Biochemical and virological response to interferon therapy in patients with chronic hepatitis C, co-infected with hepatitis G virus

Journal of Viral Hepatitis

Volumn 7, Issue 1, 2000, Pages 43-50

  Shibahara, Nami ^a   Moriyama, M ^a   Abe, K ^b   Tanaka, N ^a   Arakawa, Y ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Chronic hepatitis C; HCV RNA; HGV RNA; Interferon; Response to interferon; Sequence

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALPHA INTERFERON; ALPHA2A INTERFERON; ASPARTATE AMINOTRANSFERASE; BETA INTERFERON; BILIRUBIN; GAMMA GLUTAMYLTRANSFERASE; HEPATITIS C ANTIBODY; RECOMBINANT ALPHA2B INTERFERON; VIRUS RNA;

ADULT; AGED; ARTICLE; BLOOD TRANSFUSION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEPATITIS C; HEPATITIS G VIRUS; HUMAN; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RELAPSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPERINFECTION; THROMBOCYTE COUNT;

5' UNTRANSLATED REGIONS; ADULT; AGED; ANTIVIRAL AGENTS; BASE SEQUENCE; FEMALE; FLAVIVIRIDAE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HEPATITIS, VIRAL, HUMAN; HUMANS; INTERFERONS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; RNA, VIRAL; TREATMENT OUTCOME;

EID: 0034011819     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2893.2000.00191.x     Document Type: Article

References (19)

1. 1 Simons JN, Leary TP, Dawson GJ et al. Isolation of a novel virus-like sequence associated with human hepatitis. Nature Med 1995; 1: 564-569.
2. 2 Linnen J, Wages J, Zhang-Keck Z-Y et al. Molecular cloning and disease association of hepatitis G virus: a transfusiontransmissible agent. Science 1996; 271: 505-508.
3. 3 Zuckerman AJ. Alphabet of hepatitis virus. Lancet 1996; 347: 558-559.
4. 4 Berg T, Darlia U, Naumann U et al. Responsiveness to interferon alpha treatment in patients with chronic hepatitis C coinfected with hepatitis G virus. J Hepatol 1996; 25: 763-768.
5. 5 Yoshiba M, Okamoto H, Mishiro S. Detection of GBV-C hepatitis virus genome in serum from patients with fulminant hepatitis of unknown aetiology. Lancet 1995; 346: 1131-1132.
6. 6 Tameda Y, Kosaka Y, Tagawa S et al. Infection with GB virus C (GBV-C) in patients with fulminant hepatitis. J Hepatol 1996; 25: 842-847.
7. 7 Moriyama M, Miyauchi I, Nakai K et al. HGV infection in Japanese patients with various forms of liver disease. 4th International Meeting on Hepatitis G Virus and Related Viruses-Molecular Virology and Pathogenesis. Kyoto, Japan, 1997.
8. 8 Matsumura H, Moriyama M. Shimojima M et al. Therapeutic effect of interferon on patients with type C chronic active hepatitis: comparison between complete responders and non responders. Nihon Univ Med 1997; 39: 267-276.
9. 9 Chomczynski P, Sachi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol -chloroform extraction. Anal Biochem 1987; 162: 156-159.
10. 10 Abe K, Moriyama M, Hayashi S et al. Prevalence of hepatitis G virus infection among patients with liver diseases in Japan. Int Hepatol Commun 1997; 6: 239-248.
11. 11 Lau JY, Davis GL, Knniffen J et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 1993; 341: 1501-1504.
12. 12 Kato N, Yokosuka O, Hosoda K, Ito Y, Ohto M, Omata M. Quantification of hepatitis C virus by competitive reverse transcription-polymerase chain reaction: increase of the virus in advanced liver disease. Hepatology 1993; 18: 16-20.
13. 13 Okamoto H, Sugiyama Y, Okada S et al. Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol 1992; 73: 673-679.
14. 14 Simmonds P, Alberti A, Alter H et al. A proposed system for the nomenclature of hepatitis C virus genotypes. Hepatology 1994; 19: 1 321-1324.
15. 15 Oshita M, Mita E, Hayashi N. Coinfection of hepatitis C virus and hepatitis G virus in patients with chronic hepatitis. Nippon Rinsho 1997; 55: 617-620.
16. 16 Tanaka E, Alter HJ, Nakatsuji Y et al. Effect of hepatitis G virus infection on chronic hepatitis C. Ann Intern Med 1996; 125: 740-743.
17. 17 Berenger M, Terrault NA, Piatak M et al. Hepatitis G virus infection in patients with hepatitis C virus infection undergoing liver transplantation. Gastroenterology 1996; 111: 1569-1575.
18. 18 Masuko K, Mitsui T, Iwano K et al. Infection with hepatitis GB virus C in patients on maintenance hemodialysis. N Engl J Med 1996; 334: 1485-1490.
19. 19 Saiz JC, Ampurdanes S, Olmed E et al. Hepatitis G virus infection in chronic hepatitis C: frequency, features and response to interferon therapy. J Hepatol 1997; 26: 787-793.