The vascularized pig fibula bone flap model: Effect of segmental osteotomies and internal fixation on blood flow

Plastic and Reconstructive Surgery

Volumn 105, Issue 3, 2000, Pages 1004-1012

  Chiodo, Alan A ^b   Gur, Eyal ^b   Pang, Cho Y ^b   Neligan, Peter C ^b   Boyd, J Brian ^b   Binhammer, Paul M ^b   Forrest, Christopher R ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BONE BLOOD FLOW; BONE GRAFT; CONTROLLED STUDY; FIBULA; FREE TISSUE GRAFT; NONHUMAN; OSTEOSYNTHESIS; OSTEOTOMY; PRIORITY JOURNAL; SURGICAL TECHNIQUE; SWINE;

EID: 0034013572     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006534-200003000-00025     Document Type: Article

References (39)

1. Urken, M. I. Composite free flaps in oromandibular reconstruction. Arch. Otolaryngol. Head Neck Surg. 117: 724, 1991.
2. Urken, M. I., Weinberg, H., Vickery, C., Buchbinder, D., Lawson, W., and Biller, H. F. Oromandibular reconstruction using microvascular composite free flaps: Report of 71 cases and a new classification scheme for bony, soft-tissue, and neurologic defects. Arch. Otolaryngol. Head Neck Surg. 117: 733, 1991.
3. Hidalgo, D. A. Fibula free flap: A new method of mandible reconstruction. Plast. Reconstr. Surg. 84: 71, 1989.
4. Flemming, A. F., Brough, M. D., Evans, N. D., et al. Mandibular reconstruction using vascularized fibula. Br. J. Plast. Surg. 43: 403, 1990.
5. Wei, F. C., Seah, C. S., Tsai, Y. C., Liu, S. I., and Tsai, M. S. Fibula osteoseptocutaneous flap for reconstruction of composite mandibular defects. Plast. Reconstr. Surg. 93: 294, 1994.
6. Lyberg, T., and Olstad, O. A. The vascularized fibular flap for mandibular reconstruction. J. Craniomaxillofac. Surg. 19: 113, 1991.
7. Cheung, S. W., Anthony, J. P., and Singer, M. I. Restoration of anterior mandible with the free fibula osseocutaneous flap. Laryngoscope 104: 1305, 1994.
8. Hidalgo, D. A. Aesthetic improvements in free-flap mandible reconstruction. Plast. Reconstr. Surg. 88: 574, 1991.
9. Hidalgo, D. A. Titanium miniplate fixation in free-flap mandible construction. Ann. Plast. Surg. 23: 498, 1989.
10. Shpitzer, T., Neligan, P. C., Gullane, P., et al. Oromandibular reconstruction with the free fibula flap: Analysis of 50 consecutive flaps. Arch. Otolaryngol. Head Neck Surg. 123: 939, 1997.
11. Shpitzer, T., Neligan, P. C., Gullane, P., et al. The free iliac crest and fibula flaps in vascularized oromandibular reconstruction: Comparison and long-term evaluation. Arch. Otolaryngol. Head Neck Surg. 21: 639, 1999.
12. Shaffer, J. W., Davy, D. T., Field, G. A., and Benstisan, J. S. Temporal analysis of vascularized and nonvascularized rib grafts in canine spine surgery. Spine 14: 727, 1989.
13. Shaffer, J. W., Field, G. A., Goldberg, V.M., and Davy, D. T. Fate of vascularized and non-vascularized autografts. Clin. Orthop. 197: 32, 1985.
14. Puckett, C. L., Hurvitz, J. S., Metzler, M. H., and Silver, D. Bone formation by revascularized periosteal and bone grafts, compared with traditional bone grafts. Plast. Reconstr. Surg. 64: 361, 1979.
15. Berggren, A., Weiland, A. J., and Dorfman, H. Free vascularized bone grafts: Factors affecting their survival and ability to heal to recipient bone defects. Plast. Reconstr. Surg. 69: 19, 1982.
16. Zdeblick, T. A., Shafer, J. W., and Field, G. A. The healing of canine vascularized segmental tibial osteotomies: The effect of retained endosteal circulation. Clin. Orthop. Rel. Res. 236: 296, 1988.
17. Shaffer, J. W., Field, G. A., Goldberg, V. M., and Zdelblick, T. A. A vascularized fibula model to study vascularized canine bone grafts. Microsurgery 5: 185, 1984.
18. Ford-Jones, N., Swartz, W. M., Mears, D. C., Jupiter, J. B., and Grossman, A. The "double barrel" free vascularized fibular bone graft. Plast. Reconstr. Surg. 81: 378, 1988.
19. Chiodo, A. A., Forrest, C. R., Pang, C. Y., Neligan, P. C., and Boyd, J. B. An anatomic and hemodynamic study of the vascularized pig fibula model. J. Otolaryngol. 25: 103, 1996.
20. Pang, C. Y., Neligan, P. C., and Nakatsuka, T. Assessment of microsphere technique for measurement of capillary blood flow in random skin flaps in pigs. Plast. Reconstr. Surg. 74: 513, 1984.
21. Gur, E., Chiodo, A. A., Pang, C. Y., et al. The vascularized pig fibula bone flap model: Effects of multiple segmental osteotomies and internal fixation on growth and viability. Plast. Reconstr. Surg. 103: 1436, 1999.
22. Teissier, J., Bonnel, F., and Allieu, Y. Vascularization, cellular behavior, and union of vascularized bone grafts: Experimental study in the rabbit. Ann. Plast. Surg. 14: 494, 1985.
23. Trotman, N., and Kelly, W. D. The effect of sympathectomy on blood flow to bone. J.A.M.A. 183: 123, 1963.
24. Brookes, M., Richards, D. J., and Singh, M. Vascular sequelae of experimental osteotomy. Angiology 21: 355, 1970.
25. Weiland, A. J., Berggren, A., and Jones, L. The acute effects of blocking medullary blood supply on regional cortical blood flow in canine ribs as measured by the hydrogen washout technique, Clin. Orthop. 165: 265, 1982.
26. Whiteside, L. A., Lesker, P. A., and Simmons, D. J. Measurement of regional bone and bone marrow blood flow in the rabbit using the hydrogen washout technique. Clin. Orthop. 122: 340, 1977.
27. Berggren, A., Weiland, A. J., Ostrup, L. T., and Dorfman, H. Microvascular free bone transfer with revascularization of the medullary and periosteal circulation or the periosteal circulation alone: A comparative experimental study. J. Bone Joint Surg. Am. 64: 73, 1982.
28. Strachan, R. K., McCarthy, I., Fleming, R., and Hughes, S. P. F. The role of the tibial nutrient artery: Microsphere estimation of blood flow in the osteotomised canine tibia. J. Bone Joint Surg. Br. 72: 391, 1990.
29. Trias, A., and Fery, A. Cortical circulation of long bones. J. Bone Joint Surg. Am. 61: 1052, 1979.
30. Rhinelander, F. W. The normal microcirculation of diaphyseal cortex and its response to fracture. J. Bone Joint Surg. Am. 50: 784, 1968.
31. MacNab, I., and de Haas, W. G. The role of periosteal blood supply in the healing of fractures of the tibia. Clin. Orthop. 105: 27, 1974.
32. Schemitsch, E. H., Weinberg, J. A., McKee, M. D., and Richards, R. R. The relative importance of intramedullary, intracortical, and extraosseous soft-tissue blood flow to the repair of the devascularized canine tibial cortex. Ann. Plast. Surg. 38: 623, 1997.
33. Wallace, A. L., Draper, E. R. C., Strachan, R. K., McCarthy, I. D., and Hughes, S. P. F. The effect of devascularisation upon early bone healing in dynamic external fixation. J. Bone Joint Surg. Br. 73: 819, 1991.
34. Gustilo, R. B., Mendoza, R. M., and Williams, D. N. Problems in the management of type III (severe) open fractures: A new classification of type III open fractures. J. Trauma 24: 742, 1984.
35. Byrd, H. S., Cierny, G., III, and Tebbetts, J. B. The management of open tibial fractures associated with soft-tissue loss: External pin fixation with early flap coverage. Plast. Reconstr. Surg. 68: 73, 1981.
36. Kregor, P. J., Senft, D., Parvin, D., et al. Cortical bone perfusion in plated fractured sheep tibiae. J. Orthop. Res. 13: 715, 1995.
37. Smith, S. R., Bronk, J. T., and Kelly, P. J. Effect of fracture fixation on cortical bone blood flow. J. Orthop. Res. 8: 471, 1990.
38. Schemitsch, E. H., Kowalski, M. J., Swiontkowski, M. F., and Senft, D. Cortical bone blood flow in reamed and unreamed locked intramedullary nailing: A fractured tibia model in sheep. J. Orthop. Trauma 8: 373, 1994.
39. Berggren, A., Weiland, A. J., and Dorfman, H. The effect of prolonged ischemia time on osteocyte and osteoblast survival in composite bone grafts revascularized by microvascular anastomoses. Plast. Reconstr. Surg. 69: 290, 1982.