Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: Activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors

FASEB Journal

Volumn 14, Issue 7, 2000, Pages 973-981

  Foehr, Erik D ^a   Tatavos, Anie ^a   Tanabe, Eri ^a,c   Raffioni, Simona ^a   Goetz, Silke ^a,d   Dimarco, Eddi ^b   De Luca, Michele ^b,e   Bradshaw, Ralph A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d IDI Ist Dermopat dell'Immacol ^*  (Germany)

^e LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

Author keywords

Collagen receptor; Signal transduction; Tyrosine kinase

Indexed keywords

DISCOIDIN DOMAIN RECEPTOR 1; PHOSPHOLIPASE C; PLATELET DERIVED GROWTH FACTOR RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0034015551     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.14.7.973     Document Type: Article

References (33)

1. Schlessinger, J., and Ullrich, A. (1992) Growth factor signaling by receptor tyrosine kinases. Neuron 9, 383-391
2. Pawson, T., and Scott, J. D. (1997) Signaling through scaffold, anchoring, and adaptor proteins. Science 278, 2075-0280
3. Heldin, C. H., and Purton, M. (1996) Signal Transduction, Chapman and Hall, London
4. Plowman, G. D., Sudarsanam, S., Bingham, J., Whyte, D., and Hunter, T. (1999) The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms. Proc. Natl. Acad. Sci. USA 96, 13603-13610
5. Shrivastava, A., Radziejewski, G., Campbell, E., Kovac, L., McGlynn, M., Ryan, T. E., Davis, S., Goldfarh, M. P., Glass, D. J., Lemke, G., and Yancopoulos, G. D. (1997) An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors. Mol. Cell 1, 25-34
6. Vogel, W., Gish, G. D., Alves, F., and Pawson, T. (1997) The discoidin domain receptor tyrosine kinases are activated by collagen. Mol. Cell 1, 13-23
7. Schlessinger, J. (1997) Direct binding and activation of receptor tyrosine kinases by collagen. Cell 91, 869-872
8. Alves, F., Vogel, W., Mossie, K., Millauer, B., Höfler, H., and Ullrich, A. (1995) Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer. Oncogene 10, 609-618
9. Di Marco, E., Cutuli, N., Guerra, L., Cancedda, R., and De Luca, M. (1993) Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues. J. Biol. Chem. 268, 24290-24295
10. Laval, S., Butler, R., Shelling, A. N., Hanby, A. M., Poulsom, R., and Ganesan, T. S. (1994) Isolation and characterization of an epithelial-specific receptor tyrosine kinase from an ovarian cancer cell line. Cell Growth Differ. 5, 1173-1183
11. Perez, J. L., Jing, S. Q., and Wong, T. W. (1996) Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines. Oncogene 12, 1469-1477
12. Sanchez, M. P., Tapley, P., Saini, S. S., He, B., Pulido, D., and Barbacid, M. (1994) Multiple tyrosine protein kinases in rat hippocampal neurons: isolation of Ptk-3, a receptor expressed in proliferative zones of the developing brain. Proc. Natl. Acad. Sci. USA 91, 1819-1823
13. Zerlin, M., Julius, M. A., and Goldfarb, M. (1993) NEP: a novel receptor-like tyrosine kinase expressed in proliferating neuroepithelia. Oncogene 8, 2731-2739
14. Karn, T., Holtrich, U., Bräuninger, A., Böhme, B., Wolf, G., Rübsamen-Waigmann, H., and Strebhardt, K. (1993) Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain. Oncogene 8, 3433-3440
15. Lai, C., and Lemke, G. (1991) An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron 6, 691-704
16. Johnson, J. D., Edman, J. C., and Rutter, W. J. (1993) A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain [published erratum appears in Proc. Natl. Acad. Sci. USA (1993) Vol. 90, p. 10891]. Proc. Natl. Acad. Sci. USA 90, 5677-5681
17. Di Marco, E., Mathor, M., Bondanza, S., Cutuli, N., Marchisio, P. C., Cancedda, R., and De Luca, M. (1993) Nerve growth factor binds to normal human keratinocytes through high and low affinity receptors and stimulates their growth by a novel autocrine loop. J. Biol. Chem. 268, 22838-22846
18. Springer, W. R., Cooper, D. N., and Barondes, S. H. (1984) Discoidin I is implicated in cell-substratum attachment and ordered cell migration of Dictyostelium discoideum and resembles fibronectin. Cell 39, 557-564
19. Obermeier, A., Bradshaw, R. A., Seedorf, K., Choidas, A., Schlessinger, J., and Ullrich, A. (1994) Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma. EMBO J. 13, 1585-1590
20. Foehr, E. D., Raffioni, S., Fuji, R., and Bradshaw, R. A. (1998) FGF signal transduction in PC12 cells: comparison of the responses induced by endogenous and chimeric receptors. Immunol. Cell Biol. 76, 406-413
21. Obermeier, A., Halfter, H., Wiesmüller, K. H., Jung, G., Schlessinger, J., and Ullrich, A. (1993) Tyrosine 785 is a major determinant of Trk-substrate interaction. EMBO J. 12, 933-941
22. Chen, C., and Okayama, H. (1987) High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752
23. Vambutas, V., Kaplan, D. R., Sells, M. A., and Chernoff, J. (1995) Nerve growth factor stimulates tyrosine phosphorylation and activation of Src homology-containing protein-tyrosine phosphatase 1 in PC12 cells. J. Biol. Chem. 270, 25629-25633
24. Raffioni, S., Thomas, D., Foehr, E. D., Thompson, L. M., and Bradshaw, R. A. (1999) Comparison of the intracellular signaling responses by three chimeric fibroblast growth factor receptors in PC12 ceils. Proc. Natl. Acad. Sci. USA 96, 7178-7183
25. Marais, R., Light, L., Mason, C., Paterson, H., Olson, M. F., and Marshall, C. J. (1998) Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C [published erratum appears in Science (1998) Vol. 280, p. 987]. Science 280, 109-112
26. Heldin, C. H. (1995) Dimerization of cell surface receptors in signal transduction. Cell 80, 213-223
27. Hubbard, S. R., Mohaminadi, M., and Schlessinger, J. (1998) Autoregulatory mechanisms in protein-tyrosine kinases. J. Biol. Chem. 273, 11987-11990
28. Raffioni, S., Zhu, Y. Z., Bradshaw, R. A., and Thompson, L. M. (1998) Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation. J. Biol. Chem. 273, 35250-35259
29. Xu, H., Lee, K. W., and Goldfarb, M. (1998) Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins. J. Biol. Chem. 273, 17987-17990
30. Yoon, S. O., Soltoff, S. P., and Chao, M. V. (1997) A dominant role of the juxtamembrane region of the TrkA nerve growth factor receptor during neuronal cell differentiation. J. Biol. Chem. 272, 23231-23238
31. van der Geer, P., Wiley, S., Gish, G. D., and Pawson, T. (1996) The She adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions. Curr. Biol. 6, 1435-1444
32. Harmer, S. L., and DeFranco, A. L. (1997) She contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes. Mol. Cell. Biol. 17, 4087-4095
33. Thomas, D., and Bradshaw, R. A. (1997) Differential utilization of ShcA tyrosine residues and functional domains in the transduction of epidermal growth factor-induced mitogen-activated protein kinase activation in 293T cells and nerve growth factor-induced neunte outgrowth in PC12 cells. Identification of a new Grb2.Sos1 binding site. J. Biol. Chem. 272, 22293-22299