The effects of ropivacaine on sodium currents in dorsal horn neurons of neonatal rats

Anesthesia and Analgesia

Volumn 90, Issue 5, 2000, Pages 1034-1038

  Liu, Bao Gang ^a   Zhuang, Xin Liang ^a   Li, Shi Tong ^a   Xu, Guo Hui ^a  

^a SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; LOCAL ANESTHETIC AGENT; ROPIVACAINE;

ANESTHESIA MECHANISM; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ION CURRENT; LOCAL ANESTHESIA; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM CURRENT; SPINAL CORD DORSAL HORN;

EID: 0034015859     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200005000-00007     Document Type: Article

References (14)

1. Griffin RP, Reynolds F. Extradural anaesthesia for caesarean section: a double-blind comparison of 0.5% ropivacaine with 0.5% bupivacaine. Br J Anaesth 1995;74:512-6.
2. Markham A, Faulds D. Ropivacaine: a review of its pharmacology and therapeutic use in regional anaesthesia. Drugs 1996;52: 429-49.
3. Wildsmith JA, Brown DT, Paul D, Johnson S. Structure-activity relationships in differential nerve block at high and low frequency stimulation. Br J Anaesth 1989;63:444-52.
4. Butterworth JF, Strichartz GR. Molecular mechanism of local anesthesia: a review. Anesthesiology 1990;72:711.
5. Murase K, Randic M. Electrophysiological properties of rat spinal dorsal horn neurons in vitro-calcium-dependent action potentials. J Physiol 1983;334:141-53.
6. Murase K, Randic M. Actions of substance P on rat spinal dorsal horn neurons. J Physiol 1984;346:203-17.
7. Murase K, Ryu PD, Randic M. Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons. Neurosci Lett 1989;103:56-63.
8. Safronov BV, Wolff M, Vogel W. Functional distribution of three types of sodium channel on soma and processes of dorsal horn neurons of rat spinal cord. J Physiol 1997;503:371-85.
9. Heath MJS, Womack, MacDekmott AB. Substance P elevates intracellular calcium in both neurons and glial cells from the dorsal horn of the spinal cord. J Neurophysiol 1994; 72:1192-8.
10. Hille B. The common mode of action of three agents that decrease the transient change in sodium permeability in nerves. Nature 1966;210:1220-3.
11. + currents by local anesthetics in the dorsal horn neurons of the spinal cord. Anesthesiology 1998;88:172-9.
12. Guo X, Castle NA, Chernoff DM, Strichartz GR. Comparative inhibition of voltage-gated cation channels by local anesthetic. Ann N Y Acad Sci 1991;625:181-99.
13. Owen MD, D'Angelok, Gerancher JC, et al. 0.125% ropivacaine is similar to 0.125% bupivacaine for labor analgesia using patient-controlled epidural infusion. Anesth Anag 1998;86: 527-31.
14. Crosby E, Sandler A, Finucane B, et al. Comparison of epidural anaesthesia with ropivacaine 0.5% and bupivacaine 0.5% for caesarean section. Can J Anaesth 1998;45:1066-71.