Alcohol-related diarrhea

Addiction Biology

Volumn 5, Issue 2, 2000, Pages 117-125

  Chiba, Toshimi ^a   Phillips, Sidney F ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL;

ALCOHOLISM; ATROPHIC GASTRITIS; BACTERIAL OVERGROWTH; DIARRHEA; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRACT FUNCTION; HUMAN; INTESTINE ABSORPTION; INTESTINE INNERVATION; INTESTINE MUCOSA; INTESTINE TRANSIT TIME; INTESTINE VILLUS; PANCREAS SECRETION; PRIORITY JOURNAL; REVIEW; SMALL INTESTINE; STOMACH; STOMACH EMPTYING;

EID: 0034012669     PISSN: 13556215     EISSN: None     Source Type: Journal    
DOI: 10.1080/13556210050003702     Document Type: Review

References (113)

1. 1. Gaziano JM, Buring JE, Breslow JL et al. Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarction. N Engl J Med 1993; 329:1829-34.
2. 2. Zakhari S, Gordis E. Moderate drinking and cardiovascular health. Proc Assoc Am Physicians 1999;111:148-58.
3. 3. Chari ST, Teyssen S, Singer MV. What controls should be used in studies of acute effects of alcohol and alcoholic beverages on the stomach and the pancreas? Scand J Gastroenterol 1993;28: 289-95.
4. 4. Gitlow SE, Seixas FA. The medical complications of alcoholism. In: Gitlow SE, Peyser HS, editors. Alcoholism: a practical treatment guide. Philadelphia: Grune and Stratton; 1988, pp. 124-41.
5. 5. Cyr MG, Moult on AW. The gastrointestinal tract and pancreas. In: Barnes HN, Aronson MD, Delbanco TL, editors. Alcoholism: a guide for the primary care physician. New York: Springer-Verlag; 1987, pp. 127-33.
6. 6. Burbige EJ, Lewis DR Jr, Halsted CH. Alcohol and the gastrointestinal tract. Med Clin North Am 1984;68:77-89.
7. 7. Kvietys PR, Patterson WG, Russell JM, Barrowman JA, Granger DN. Role of the microcirculation in ethanol-induced mucosal injury in the dog. Gastroenterology 1984;87:562-71.
8. 8. Krasner N, Cochran KM, Russell RI, Carmichael HA, Thompson GG. Alcohol and absorption from the small intestine. 1. Impairment of absorption from the small intestine in alcoholics. Gut 1976; 17:245-8.
9. 9. Dinda PK, Beck IT, Beck M, McElligott TF. Effect of ethanol on sodium-dependent glucose transport in the small intestine of the hamster. Gastroenterology 1975;68:1517-26.
10. 10. Gottfried EB, Korsten MA, Lieber CS. Alcohol-induced gastric and duodenal lesions in man. Am J Gastroenterol 1978;70:587-92.
11. 11. Dinda PK, Leddin DJ, Beck IT. Histamine is involved in ethanol-induced jejunal microvascular injury in rabbits. Gastroenterology 1988;95: 1227-33.
12. 2 alleviates jejunal microvascular effects of ethanol but not the ethanol-induced inhibition of water, sodium, and glucose absorption. Gastroenterology 1988; 94:726-32.
13. 13. Colombel JF, Hällgren R, Venge P, Mesnard B, Rambaud JC. Neutrophil and eosinophil involvement of the small bowel affected by chronic alcoholism. Gut 1988;29:1656-60.
14. 14. Fox JE, Bourdages R, Beck IT. Effect of ethanol on glucose and water absorption in hamster jejunum in vivo. Methodological problems: anesthesia, nonabsorbable markers, and osmotic effect. Am J Dig Dis 1978;23:193-200.
15. 15. Kuo Y-J, Shanbour LL. Effects of ethanol on sodium, 3-O-methyl glucose, and L-alanine transport in the jejunum. Am J Dig Dis 1978;23: 51-6.
16. 16. Wilson FA, Hoyumpa AM Jr. Ethanol and small intestinal transport. Gastroenterology 1979;76: 388-403.
17. 17. O'Neill B, Weber F, Hornig D, Semenza G. Ethanol selectively affects Na + -gradient dependent intestinal transport system. FEBS Lett 1986; 194:183-8.
18. 18. Worthington BS, Meserole L, Syrotuck JA. Effect of daily ethanol ingestion on intestinal permeability to macromolecules. Am J Dig Dis 1978;23: 23-32.
19. +)-ATPase. Biochim Biophys Acta 1973; 311:417-22.
20. 20. Bjarnason I, Ward K, Peters TJ. The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet 1984;1:179-82.
21. 21. Stern M, Carter EA, Walker WA. Food proteins and gut mucosal barrier. IV. Effects of acute and chronic ethanol administration on handling and uptake of bovine serum albumin by rat small intestine. Dig Dis Sci 1986;31:1242-8.
22. 22. Bode JC, Bode C, Heidelbach R, Dürr H-K, Martini GA. Jejunal microflora in patients with chronic alcohol abuse. Hepatogastroenterology 1984;31:30-4.
23. 23. Baraona E, Julkunen R, Tannenbaum L, Lieber CS. Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats. Gastroenterology 1986;90:103-10.
24. 24. Lerler J, Brumberger V, Preac-Mursic V. Severe diarrhea associated with Arcobacter butzleri. Eur J Clin Microbiol Infect Dis 1994;13:660-2.
25. 25. Jokelainen K, Matysiak-Budnik T, Mäkisalo H, Höckerstedt K, Salaspuro M. High intracolonic acetaldehyde values produced by a bacteriocolonic pathway for ethanol oxidation in piglets. Gut 1996;39:100-4.
26. 26. Nosova T, Jokelainen K, Kaihovaara P et al. Aldehyde dehydrogenase activity and acetate production by aerobic bacteria representing the normal flora of human large intestine. Alcohol Alcohol 1996;31:555-64.
27. 27. Lembcke B, Kraus B, Lankisch PG. Small intestinal function in chronic relapsing pancreatitis. Hepatogastroenterology 1985;32:149-51.
28. 28. Bode C, Kolepke R, Schäfer K, Bode JC. Breath hydrogen excretion in patients with alcoholic liver disease - evidence of small intestinal bacterial overgrowth. Z Gastroenterol 1993;31:3-7.
29. 29. Koivisto T, Salaspuro M. Adehyde dehydrogenases of the rat colon: comparison with other tissues of the alimentary tract and the liver. Alcohol Clin Exp Res 1996;20:551-5.
30. 30. Nosova T, Jousimies-Somer H, Kaihovaara P, Jokelainen K, Heine R, Salaspuro M. Characteristics of alcohol dehydrogenases of certain aerobic bacteria representing human colonie flora. Alcohol Clin Exp Res 1997;21:489-94.
31. 31. Visapaa JP, Jokelainen K, Nosova T, Salaspuro M. Inhibition of intracolonic acetaldehyde production and alcoholic fermentation in rats by ciprofloxacin. Alcohol Clin Exp Res 1998;22: 1161-4.
32. 32. Martin JL, Justus PG, Mathias JR. Altered motiliry of the small intestine in response to ethanol (ETOH): an explanation for the diarrhea associated with the consumption of alcohol [abstract]. Gastroenterology 1980;78:1218.
33. 33. Wegener M, Schaffstein J, Dilger U, Coenen C, Wedmann B, Schmidt G. Gastrointestinal transit of solid-liquid meal in chronic alcoholics. Dig Dis Sci 1991;36:917-23.
34. 34. Papa A, Tursi A, Cammarota G et al. Effect of moderate and heavy alcohol consumption on intestinal transit time. Panminerva Med 1998;40: 183-5.
35. 35. Perlow W, Baraona E, Lieber CS. Symptomatic intestinal disaccharidase deficiency in alcoholics. Gastroenterology 1977;72:680-4.
36. 36. Linscheer WG. Malabsorption in cirrhosis. Am J Clin Nutr 1970;23:488-92.
37. 37. de las Heras Casstano G, Sanchez Antolin G, Duenas, Sadornil C, de la Pena Garcia J, Pons Romero F. Relationship between the presenting symptoms and age at diagnosis in alcoholic and nonalcoholic chronic pancreatitis: analysis of 164 patients. Rev Esp Enferm Dig 1997;89:269-79.
38. 35 S-thiamine hydrochloride absorption in the malnourished alcoholic patient. J Lab Clin Med 1970;76:34-45.
39. 39. Lindenbaum J, Lieber CS. Effects of chronic ethanol administration on intestinal absorption in man in the absence of nutritional deficiency. Ann NY Acad Sci 1975;252:228-34.
40. 40. Leevy CM, Baker H. Vitamins and alcoholism. Am J Clin Nutr 1968;21:1325-8.
41. 3H-PGA) in alcoholic patients: roles of alcohol and nutrition. N Engl J Med 1971;285:701-6.
42. 42. Hoyumpa AM. Mechanisms of vitamin deficiencies in alcoholism. Alcohol Clin Exp Res 1986;10:573-81.
43. 43. Said HM, Strum WB. Effect of ethanol and other aliphatic alcohols on the intestinal transport of folates. Digestion 1986;35:129-35.
44. 44. Bode JC. Alcohol and the gastrointestinal tract. In: Frick P, von Harnack G-A, Martini GA, Prader A, editors. Advances in Internal Medicine Pediatrics. Berlin: Springer-Verlag; 1980, pp. 2-75.
45. 45. World MJ, Ryle PR, Thomson AD. Alcoholic malnutrition and the small intestine. Alcohol Alcohol 1985;20:89-124.
46. 46. Leevy CM, Baker H, tenHove W, Frank O, Cherrick GR. B-complex vitamins in liver disease of the alcoholic. Am J Clin Nutr 1965;16: 339-46.
47. 47. Hermos JA, Adams WH, Liu YK, Sullivan LW, Trier JS. Mucosa of the small intestine in folate-deficient alcoholics. Ann Intern Med 1972;76: 957-65.
48. 48. Beck IT, Dinda PK. Acute exposure of small intestine to ethanol. Effects on morphology and function. Dig Dis Sci 1981;26:817-38.
49. 50. Brozinsky S, Fani K, Grosberg SJ, Wapnick S. Regeneration of jejunal mucosa during recovery from malnutrition and pancreatic insufficiency. Am J Gastroenterol 1979;71:83-9.
50. 51. Sass H, Soyka M, Mann K, Zieglansberger W. Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence. Arch Gen Psychiatry 1996;53:673-80.
51. 52. Besson J, Aeby F, Kasas A, Lehert P, Potgieter A. Combined efficacy of acamprosate and disulfiram in the treatment of alcoholism: a controlled study. Alcohol Clin Exp Res 1998;22:573-9.
52. 53. Peppers MP. Benzodizepines for alcohol withdrawal in the elderly and in patients with liver disease. Pharmacotherapy 1996;16:49-57.
53. 54. Bouchoucha M, Nalpas B, Berger M, Cugnenc P-H, Barbier J-Ph. Recovery from disturbed colonic transit time after alcohol withdrawal. Dis Col Rectum 1991;34:111-14.
54. 55. Geall MG, Phillips SF, Summerskill WHJ. Profile of gastric potential difference in man. Effects of aspirin, alcohol, bile, and endogenous acid. Gastroenterology 1970;58:437-43.
55. 56. Palmer ED. Gastritis: a re-evaluation. Medicine 1954;33:199-290.
56. 57. Phillips SF. Pathophysiology of gastritis: recent concepts and clinical significance. South Med J 1972;65:1187-91.
57. 58. Dinoso VP, Chey WY, Siplet H, Lorber SH. Effects of ethanol on the gastric mucosa of the Heidenhain pouch of dogs. Am J Dig Dis 1970; 15:809-17.
58. 59. Baraona E, Pirola RC, Lieber CS. Small intestinal damage and changes in cell population produced by ethanol ingestion in the rat. Gastroenterology 1974;66:226-34.
59. 60. Parl FF, Lev R, Thomas E, Pitchumoni CS. Histologic and morphometric study of chronic gastritis in alcoholic patients. Hum Pathol 1979; 10:45-56.
60. 61. Rubin E, Rybak BJ, Lindenbaum J, Gerson CD, Walker G, Lieber CS. Ultrastructural changes in the small intestine induced by ethanol. Gastroenterology 1972;63:801-14.
61. 62. Persson J, Berg NO, Sjölund K, Stenling R, Magnusson P-H. Morphologic changes in the small intestine after chronic alcohol consumption. Scand J Gastroenterol 1990;25:173-84.
62. 63. Nano JL, Cefai D, Rampal P. Effects of ethanol on an intestinal epithelial cell line. Alcohol Clin Exp Res 1990;14:32-7.
63. 64. Lansdown ABG, Dayan AD. Alterations in crypt cell populations in the small intestine as an early toxic response to sub-acute ethanol administration. Arch Toxicol 1987;59:448-52.
64. 65. Sjölund K, Persson J, Bergman L. Can villous atrophy be induced by chronic alcohol consumption? J Intern Med 1989;226:133-5.
65. 66. Straus E, Urbach H-J, Yalow RS. Alcohol-stimulated secretion of immunoreactive secretin. N Engl J Med 1975;293:1031-2.
66. 67. Tiscornia OM, Gullo L, Sarles H et al. Effects of intragastric and intraduodenal ethanol on canine exocrine pancreatic secretion. Digestion 1974;10: 52-60.
67. 68. Pirola RC, Davis AE. The sphincter of Oddi and pancreatitis. Am J Dig Dis 1970;15:583-8.
68. 69. Greene HL, Stifel FB, Herman RH, Herman YF, Rosensweig NS. Ethanol-induced inhibition of human intestinal enzyme activities: reversal by folic acid. Gastroenterology 1974;67:434-40.
69. 70. Draper LR, Gyure LA, Hall JG, Robertson D. Effect of alcohol on the integrity of the intestinal epithelium. Gut 1983;24:399-404.
70. 71. Talbot RW, Foster JR, Hermon-Taylor J, Grant DAW. Induced mucosal penetration and transfer to portal blood of luminal horseradish peroxidase after exposure of mucosa of guinea pig small intestine to ethanol and lysolecithin. Dig Dis Sci 1984;29:1015-22.
71. 72. Carter EA, Harmatz PR, Udall JN, Walker WA. Barrier defense function of the small intestine: effect of ethanol and acute burn trauma. Adv Exp Med Biol 1987;216A:829-33.
72. 73. Mekhjian HS, May ES. Acute and chronic effects of ethanol on fluid transport in the human small intestine. Gastroenterology 1977;72:1280-6.
73. 74. Mezey E, Jow E, Slavin RE, Tobon F. Pancreatic function and intestinal absorption in chronic alcoholism. Gastroenterology 1970;59:657-64.
74. 75. Roggin GM, Iber FL, Linscheer WG. Intraluminal fat digestion in the chronic alcoholic. Gut 1972;13:107-11.
75. 76. Mazzanti R, Debnam ES, Jenkins WJ. Effect of chronic ethanol intake on lactase activity and active galactose absorption in rat small intestine. Gut 1987;28:56-60.
76. 77. Dinda PK, Beck IT. On the mechanism of the inhibitory effect of ethanol on intestinal glucose and water absorption. Am J Dig Dis 1977;22: 529-33.
77. 78. Thomson ABR. Effect of chronic ingestion of ethanol on in vitro uptake of lipids and glucose in the rabbit jejunum. Am J Physiol 1984;246: G120-9.
78. 79. Roggin GM, Iber FL, Kater RMH, Tabon F. Malabsorption in the chronic alcoholic. Johns Hopkins Med J 1969;125:321-30.
79. 80. Persson J. Alcohol and the small intestine. Scand J Gastroenterol 1991;26:3-15.
80. 81. Nakada T, Knight RT. Alcohol and the central nervous system. Med Clin North Am 1984; 68:121-31.
81. 82. Victor M. Deficiency diseases of the nervous system secondary to alcoholism. Postgrad Med 1971;50:75-9.
82. 83. Wallis WE, Willoughby E, Baker P. Coma in the Wernicke-Korsakoff syndrome. Lancet 1978;2: 400-1.
83. 84. D'Amour ML, Shahani BT, Young RR, Bird KT. The importance of studying sural nerve conduction and late responses in the evaluation of alcoholic subjects. Neurology 1979;29:1600-4.
84. 85. Willer JC, Dehen H. Respective importance of different electrophysiological parameters in alcoholic neuropathy. J Neurol Sci 1977;33:387-96.
85. 86. Torvik A, Lindboe CF, Rogde S. Brain lesions in alcoholics. J Neurol Sci 1982;56:233-48.
86. 87. Carlen PL, Wilkinson DA, Wortzman G et al. Cerebral atrophy and functional deficits in alcoholics without clinically apparent liver disease. Neurology 1981;31:377-85.
87. 88. Ron MA, Acker W, Shaw GK, Lishman WA. Computerized tomography of the brain in chronic alcoholism. Brain 1982;105:497-514.
88. 89. Duncan G, Johnson RH, Lambie DG, Whiteside EA. Evidence of vagal neuropathy in chronic alcoholics. Lancet 1980;2:1053-7.
89. 90. Villalta J, Estrúch R, Antunez E, Valls J, Urbano-Márquez A. Vagal neuropathy in chronic alcoholics: relation to ethanol consumption. Alcohol Alcohol 1989;24:421-8.
90. 91. Camilleri M, Ford MF. Integrative neurohormonal control of gut function. In: Sharman DJC, Finlayson NDC, editors. Disease of the gastrointestinal tract and liver. New York: Churchill Livingstone; 1997, pp. 153-63.
91. 92. Keshavarzian A, Jacyno M, Urban G, Winship D, Fields JZ. The role of nitric oxide in ethanol-induced gastrointestinal dysfunction. Alcohol Clin Exp Res 1996;20:1618-24.
92. 93. Hogan WJ, Viegas de Andrade SR, Winship DH. Ethanol-induced acute esophageal motor dysfunction. J Appl Physiol 1972;32:755-60.
93. 94. Winship DH, Caflisch CR, Zboralske FF, Hogan WJ. Deterioration of esophageal peristalsis in patients with alcoholic neuropathy. Gastroenterology 1968;55:173-8.
94. 95. Keshavarzian A, Iber FL, Ferguson Y. Esophageal manometry and radionuclide emptying in chronic alcoholics. Gastroenterology 1987;92:651-7.
95. 96. Sanders KM, Bauer AJ. Ethyl alcohol interferes with excitation-contraction mechanisms of canine antral muscle. Am J Physiol 1982;242: G222-30.
96. 97. Sanders KM, Berry RG. Effects of ethyl alcohol on phasic and tonic contractions of the proximal stomach. J Pharmacol Exp Ther 1985;235: 858-63.
97. 98. Scroggs R, Abruzzo M, Advokat C. Effects of ethanol on gastrointestinal transit in mice. Alcohol Clin Exp Res 1986;10:452-6.
98. 99. Kaufman SE, Kaye MD. Effect of ethanol upon gastric emptying. Gut 1979;20:688-92.
99. 100. Jian R, Cortot A, Ducrot F, Jobin G, Chayvialle JA, Modigliani R. Effect of ethanol ingestion on postprandial gastric emptying and secretion, biliopancreatic secretions, and duodenal absorption in man. Dig Dis Sci 1986;31:604-14.
100. 101. Barboriak JJ, Meade RC. Effect of alcohol on gastric emptying in man. Am J Clin Nutr 1970;23: 1151-3.
101. 102. Moore JG, Christian PE, Datz FL, Coleman RE. Effect of wine on gastric emptying in humans. Gastroenterology 1981;81:1072-5.
102. 103. Cooke AR. The simultaneous emptying and absorption of ethanol from the human stomach. Am J Dig Dis 1970;15:449-54.
103. 104. Keshavarzian A, Iber FL, Greer P, Wobbleton J. Gastric emptying of solid meal in male chronic alcoholics. Alcohol Clin Exp Res 1986;10: 432-5.
104. 105. Iber FL. Alcohol and the gastrointestinal tract. Gastroenterology 1971;61:120-3.
105. 106. Lu G, Sarr MG, Szurszewski JH. Effects of ethyl alcohol on canine jejunal circular smooth muscle. Dig Dis Sci 1997;42:2403-10.
106. 107. Demol P, Singer MV, Hotz J et al. Action of intragastric ethanol on pancreatic exocrine secretion in relation to the interdigestive gastrointestinal motility in humans. Arch Int Physiol Biochim 1986;94:251-9.
107. 108. Charles F, Phillips SF. Effects of ethanol, xylose, and glucose on canine jejunal motility. Am J Physiol 1995;269:G363-9.
108. 109. Pirola RC, Davis AE. Effects of intravenous alcohol on motility of the duodenum and of the sphincter of Oddi. Aust Ann Med 1970;1:24-9.
109. 110. Robles EA, Mezey E, Halsted CH, Schuster M. Effect of ethanol on motility of the small intestine. Johns Hopkins Med J 1974;135:17-24.
110. 111. Pfeiffer A, Högl B, Kaess H. Effect of ethanol and commonly ingested alcoholic beverages on gastric emptying and gastrointestinal transit. Clin Invest 1992;70:487-91.
111. 112. Addolorato G, Montalto M, Capristo E et al. Influence of alcohol on gastrointestinal motility: lactulose breath hydrogen testing in orocecal transit time in chronic alcoholics, social drinkers and teetotaler subjects. Hepatogastroenterology 1997;44:1076-81.
112. 113. Berenson MM, Avner DL. Alcohol inhibition of rectosigmoid motility in humans. Digestion 1981; 22:210-5.
113. 114. Adler HF, Beazell JM, Atkinson AJ, Ivy AC. The motor response of the colon to alcohol. Q J Stud Alcohol 1941;10:638-44.