Modulation of cross-bridge interaction by 2,3-butanedione monoxime in human ventricular myocardium

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 361, Issue 4, 2000, Pages 440-444

  Brixius, Klara ^a   Schwinger, Robert H G ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Cardioplegia; Contractile apparatus; Contractile function; Heart failure

Indexed keywords

CALCIUM ION; DIACETYL OXIME; MYOSIN ADENOSINE TRIPHOSPHATASE;

ADULT; ARTICLE; CARDIOMYOPATHY; CARDIOPLEGIA; CONTROLLED STUDY; FEMALE; HEART FAILURE; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HEART PROTECTION; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; MALE;

ADULT; CALCIUM; CARDIOMYOPATHY, DILATED; CARDIOPLEGIC SOLUTIONS; DIACETYL; FEMALE; HEART; HEART VENTRICLES; HUMANS; MALE; MIDDLE AGED; MUSCLE FIBERS; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOSINS;

EID: 0034014768     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002109900209     Document Type: Article

References (21)

1. i and cross-bridge kinetics. J Physiol (Lond) 476:487-500
2. 2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: Implications for regulation of muscle contraction. Proc Natl Acad Sci USA 85:3265-3269
3. Brotto MA, Fogacaa RT, Crezzo TL, Godt RE, Nosek TM (1995) The effect of 2,3-butanedione 2-monoximne (BDM) on ventricular trabeculae from the avian heart. J Muscle Res Cell Motil 6:1-10
4. Ebus JP, Stienen GJM (1996) Effects of 2,3-butanedione monoxime on cross-bridge kinetics in rat cardiac muscle. Pflugers Arch 432:921-929
5. Fabiato A, Fabiato F (1979) Calculator programs for computing the compositions of the solutions containing metals and ligands used for experiments in skinned muscle cells. J Physiol Paris 75:463-505
6. Güth K, Wojciechowski R (1986) Perfusion cuvette for the simultaneous measurement of mechanical, optical, and energetic parameters of skinned muscle fibers. Pflugers Arch 407:552-557
7. Gwathmey JK, Hajjar RJ, Solaro RJ (1991) Contractile deactivation and uncoupling of crossbridges. Circ Res 69:1280-1292
8. Herrmann C, Wray J, Travers F, Barnman T (1992) Effect of 2,3-butanedione monoxime on myosin and myofibrillar ATPases. An example of an uncompetitive inhibitor. Biochem J 31:12227-12232
9. HigucHi H, Takemori S (1989) Butanedione monoxime suppresses contraction and ATPase activity of rabbit skeletal muscle. J Biochem 105:638-643
10. Horiuti K, Higuchi H, Umazume Y, Konishi M, Okazaki O, Kurihara S (1988) Mechanisms of action of 2,3-butanedione 2-monoxime on contraction of frog skeletal muscle fibers. J Muscle Res Cell Motil 9:156-164
11. Huxley AF (1957) Muscle structure and theories of contraction. Prog Biophys Chem 7:55-318
12. Lammerich A, Holzhutter HG, Janiak R, Storch E, Gunther J (1994) Interpretation of the inotropic effect of 2,3-butanedione monoxime on the isometric twitch of guinea-pig papillary muscle. Gen Physiol Biophys 13:377-392
13. Li T, Sperelakis N, Teneick RE, Solaro RJ (1985) Effects of diacetyl monoxime on cardiac excitation-contraction coupling. J Pharmacol Exp Ther 232:688-695
14. Loxdale Hd (1976) A method for the continuous assay of picomole quantities of ADP released from glycerol-extracted skeletal muscle fibers on MgATP activation. J Physiol (Lond) 260: 4P-5P
15. Mulieri LA, Hasenfuss G, Ittleman F, Edward MB, Alpert NR (1989) Protection of human left ventricular myocardium from cutting injury with 2,3-butanedione monoxime. Circ Res 65: 1441-1444
16. Packer CS, Kagan ML, Kagan JF, Robertson SA, Stephens Nl (1988) The effect of 2,3-butanedione monoxime (BDM) in smooth muscle mechanical properties. Pflugers Arch 412:659-664
17. Schwinger RHG, BöhM M, Koch A, Erdmann E (1992) Beneficial cardioprotective actions of BDM on human myocardium. Eur Heart J [Suppl] 13:1-27
18. Schwinger RHG, Böhm M, Koch A, Morano I, Rüegg JC, Erdmann E (1994a) Inotropic effect of the cardioprotective agent 2,3-butanedione monoxime in failing and nonfailing human myocardium. J Pharmacol Exp Ther 269:778-786
19. Schwinger RHG, BöhM M, Koch A, Schmidt U, Morano I, Eissner H-J, Überfuhr P, Reichart B, Erdmann E (1994b) The failing human myocardium is unable to use the Frank-Starling mechanism. Circ Res 74:959-969
20. Stringham JC, Paulsen KL, Southard JH, Mentzer RM, Belzer FO (1994) Prolonging myocardial preservation with a modified University of Wisconsin solution containing 2,3-butanedione monoxime and calcium. J Thorac Cardiovasc Surg 107:764-775
21. Zhao Y, Kawai M (1994) BDM affects nucleotide binding and force generation steps of the cross-bridge cycle in rabbit psoas muscle fiber. Am J Physiol 266:C437-C447