Histochemical demonstration of changes in the activity of hepatic phosphatases induced by experimental lead poisoning in male white rats (Rattus norvegicus)

Toxicology and Industrial Health

Volumn 16, Issue 1, 2000, Pages 7-15

  Jarrar, Bashir M ^a   Mahmoud, Zuheir N ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b UNIVERSITY OF KHARTOUM   (Sudan)

Author keywords

histochemistry; lead; liver; phosphatases; rat

Indexed keywords

LEAD ACETATE; LIVER ENZYME; PHOSPHATASE;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; LEAD POISONING; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; RAT;

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; ANIMALS; HISTOCYTOCHEMISTRY; LEAD; LEAD POISONING; LIVER; MALE; MITOCHONDRIA, LIVER; NA(+)-K(+)-EXCHANGING ATPASE; NUCLEOTIDASES; ORGANOMETALLIC COMPOUNDS; PHOSPHORIC MONOESTER HYDROLASES; RATS; RATS, WISTAR;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0034013547     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/074823370001600102     Document Type: Article

References (49)

1. Allen P. Chronic accumulation of cadmium in the edible tissues of Oreochromis aureus (Steindachner): modification by mercury and lead. Arch. Environ. Contam. Toxicol. 1995: 29: 8-14.
2. Andersen B., Zierz S., and Jungermann K. Alteration in zonation of succinate dehydrogenase, phosphoenolpyruvate carboxykinase and glucose-6-phosphatase in regeneration rat liver. Histochemistry 1984: 80: 97-101.
3. Arizono K., Sugiura S., Miyazato S., Takiguchi M., and Ariyoshi T. DT-diaphorase induction by lead acetate in the liver of rats. Bull. Environ. Contam. Toxicol. 1996: 57 (1): 41-46.
4. Aronson A. L. Outbreaks of Plumbism in animals associated with industrial lead operations. In: Oehme F. W., (Ed.), Toxicology of Heavy Metals in the Environment. Macmillan Publishing Co. New York, 1978, pp. 173–177.
5. Bancroft J. D., and Stevens A. Theory and Practice of Histological Techniques, 2nd edn. Churchill Livingstone, London, 1986, 662-662 pp.
6. Blakley B. R. A retrospective study of lead poisoning in cattle. Vet. Hum. Toxicol. 1984: 26: 505-507.
7. Brun A., and Brunk U. Lead induced injury on in vitro cultured rat fibroblasts. A histochemical study. Histochemie 1973: 35: 227-234.
8. Dawson T. P., Gandhi R., Hir M. L., and Kaissling B. Ecto-5-nucleotidase: localization in rat kidney by light microscopic histochemical and immunohistochemical methods. J. Histochim. Cytochem. 1989: 37: 39-47.
9. Fantin A., Frachini A., Trevisan P., and Pedezoli A. Histomorphological changes induced in the liver goldfish Carassius carassius Var. auratus by short-term exposure to lead. Acta Histochem. 1992: 92 (2): 228-235.
10. Filipe M. I., and Lake B. D. Histochemistry in Pathology. Churchill Livingstone, London, 1983, 349-349 pp.
11. Flora S., Kumar D., and Sachan S. Combined exposure to lead and ethanol on tissue concentration of essential metals and some biochemical indices in rat. Biol. Trace Elem. Res. 1991: 28: 127-164.
12. Fowler B. A., Kimmel C. A., Wood J. S., Ernest E. M., and Grant L. D. Chronic low-level lead toxicity in the rat. An integrate assessment of long-toxicity with special reference to kidney. Toxicol. Appl. Pharmacol. 1980: 56: 59-59.
13. Fox D., Rubinstein H., and Hsu P. Developmental lead exposure inhibits adult rat retinal, but not kidney Na+—K+ -ATPase. Toxicol. Appl. Pharmacol. 1991: 109 (3): 482-493.
14. Goyer R. A., and Krall R. Ultrastructural transformation in mitochondria isolated from kidneys of normal and lead intoxicated rats. J. Cell Biol. 1969: 41: 393-400.
15. Grandjean P. Organolead compounds. Environment health aspects. Residue Rev. 1979: 72: 97-148.
16. Hamir A. N. Review of lead poisoning in dogs. Vet. Bull. 1986: 56: 1059-1067.
17. Hardonk M. J. 5-Nucleotidase: I. Distribution of 5-nucleotidase in tissue of rat and mouse. Histochemie 1968: 12: 1-17.
18. Kanamura S., Kanai K., and Asada-Kutbota M. Cytochemical localization of glucose-6-phosphatase activity in membranes of the endoplasmic reticulum and nuclear envelope in mouse hepatocyte. Acta Histochem. Cytochem. 1982: 15 (1): 108-115.
19. Keino H., Shimzu K., and Mizutani A. Fine structural study of acid phosphatase act in the Kupffer cells of anemic mice. Acta Histochem. Cytochem. 1984: 17 (6): 615-621.
20. Khan M., Szarek J., Krasnodebska-Depta A., and Koncicki A. Effect of concurrent administration of lead and selenium on some haematological and biochemical parameters or broiler chickens. Acta. Vet. Hung. 1993: 41 (1-2): 123-137.
21. Kowalczyk D. F. Lead poisoning in dogs at the university of Pennsylvania Veterinary Hospital. J. Am. Vet. Med. Assoc. 1976: 168: 428-432.
22. Kowalczyk D. F. Lead poisoning. In: Krik R. W. (Ed.), Current Veterinary Therapy: Small Animal Practice. W.B. Saunder Co., Philadelphia, 1986, pp. 145–150.
23. Mayahara H., Hirano H., Saito T., and Orgawa K. The new lead citrate method for the ultracytochemical demonstration of non-specific alkaline phosphatase (Orthophosphoric monoester phosphohydrolase). Histochemie 1967: 11: 88-88.
24. Morgan R. V., Moore F. M., and Pearce L. K. Clinical and laboratory findings in small companion animals with lead poisoning: 347 cases (1977-1986). JAVMA 1991: 199 (1): 93-97.
25. Nehru B., and Kaushal S. Alterations in the hepatic enzymes following experimental lead poisoning. Biol. Trace Elem. Res. 1993: 38: 27-34.
26. Pearse A. G. E. Histochemistry. Theoretical and Applied, 3rd edn. Churchill Livingstone, London, 1972, 1518-1518 pp.
27. Rajanna B., Chetty C., Stewart T., and Rajana S. Effects of lead on pH and temperature-dependent substrate activation kinetics of ATPase system and it's protection by thiol compounds in rat brain. Biomed. Environ. Sci. 1991: 4 (4): 441-451.
28. Rijhsinghani K., Choi H., Burton L., Paronetto F., and Tavoloni N. Immunoelectron microscopy identification of early proliferating cells in rat liver tissue during hyperplasia induced by lead nitrate. Hepatology 1993: 17 (4): 685-692.
29. Sandhir R., and Gill K. Effect of lead on lipid peroxidation in liver of rat. Biol. Trace Elem. Res. 1995: 48: 281-288.
30. Sasse D., Teutsch H. F., Katz N., and Jungermann K. Arbeitsteilung and adaptive Gesamteistung des leberparenchyme Histochemiche und biochemische untersuchungen Zum Kohlenhydratstoffwechsel. Verh. Anat. Ges. 1977: 71: 873-877.
31. Sherlock S., and Dooley J. Diseases of the Liver and Biliary System, 9th edn. Blackwell Scientific Publication, London, 1993.
32. Shinozuka H., Ohmura T., Katyal S., Zedda A., Ledda-Columbano G., and Columbano A. Possible roles of nonparenchymal cells in hepatocyte proliferation induced by lead nitrate and by tumor necrosis factor alpha. Hepatology 1996: 23 (8): 1572-1577.
33. Shy C. M. Lead in petrol: the mistake of the xxth century. World Health Stat. Q. 1990: 43: 168-175.
34. Singh B., Dhawan D., Nehru B., Garg M., Mangal P., Chand B., and Trehan P. Impact of lead pollution on the status of other trace metals in the alterations in hepatic functions. Biol. Trace Elem. Res. 1994: 40 (1): 21-29.
35. Singhal R. L., Kacew S., Sutherland D. B., and Telli A. H. Plumbism: adaptive changes in hepatic and renal metabolism. Res. Commun. Chem. Pathol. Pharmacol. 1973: 6 (3): 951-962.
36. Takemoto F. Ultracytochemical changes of glucose-6-phosphatase activity in degenerative hepatocytes in chronic hepatitis. Application of glucose-6-phosphatase ultracytochemistry to human liver. Acta Histochem. Cytochem. 1979: 12 (5): 423-433.
37. Teutsch H. F. Improved method for histochemical demonstration of glucose-6-phosphatase activity. Histochemistry 1978: 57: 107-117.
38. Teutsch H. F. Functional liver heterogeneity. Acta Histochem. Cytochem. 1984: 17 (6): 687-687.
39. Thrivikraman K. V., Agrawal R., and Randhave R. Effect of lead toxicity on ascorbic acid content of liver and brain in albino rats fed low and high protein diets. The Ind. J. Nutr. Diet. 1978: 15: 200-204.
40. Tsafaris F., and Alexaki E. The transplacental effect of lead compounds on inorganic pyrophosphatase in brain, liver and kidneys of newborn rats. Vet. Hum. Toxicol. 1992: 34 (6): 510-512.
41. Tulas S. J., Reddy U. M., and Ramanarao J. V. Accumulation of lead and effects on total lipids and lipid derivatives in freshwater fish Anabas testudineus. Ecototoxicology and Environmental Safety 1992: 23: 33-38.
42. UNEP List of environmentally dangerous chemical substances and processes of global significance. International Register for Potentially Toxic Chemicals, United Nations Environment Programme, 1984.
43. Valle B. L., and Ulmer D. Lead Toxicity. Annu. Rev. Biochem. 1972: 41: 91-91.
44. Van Noorden C. F., and Frederiks W. M. Enzyme histochemistry. A Laboratory Manual of Current Methods. Oxford Univ. Press, Oxford, 1992.
45. Wachstein M., and Meisel E. Histochemistry of hepatic phosphatases at physiologic pH with special reference to the demonstration of the canaliculi. Am. J. Clin. Pathol. 1957: 27: 13-23.
46. Wachstein M., Bradshaw M., and Ortiz J. M. Histochemical demonstration of mitochondrial adenosine triphosphatase activity in tissue solutions. J. Histochem. Cytochem. 1962: 10: 63-74.
47. Wapnir R. A., Exeni R. A., McVicar M., and Lefshitz F. Experimental lead poisoning and intestinal transport of glucose, amino acids and sodium. Pediatr. Res. 1977: 11: 153-157.
48. Yamamoto K., Mayahara H., and Ogawa K. Cytochemical localization of Ouabain-sensitive, K-dependent P-nitrophenyl phosphatase in the rat hepatocytes. Acta Histochem. Cytochem. 1982: 17 (1): 23-35.
49. Zook B. C., Carpenter J. L., and Roberts R. M. Lead poisoning in dogs: occurrence, source, clinical pathology and electron-cephalography. Am. J. Vet. Res. 1972: 33: 891-902.