HIV-1 display heterogeneous growth patterns in macrophages

Journal of Medical Virology

Volumn 61, Issue 2, 2000, Pages 171-180

  Aquino De Jesus, Mary Janette ^a   Anders, Cynthia ^c   Miller, George ^a,b   Sleasman, John W ^c   Goodenow, Maureen M ^c   Andiman, Warren A ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Dual tropism; Monocyte derived macrophages; Non syncytium inducing; Pediatric HIV infection; Viral isolates; Viral phenotype

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DISEASE MARKER; FEMALE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; NONHUMAN; PHENOTYPE; PILOT STUDY; PRESCHOOL CHILD; SEQUENCE ANALYSIS; VIRAL GENETICS; VIROGENESIS; VIRUS ISOLATION; VIRUS REPLICATION;

ADULT; AMINO ACID SEQUENCE; ANTIGENS, CD4; ANTIGENS, VIRAL; CELL LINE; CELLS, CULTURED; CHILD, PRESCHOOL; FEMALE; GIANT CELLS; HIV CORE PROTEIN P24; HIV INFECTIONS; HIV-1; HUMANS; INFANT; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MOLECULAR SEQUENCE DATA; PHENOTYPE; PROSPECTIVE STUDIES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CHEMOKINE; TRANSFECTION; TROPISM; U937 CELLS; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0034015997     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9071(200006)61:2<171::AID-JMV1>3.0.CO;2-X     Document Type: Article

References (39)

1. Alkhatib G, Broder CC, Berger EA. 1996. Cell type-specific co-factors determine human immunodeficiency virus type 1 tropism for T-cell lines versus primary macrophages. J Virol 70:5487-5494.
2. Alkhatib G, Liao F, Berger BA, Farber JM, Peden KW. 1997. A new SIV co-receptor, STRL 33. Nature 388:238-242.
3. Anders C, Aquino de Jesus MJ, Miller G, Sleasman JW, Andiman WA, Goodenow MM. 1998. Replicative levels of primary HIV-1 isolates in monocyte-derived macrophages (MDM) provide a marker for pathogenesis of M-tropic viruses. Abstract 573. In: Fifth conference on retroviruses and opportunistic infections. Chicago, IL.
4. Borkowsky W, Krasinski K, Cao Y, Ho D, Pollack H, Moore T, Chen SH, Allen M, Tao PT. 1994. Correlation of perinatal transmission of human immunodeficiency type 1 with maternal viremia and lymphocyte phenotypes. J Pediatr 125:345-351.
5. Centers for Disease Control and Prevention. 1994 Revised classification system for human immunodeficiency virus infection in children less than 13 years of age. MMWR 1994;43:No. RR12, 1-19.
6. + T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals. J Virol 67:1772-1777.
7. Dahl K, Martin K, Miller G. 1987. Differences among HIV strains in their capacity to induce cytolysis or persistent infection of a lymphoblastoid cell line immortalized by Epstein-Barr virus. J Virol 61:1602-1608.
8. Deng H, Liu R, Ellmeier W, Choe S, Unutmaz S, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Hill CM, Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR. 1996. Identification of a major co-receptor for primary isolates of HIV-1. Nature 381:661-666.
9. DeRossi A, Pasti M, Mammano F, Ometto L, Giaquinto C, Chieco-Bianchi L. 1991. Perinatal infection by human immnodeficiency virus type 1 (HIV-1): relationship between proviral copy number in vivo, viral properties in vitro, and clinical outcome. J Med Virol 35:283-289.
10. DeRossi A, Giaquinto C, Ometto L, Mammano F, Zanotto C, Dunn D, Chieco-Bianci L. 1993. Replication and tropism of human immunodeficiency virus type 1 as predictors of disease outcome in infants with vertically acquired infection. J Pediatr 123:929-936.
11. Dittmar MT, McKnight A, Simmons G, Clapham PR, Weiss RA, Simmonds P. 1997. HIV-1 tropism and co-receptor use. Nature 385: 495-496.
12. Doms RW, Peipert SC. 1997. Unwelcomed guests with master keys: how HIV uses chemokine receptors for cellular entry. Virology 235:179-190.
13. Ezekowitz AB, Kulhman M, Groopman JE, Byrn RA. 1989. A human serum mannose-binding protein inhibits in vitro infection by the human immunodeficiency virus. J Exp Med 169:185-196.
14. Fitzgibbon JE, Gaur S, Gavai M, Gregory P, Frenkel LD, John JF Jr. 1998. Effect of the HIV-1 syncytium-inducing phenotype on disease stage in vertically-infected children. J Med Virol 55:56-63.
15. Groenink M, Foudnier RAM, Broersen S, Baker CH, Koot M, van't Wout AB, Huisman HG, Miedema F, Tersmette M, Schuitemaker H. 1993. Relation of phenotype evolution of HIV-1 to envelope V2 configuration. Science 260:1513-1516.
16. Hansen JES, Nielsen C, Mathiesen LR, Nielsen JO. 1991. Involvement of lymphocyte function-associated antigen-1 (LFA-1) in HIV infection: inhibition by monoclonal antibody. Scand J Infect Dis 23:31-36.
17. Ho DD, Rota TR, Hirsch MS. 1986. Infection of monocyte/ macrophages by human T-lymphotropic virus type III. J Clin Invest 77:1712-1715.
18. Ikeda MK, Andiman WA, Mezger JL, Shapiro ED, Miller G. 1993. Quantitative leukoviremia and immune complex-dissociated anti-genemia as predictors of infection status in children born to mothers infected with HIV-1. J Pediatr 122:524-531.
19. Jurriaans S, Van Gemen B, Weverling GJ, Van Strijp D, Nara P, Coutinho R, Koot M, Schuitemaker H, Goudsmit J. 1994. The natural history of HIV-1 infection: virus load and virus phenotype independent determinants of clinical course? Virology 204:223-233.
20. Koot M, Vos AHV, Keet RPM, de Goede REY, Dercksen MW, Terpstra FG, Coutinho RA, Miedema F, Tersmette M. 1992. HIV-1 biological phenotype in long-term infected individuals evaluated with an MT-2 cocultivation assay. AIDS 6:49-54.
21. Landau NR, Littman DR. 1992. Packaging system for rapid production of murine leukemia virus vectors with variable tropism. J Virol 66:5110-5113.
22. Levy JA, Shimabukuro J, McHugh T, Casavant C, Stites D, Oshiro L. 1985. AIDS-associated retroviruses (ARV) can productively infect other cells besides human T helper cells. Virology 147:441-448.
23. Littman DR. 1998. Chemokine receptors: keys to AIDS pathogenesis? Cell 93:677-680.
24. Popovic M, Sarngadharan MG, Read E, Gallo RC. 1994. Detection, isolation and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 244: 497-500.
25. Ralph P, Moore MAS, Nilsson K. 1976. Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines. J Exp Med 143:1528-1533.
26. Rizzuto CD, Sodroski JG. 1997. Contribution of virion 1CAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization. J Virol 71:4847-4851.
27. Sabri F, Chiodi F, Fenyo EM. 1996. Lack of correlation between V3 amino acid sequence and syncytium-inducing capacity of some HIV type 1 isolates. AIDS Res Hum Retro 12:855-858.
28. Sakai K, Dewhurst S, Ma X, Volsky DJ. 1988. Differences in cytopathogenicity and host cell range among infectious molecular clones of human immunodeficiency virus type 1 simultaneously isolated from an individual. J Virol 62:4078-4085.
29. Scarlatti G, Hodara V, Rossi P, Muggiasca L, Bucceri A, Albert J, Fenyo EM. 1993a. Transmission of human immunodeficiency virus type 1 (HIV-1) from mother to child correlates with viral phenotype. Virology 197:624-629.
30. Scarlatti G, Leitner T, Halapi E, Wahlberg J, Marchisio P, Clerici-Schoeller MA, Wigzell H, Fenyo EM, Albert J, Uhlen M. 1993b. Comparison of variable region 3 sequences of human immunodeficiency virus type 1 from infected children with the RNA and DNA sequences of the virus populations of their mothers. Proc Natl Acad Sci USA 90:1721-1725.
31. Shioda T, Levy JA, Cheng-Mayer C. 1992. Small amino acid changes in the V3 hypervariable region of gp120 can affect the T-cell line and macrophage tropisms of human immunodeficiency virus type 1. Proc Natl Acad Sci USA 89:9434-9438.
32. Simmons G, Wilkinson D, Reeves JD, Dittmar MT, Beddows S, Weber J, Carnegie G, Desselberger U, Gray PW, Weiss RA, Clapham PR. 1996. Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as co-receptors for virus entry. J Virol 70:8355-8360.
33. Simmons G, Reeves JD, McKnight A, Dejucq N, Hibbitts S, Power CA, Aarons E, Schols D, De Clercq E, Proudfoot AEI, Clapham PR. 1998. CXCR4 as a functional co-receptor for human immunodeficiency virus type 1 infection of primary macrophages. J Virol 72: 8453-8457.
34. Smith SD, Shatsky M, Cohen PS, Warnke R, Link MP, Glader BE. 1984. Monoclonal antibody and enzymatic profiles of human malignant T-lymphoid cells and derived cell lines. Cancer Res 44: 5657-5660.
35. Spencer LT, Ogino MT, Dankner WM, Spector SA. 1994. Clinical significance of human immunodeficiency virus type 1 phenotype in infected children. J Infect Dis 169:491-495.
36. Tersmette M, de Goede REY, Al BJM, Winkel IN, Gruters RA, Cuypers HT, Huisman HG, Miedema F. 1988. Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. J Virol 62:2026-2032.
37. Tersmette M, Gruters RA, de Wolf F, de Goede REY, Lange JMA, Schellekens PTA, Goudsmit J, Huisman HG, Miedema F. 1989. Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates. J Virol 63:2118-2125.
38. Tuttle DL, Harrison JK, Anders CB, Sleasman JW, Goodenow MM. 1998. Expression of CCR5 increases during monocyte differentiation and mediates macrophage susceptibility to infection by human immunodeficiency virus type 1. J Virol 72:4962-4969.
39. Zhang L, Huang Y, He T, Cao Y, Ho DD. 1996. HIV-1 subtype and second-receptor use. Nature 383:768.