메뉴 건너뛰기




Volumn 43, Issue 3, 2000, Pages 233-242

Analysis of cyclin-dependent kinase inhibitor expression and methylation patterns in human prostate cancers

Author keywords

Cyclin dependent kinase inhibitor; DNA methylation; p16; RB

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; MESSENGER RNA; MONOCLONAL ANTIBODY; PROTEIN P15; PROTEIN P16;

EID: 0034013724     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(20000515)43:3<233::AID-PROS10>3.0.CO;2-S     Document Type: Article
Times cited : (57)

References (61)
  • 1
    • 0029687491 scopus 로고    scopus 로고
    • Genetic regulation of androgen action
    • Kallio PJ, Palvimo JJ, Janne OA. Genetic regulation of androgen action. Prostate [Suppl] 1996;6:45-51.
    • (1996) Prostate , vol.6 , Issue.SUPPL. , pp. 45-51
    • Kallio, P.J.1    Palvimo, J.J.2    Janne, O.A.3
  • 2
    • 0029065994 scopus 로고
    • Endocrine control of prostate cancer
    • Wilding G. Endocrine control of prostate cancer. Cancer Surv 1995;23:43-62.
    • (1995) Cancer Surv , vol.23 , pp. 43-62
    • Wilding, G.1
  • 6
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/ CDKN2/MTS1 in human cancers. Nat Med 1995;1:686-692.
    • (1995) Nat Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 7
    • 0028875205 scopus 로고
    • Methylation of the 5′CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M, Bender CM, Yang AS, Nguyen TD, Beart RW, Van Tornout JM, Jones PA. Methylation of the 5′CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res 1995;55:4531-4535.
    • (1995) Cancer Res , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Nguyen, T.D.4    Beart, R.W.5    Van Tornout, J.M.6    Jones, P.A.7
  • 9
    • 0029665954 scopus 로고    scopus 로고
    • p16ink4a gene and hematological malignancies
    • Quesnel B, Preudhomme C, Fenaux P. p16ink4a gene and hematological malignancies. Leuk Lymphoma 1996;22:11-24.
    • (1996) Leuk Lymphoma , vol.22 , pp. 11-24
    • Quesnel, B.1    Preudhomme, C.2    Fenaux, P.3
  • 10
    • 0029134016 scopus 로고
    • Role of the cyclin-dependent kinase inhibitors in the development of cancer
    • Hirama T, Koeffler HP. Role of the cyclin-dependent kinase inhibitors in the development of cancer. Blood 1995;86:841-854.
    • (1995) Blood , vol.86 , pp. 841-854
    • Hirama, T.1    Koeffler, H.P.2
  • 11
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, Sidransky D, Baylin SB. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995;55:4525-4530.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 13
    • 0029121213 scopus 로고
    • Mutational analysis of CDKN2 (CDK4I/MTS1) gene in tissues and cell lines of human prostate cancer
    • Komiya A, Suzuki H, Aida S, Yatani R, Shimazaki J. Mutational analysis of CDKN2 (CDK4I/MTS1) gene in tissues and cell lines of human prostate cancer. Jpn J Cancer Res 1995;86:622-625.
    • (1995) Jpn J Cancer Res , vol.86 , pp. 622-625
    • Komiya, A.1    Suzuki, H.2    Aida, S.3    Yatani, R.4    Shimazaki, J.5
  • 17
    • 0031978025 scopus 로고    scopus 로고
    • Analysis of the p16 tumor suppressor gene in early-stage prostate cancer
    • Gu K, Mes-Masson A-M, Gauthier J, Saad F. Analysis of the p16 tumor suppressor gene in early-stage prostate cancer. Mol Carcinog 1998;21:164-170.
    • (1998) Mol Carcinog , vol.21 , pp. 164-170
    • Gu, K.1    Mes-Masson, A.-M.2    Gauthier, J.3    Saad, F.4
  • 18
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle DE, Zindy F, Ashmun RA, Sherr CJ. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 1995;83: 993-1000.
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 19
    • 0028168242 scopus 로고
    • INK4B is a potential effector of TGF-beta-induced cell cycle arrest
    • INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature 1994;371:257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 20
    • 0030778842 scopus 로고    scopus 로고
    • Splicing into senescence: The curious case of p16 and p19ARF
    • Haber DA. Splicing into senescence: the curious case of p16 and p19ARF. Cell 1997;91555-558.
    • (1997) Cell , vol.91 , pp. 555-558
    • Haber, D.A.1
  • 22
    • 0027749203 scopus 로고
    • Hormonal regulation of transforming growth factor beta-2 expression in human prostate cancer
    • Knabbe C, Klein H, Zugmaier G, Voigt KD. Hormonal regulation of transforming growth factor beta-2 expression in human prostate cancer. J Steroid Biochem Mol Biol 1993;47:137-142.
    • (1993) J Steroid Biochem Mol Biol , vol.47 , pp. 137-142
    • Knabbe, C.1    Klein, H.2    Zugmaier, G.3    Voigt, K.D.4
  • 23
    • 0030787152 scopus 로고    scopus 로고
    • Mechanism and function of signaling by the TGF beta superfamily
    • Hoodless PA, Wrana JL. Mechanism and function of signaling by the TGF beta superfamily. Curr Top Microbiol Immunol 1998;228:235-272.
    • (1998) Curr Top Microbiol Immunol , vol.228 , pp. 235-272
    • Hoodless, P.A.1    Wrana, J.L.2
  • 24
    • 0031019319 scopus 로고    scopus 로고
    • Transforming growth factor beta as a clinical biomarker for prostate cancer
    • Perry KT, Anthony CT, Case T, Steiner MS. Transforming growth factor beta as a clinical biomarker for prostate cancer. Urology 1997;49:151-155.
    • (1997) Urology , vol.49 , pp. 151-155
    • Perry, K.T.1    Anthony, C.T.2    Case, T.3    Steiner, M.S.4
  • 25
    • 0026600577 scopus 로고
    • Transforming growth factor-beta 1 over-production in prostate cancer: Effects on growth in vivo and in vitro
    • Steiner MS, Barrack ER. Transforming growth factor-beta 1 over-production in prostate cancer: effects on growth in vivo and in vitro. Mol Endocrinol 1992;6:15-25.
    • (1992) Mol Endocrinol , vol.6 , pp. 15-25
    • Steiner, M.S.1    Barrack, E.R.2
  • 27
    • 0027984473 scopus 로고
    • Expression of transforming growth factor-beta1 in prostate cancer
    • Steiner M, Zhou Z-Z, Tonb DC, Barrack ER. Expression of transforming growth factor-beta1 in prostate cancer. Endrocinology 1994;135:2240-2247.
    • (1994) Endrocinology , vol.135 , pp. 2240-2247
    • Steiner, M.1    Zhou, Z.-Z.2    Tonb, D.C.3    Barrack, E.R.4
  • 28
    • 0029805136 scopus 로고    scopus 로고
    • Incidence of apoptosis and cell proliferation in prostate cancer: Relationship with TGF-beta1 and bcl-2 expression
    • Tu H, Jacobs SC, Borkowski A, Kyprianou N. Incidence of apoptosis and cell proliferation in prostate cancer: relationship with TGF-beta1 and bcl-2 expression. Int J Cancer 1996;69:357-363.
    • (1996) Int J Cancer , vol.69 , pp. 357-363
    • Tu, H.1    Jacobs, S.C.2    Borkowski, A.3    Kyprianou, N.4
  • 30
    • 85047680777 scopus 로고    scopus 로고
    • Antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation
    • Zhuang SH, Burnstein K. Antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation. Endocrinology 1998;139:1197-1207.
    • (1998) Endocrinology , vol.139 , pp. 1197-1207
    • Zhuang, S.H.1    Burnstein, K.2
  • 31
    • 0030065422 scopus 로고    scopus 로고
    • Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
    • Liu M, Lee MH, Cohen M, Bommakanti M, Freedman LP. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev 1996;10:142-153.
    • (1996) Genes Dev , vol.10 , pp. 142-153
    • Liu, M.1    Lee, M.H.2    Cohen, M.3    Bommakanti, M.4    Freedman, L.P.5
  • 33
    • 0030954428 scopus 로고    scopus 로고
    • CG island methylation changes near the GSTP1 gene in prostatic carcinoma cells detected using the polymerase chain reaction: A new prostate cancer biomarker
    • Lee WH, Isaacs WB, Bova GS, Nelson WG. CG island methylation changes near the GSTP1 gene in prostatic carcinoma cells detected using the polymerase chain reaction: a new prostate cancer biomarker. Cancer Epidemiol Biomarkers Prev 1997;6: 443-450.
    • (1997) Cancer Epidemiol Biomarkers Prev , vol.6 , pp. 443-450
    • Lee, W.H.1    Isaacs, W.B.2    Bova, G.S.3    Nelson, W.G.4
  • 36
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 38
    • 0030738231 scopus 로고    scopus 로고
    • Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)
    • Gonzalgo M, Jones PA. Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res 1997;25:2529-2531.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2529-2531
    • Gonzalgo, M.1    Jones, P.A.2
  • 40
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 1997;25:2532-2534.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 42
    • 0020414426 scopus 로고
    • Familial prostatic cancer risk and low testosterone
    • Meikle AW, Stanish WM. Familial prostatic cancer risk and low testosterone. J Clin Endocrinol Metab 1982;54:1104-1108.
    • (1982) J Clin Endocrinol Metab , vol.54 , pp. 1104-1108
    • Meikle, A.W.1    Stanish, W.M.2
  • 45
    • 0030046322 scopus 로고    scopus 로고
    • Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B
    • Herman JG, Jen J, Merlo A, Baylin SB. Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B. Cancer Res 1996;56:722-727.
    • (1996) Cancer Res , vol.56 , pp. 722-727
    • Herman, J.G.1    Jen, J.2    Merlo, A.3    Baylin, S.B.4
  • 46
    • 0030729040 scopus 로고    scopus 로고
    • Expression of p16 protein in prostatic adenocarcinomas, intraepithelial neoplasia, and benign/hyperplastic glands
    • Halvorsen OJ, Haukaas S, Hoisaeter PA, Akslen LA. Expression of p16 protein in prostatic adenocarcinomas, intraepithelial neoplasia, and benign/hyperplastic glands. Urol Oncol 1997;3:59-66.
    • (1997) Urol Oncol , vol.3 , pp. 59-66
    • Halvorsen, O.J.1    Haukaas, S.2    Hoisaeter, P.A.3    Akslen, L.A.4
  • 47
    • 0029023626 scopus 로고
    • Senescent human fibroblasts resist programmed cell death and failure to suppress bcl2 is involved
    • Wang E. Senescent human fibroblasts resist programmed cell death and failure to suppress bcl2 is involved. Cancer Res 1995; 55:2284-2292.
    • (1995) Cancer Res , vol.55 , pp. 2284-2292
    • Wang, E.1
  • 48
    • 0030887851 scopus 로고    scopus 로고
    • Aging and cancer: The double-edged sword of replicative senescence
    • Campisi J. Aging and cancer: the double-edged sword of replicative senescence. J Am Geriatr Soc 1997;45:482-488.
    • (1997) J Am Geriatr Soc , vol.45 , pp. 482-488
    • Campisi, J.1
  • 49
    • 0029670840 scopus 로고    scopus 로고
    • Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
    • Hara E, Smith R, Parry D, Tahara H, Stone S, Peters G. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol Cell Biol 1996;16:859-867.
    • (1996) Mol Cell Biol , vol.16 , pp. 859-867
    • Hara, E.1    Smith, R.2    Parry, D.3    Tahara, H.4    Stone, S.5    Peters, G.6
  • 50
    • 0032510327 scopus 로고    scopus 로고
    • Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
    • McConnell BB, Starborg M, Brookes S, Peters G. Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts. Curr Biol 1998;8:351-354.
    • (1998) Curr Biol , vol.8 , pp. 351-354
    • McConnell, B.B.1    Starborg, M.2    Brookes, S.3    Peters, G.4
  • 54
    • 0028869884 scopus 로고
    • Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product
    • Parry D, Bates S, Man DJ, Peters G. Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product. EMBO J 1995;14:503-511.
    • (1995) EMBO J , vol.14 , pp. 503-511
    • Parry, D.1    Bates, S.2    Man, D.J.3    Peters, G.4
  • 58
    • 0028836691 scopus 로고
    • Allelic loss of the retinoblastoma gene in primary human prostatic adenocarcinomas
    • Brooks JD, Bova S, Isaacs WB. Allelic loss of the retinoblastoma gene in primary human prostatic adenocarcinomas. Prostate 1995;26:35-39.
    • (1995) Prostate , vol.26 , pp. 35-39
    • Brooks, J.D.1    Bova, S.2    Isaacs, W.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.