FMRFamides exert a unique modulation of rodent pancreatic polypeptide sensitive neuropeptide Y (NPY) receptors

Canadian Journal of Physiology and Pharmacology

Volumn 78, Issue 2, 2000, Pages 150-161

  Parker, Steven L ^a   Parker, Michael S ^b  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MEMPHIS   (United States)

Author keywords

Allosteric interaction; Amino acid chirality; Hydrophobic pocket; RFamide; Y1 receptor; Y2 receptor; Y5 receptor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; AMILORIDE; CHLOROETHYLCLONIDINE; LIGAND; NEUROPEPTIDE Y RECEPTOR; PANCREAS POLYPEPTIDE; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE; PHOSPHOLIPASE C INHIBITOR;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL TYPE; CHIRALITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; STEADY STATE;

EID: 0034015568     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y99-126     Document Type: Article

References (46)

1. 2 receptors with distinguished conformations. Eur. J. Biochem. 225: 947-958.
2. 1 conforms to other mammalian receptors. Peptides, 20: 1043-1053.
3. Bischoff, A., Avramidis, P., Erdbrugger, W., Munter, K., and Michel, M.C. 1997. Receptor subtypes Y1 and Y5 are involved in the renal effects of neuropeptide Y. Br. J. Pharmacol. 120: 1335-1343.
4. Clackson, T., and Wells, J.A. 1995. A hot spot of binding energy in a hormone-receptor interface. Science (Washington, D.C.), 267: 383-386.
5. Coscoy, S., Lingueglia, E., Lazdunski, M., and Barbry, P. 1998. The Phe-Met-Arg-Phe-amide-activated sodium channel is a tetramer. J. Biol. Chem. 273: 8317-8322.
6. Cottrell, G.A. 1997. The first peptide-gated ion channel. J. Exp. Biol. 200: 2377-2386.
7. Curry, W.J., Shaw, C., Johnston, C.F., Thim, L., and Buchanan, K.D. 1992. Neuropeptide F: primary structure from the turbellarian, Artioposthia triangulata. Comp. Biochem. Physiol. C, 101: 269-274.
8. Daniels, A.J., Matthews, J.E., Viveros, O.H., Leban, J.J., Cory, M., and Heyer, D. 1995. Structure-activity relationship of novel pentapeptide neuropeptide Y receptor antagonists is consistent with a noncontinuous epitope for ligand-receptor binding. Mol. Pharmacol. 48: 425-432.
9. Dougherty, D.A. 1996. Cation-π interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. Science (Washington, D.C.), 271: 163-168.
10. Du, P., Salon, J.A., Tamm, J.A., Cuifen, H., Cui, W., Walker, M.W., Adham, N., Dhanoa, D.S., Islam, I., Vaysse, P.J., Dowling, B., Shifman, Y., Boyle, N., Rueger, H., Schmidlin, T., Yamaguchi, Y., Branchek, T.A., Weinshank, R., and Gluchowski, C. 1997. Modeling the G-protein coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites. Protein Engineering, 10: 109-117.
11. 5 receptor subtype in the rat brain. J. Neurosci. 18: 5565-5574.
12. Eberlein, G.A., Eysselein, V.E., Davis, M.T., Lee, T.D., Shively, J.E., Grandt, D., Niebel, W., Williams, R., Moessner, J., and Zeeh, J. 1992. Patterns of prohormone processing. Order revealed by a new procholecystokinin-derived peptide. J. Biol. Chem. 267: 1517-1521.
13. 2 receptors. J. Biol. Chem. 265: 11 706-11 712.
14. Ganeshan, K., Perlman, M.O., Perlman, J.M., Adamo, M.L., Hazelwood, R.L., and Dyckes, D.F. 1987. Recognition of neuropeptides FMRFamide and LPLRFamide by chicken cerebellum avian pancreatic polypeptide binding sites. Proc. Soc. Exp. Biol. Med. 185: 409-412.
15. Garcia-Anoveros, J., Derfler, B., Neville-Golden, J., Hyman, B.T., and Corey, D.P. 1997. BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. Proc. Natl. Acad. Sci. U.S.A. 94: 1459-1464.
16. Gerald, C., Walker, M.W., Criscione, L., Gustafson, E.L., Batzl-Hartmann, C., Smith, K.E., Vaysse, P., Durkin, M.M., Laz, T.M., Linemeyer, D.L., Schaffhauser, A.O., Whitebread, S., Hofbauer, K.G., Taber, R.I., Branchek, T.A., and Weinshank, R.L. 1996. A receptor subtype involved in neuropeptide-Y-induced food intake. Nature (London), 382: 168-171.
17. 2-receptor by substituted and truncated neuropeptide-Y analogs. Identification of signal epitopes. Eur. J. Pharmacol. 232: 271-278.
18. Han, C., Abel, P.W., and Minneman, K.P. 1987. Heterogeneity of alpha 1-adrenergic receptors revealed by chlorethylclonidine. Mol. Pharmacol. 32: 505-510.
19. 2-adrenergic receptors by sodium. J. Biol. Chem. 265: 21 590-21 595.
20. Johansen, T.E., Scholler, M.S., Tolstoy, S., and Schwartz, T.W. 1990. Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors. FEBS Lett. 267: 289-294.
21. Kalra, S.P., and Crowley, W.R. 1992. Neuropeptide-Y: a novel neuroendocrine peptide in the control of pituitary hormone secretion, and its relation to luteinizing hormone. Frontiers Neuroendocrinol. 13: 1-46.
22. 2 affinities of the complete series of analogues with single D-residue substitutions. J. Med. Chem. 36: 3802-3808.
23. 2 on the molluscan smooth muscle. Gen. Pharmacol. 22: 959-964.
24. Kretsinger, R.H. 1987. Calcium coordination and the calmodulin fold: divergent versus convergent evolution. Cold Spring Harbor Symp. Quant. Biol. 52: 499-510.
25. Larhammar, D. 1996. Evolution of neuropeptide Y, peptide YY and pancreatic polypeptide. Regul. Pept. 62: 1-11.
26. Lingueglia, E., Champigny, G., Lazdunski, M., and Barbry, P. 1995. Cloning of the amiloride-sensitive FMRFamide peptidegated sodium channel. Nature (London), 378: 730-733.
27. + channel. Exp. Physiol. 81: 483-492.
28. Medeiros, M.D., and Turner, A.J. 1994. Processing and metabolism of peptide YY. Pivotal roles of dipeptidylpeptidase-IV, aminopeptidase-P, and endopeptidase-24.11. Endocrinology, 134: 2088-2094.
29. Mercier, A.J., Orchard, I., TeBrugge, V., and Skerrett, M. 1993. Isolation of two FMRFamide-related peptides from crayfish pericardial organs. Peptides, 14: 137-143.
30. Minneman, K.P., Han, C., and Abel, P.W. 1988. Comparison of alpha 1-adrenergic receptor subtypes distinguished by chlorethylclonidine and WB 4101. Mol. Pharmacol. 33: 509-514.
31. Munson, P.J., and Rodbard, D. 1980. LIGAND: a versatile computerized approach for characterization of ligand-binding proteins. Anal. Biochem. 107: 220-239.
32. 2 subtype of neuropeptide Y receptor of rat brain. Eur. J. Pharmacol. 318: 193-200.
33. 1 neuropeptide Y receptor in rat brain. Sensitivity to G-protein activators and inhibitors and to inhibitors of phospholipase C. J. Pharmacol. Exp. Ther. 286: 1-12.
34. 5 subtypes of neuropeptide Y (NPY) receptor in rabbit kidney. Regul. Pept. 75/76: 127-143.
35. 1 receptors in sensitivity to chaotropic agents, FMRF-amide analogues and amiloride derivatives. Society for Neuroscience 1998 Annual Meeting, Los Angeles, Calif. Abstr. 626.7.
36. 2 receptors in sensitivity to amiloride derivatives affecting sodium transport. Regul. Pept. 82: 91-102.
37. Parker, S.L., Parker, M.S., and Crowley, W.R. 1999b. FMRFamides exert a unique modulation of rodent pancreatic polypeptide-sensitive neuropeptide Y (NPY) receptors. Society for Neuroscience 1999 Annual Meeting, Miami Beach, Fla. Abstr. 225.1.
38. Payza, K., Akar, C.A., and Yang, H.Y. 1993. Neuropeptide FF receptors: structure-activity relationship and effect of morphine. J. Pharmacol. Exp. Ther. 267: 88-94.
39. 5 receptor. Eur. J. Pharmacol. 333: R3-R5.
40. Playford, R.J., and Cox, H.M. 1996. Peptide YY and neuropeptide Y: two peptides intimately involved in electrolyte homeostasis. Trends Pharmacol. Sci. 17: 436-438.
41. Price, J.S., Kenny, A.J., Huskisson, N.S., and Brown, M.J. 1991. Neuropeptide Y (NPY) metabolism by endopeptidase-2 hinders characterization of NPY receptors in rat kidney. Br. J. Pharmacol. 104: 321-326.
42. 1 muscarinic acetylcholine receptor gene. J. Biol. Chem. 263: 18 397 - 18 403.
43. 1-receptor mediating this peptide's effect. Peptides, 13: 581-587.
44. Wahlestedt, C., and Reis, D.J. 1993. Neuropeptide Y-related peptides and their receptors - are the receptors potential therapeutic drug targets? Annu. Rev. Pharmacol. Toxicol. 32: 309-352.
45. 1 neuropeptide Y receptor are essential for ligand binding. J. Biol. Chem. 269: 2863-2869.
46. Wells, J.A. 1996. Binding in the growth hormone receptor complex. Proc. Natl. Acad. Sci. U.S.A. 93: 1-6.