Murine Myak, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system

Molecular Reproduction and Development

Volumn 55, Issue 4, 2000, Pages 372-378

  Shang, Enyuan ^a,b   Wang, Xiangyuan ^a   Huang, Jinghong ^a   Yoshida, Wataru ^c   Kuroiwa, Atsushi ^c   Wolgemuth, Debra J ^a  

^a Columbia Univ Coll Phys Surgs ^*  (United States)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c College of Physicians and Surgeons ^*

Author keywords

Hormone modulation; In situ hybridization; Mouse embryos; Protein kinase; Transcription complexes

Indexed keywords

HOMEODOMAIN PROTEIN; PROTEIN KINASE;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CORPUS LUTEUM; EMBRYO; EPIDIDYMIS; EPITHELIUM; GENE EXPRESSION; GENITAL SYSTEM; IN SITU HYBRIDIZATION; MAMMARY GLAND; MOUSE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS; SPERMATID; UTERUS;

NON-PROGRAMMATIC;

ANIMALS; BLOTTING, NORTHERN; CENTRAL NERVOUS SYSTEM; EPITHELIUM; FEMALE; GENITALIA; HORMONES; IN SITU HYBRIDIZATION; KIDNEY; MALE; MAMMARY GLANDS, ANIMAL; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; OVARY; PHYLOGENY; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TESTIS; UTERUS;

ANIMALIA; FUNGI; MURINAE; MYXOGASTRIA;

EID: 0034012798     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2795(200004)55:4<372::AID-MRD3>3.0.CO;2-A     Document Type: Article

References (23)

1. Becker W, Weber Y, Wetzel K, Eirmbter K, Tejedor FJ, Joost HG. 1998. Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. J Biol Chem 273:25893-25902.
2. Begley DA, Berkenpas MB, Sampson KE, Abraham I. 1997. Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1. Gene 200:35-43.
3. Chapman DL, Wolgemuth DJ. 1992. Identification of a mouse B-type cyclin which exhibits developmentally regulated expression in the germ line. Mol Reprod Dev 33:259-69.
4. Chen H, Antonarakis SE. 1997. Localization of a human homologue of the Drosophila mnb and rat Dyrk genes to chromosome 21q22.2. Hum Genet 99:262-265.
5. Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
6. Garrett S, Broach J. 1989. Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase. Genes Dev 3:1336-1348.
7. Garrett S, Menold MM, Broach JR. 1991. The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle. Mol Cell Biol 11:4045-4052.
8. Guimera J, Casas C, Pucharcos C, Solans A, Domenech A, Planas AM, Ashley J, Lovett M, Estivill X, Pritchard MA. 1996. A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region. Hum Mol Genet 5:1305-1310.
9. Hartley AD, Ward MP, Garrett S. 1994. The Yak1 protein kinase of Saccharomyces cerevisiae moderates thermotolerance and inhibits growth by an Sch9 protein kinase-independent mechanism. Genetics 136:465-474.
10. Kentrup H, Becker W, Heukelbach J, Wilmes A, Schurmann A, Huppertz C, Kainulainen H, Joost HG. 1996. Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII. J Biol Chem 271:3488-3495.
11. Kim YH, Choi CY, Lee SJ, Conti MA, Kim Y. 1998. Homeodomain-interacting protein kinases, a novel family of Co-repressors for homeodomain transcription factors. J Biol Chem 273:25875-25879.
12. Moilanen AM, Karvonen U, Poukka HOA Jn, Palvimo JJ. 1998. Activation of androgen receptor function by a novel nuclear protein kinase. Mol Biol Cell 9:2527-2543.
13. Ohira M, Seki N, Nagase T, Suzuki E, Nomura N, Ohara O, Hattori M, Sakaki Y, Eki T, Murakami Y, Saito T, Ichikawa H, Ohki M. 1997. Gene identification in 1.6-Mb region of the Down syndrome region on chromosome 21. Genome Res 7:47-58.
14. Rechsteiner M, Rogers SW. 1996. PEST sequences and regulation by proteolysis. Trends Biochem Sci 21:267-271.
15. Rhee K, Wolgemuth DJ. 1997. The NIMA-related kinase 2, Nek2, is expressed in specific stages of the meiotic cell cycle and associates with meiotic chromosomes. Development 124:2167-2177.
16. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular cloning. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
17. Shindoh N, Kudoh J, Maeda H, Yamaki A, Minoshima S, Shimizu Y, Shimizu N. 1996. Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from "the Down syndrome critical region" of chromosome 21. Biochem Biophys Res Commun 225:92-99.
18. Smith DJ, Stevens ME, Sudanagunta SP, Bronson RT, Makhinson M, Watabe AM, TJ OD, Fung J, Weier HU, Cheng JF, Rubin EM. 1997. Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome. Nat Genet 16:28-36.
19. Song WJ, Sternberg LR, Kasten-Sportes C, Keuren ML, Chung SH, Slack AC, Miller E, Glover TW, Chiang PW, Lou L, Kurnit DM. 1996. Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region." Genomics 38:331-339.
20. Song WJ, Chung SH, Kurnit DM. 1997. The murine Dyrk protein maps to chromosome 16, localizes to nucleus, and can form multimers. Biochem Biophys Res Comm 231:640-644.
21. Souza GM, Lu S, Kuspa A. 1998. YakA, a protein kinase required for the transition from growth to development in Dictyostelium. Development 125:2291-2302.
22. Swofford DL. 1993. PAUP 3.1.1: phylogenetic analysis using parsimony. Champaign, IL: Center for Biodiversity, Illinois Natural History Survey.
23. Tejedor F, Zhu XR, Kaltenbach E, Ackermann A, Baumann A, Canal I, Heisenberg M, Fischbach KF, Pongs O. 1995. Minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila. Neuron 14:287-301.