A novel lipid mediator, cyclic phosphatidic acid (cPA), and its biological functions

Annals of the New York Academy of Sciences

Volumn 905, Issue , 2000, Pages 319-321

  Murakami Murofushi, Kimiko ^a   Mukai, Mutsuko ^b   Kobayashi, Susumu ^c   Kobayashi, Tetsuyuki ^a   Tigyi, Gabor ^d   Murofushi, Hiromu ^e  

^a OCHANOMIZU UNIVERSITY   (Japan)

^b OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC PHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID; UNCLASSIFIED DRUG;

CALCIUM TRANSPORT; CONFERENCE PAPER; HUMAN; HUMAN CELL; METASTASIS INHIBITION; MITOSIS INHIBITION; PHYSARUM; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

PHYSARUM;

EID: 0034015653     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06570.x     Document Type: Conference Paper

References (5)

1. 1. MURAKAMI-MUROFUSHI, K., et al. 1992. Inhibition of eukaryotic DNA polymerase α with a novel lysophosphatidic acid (PHYLPA) isolated from myxoamoebae of Physarum polycephalum. J. Biol. Chem. 267: 21512-21517.
2. 2. MURAKAMI-MUROFUSHI, K., et al. 1993. Inhibition of cell proliferation by a unique lysophosphatidic acid, PHYLPA, isolated from Physarum polycephalum: signaling events of antiproliferative action by PHYLPA. Cell Struct. Funct. 18: 363-370.
3. 3. FISCHER, D., et al. 1998. Naturally occurring analogs of lysophosphatidic acid elicit different cellular responses through selective activation of multiple receptor sub-types. Mol. Pharmacol. 54: 979-988.
4. 4. MUKAI, M., et al. 1999. Inhibition of tumor invasion and metastasis by a novel lysophosphatidic acid (cyclic LPA). Int. J. Cancer 81: 918-922.
5. 5. KOBAYASHI, S., et al. 1993. Synthesis of 1-O-acylglycerol 2,3-cyclic phosphate: determination of the absolute structure of PHYLPA, a specific inhibitor of DNA polymerase α. Tetrahedron Lett. 34: 4047-4050.