Validation of protein-based alignment in 3D quantitative structure- activity relationships with CoMFA models

European Journal of Medicinal Chemistry

Volumn 35, Issue 1, 2000, Pages 123-136

  Golbraikh, Alexander ^a   Bernard, Philippe ^a   Chrétien, Jacques R ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

3D QSAR; Acetylcholinesterase; Alzheimer's disease; CoMFA; Protein based alignment; Structure based alignment

Indexed keywords

CHOLINESTERASE INHIBITOR; PIPERIDINE DERIVATIVE;

ALZHEIMER DISEASE; ARTICLE; MODEL; MOLECULAR DYNAMICS; PREDICTION; PROTEIN CONFORMATION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

EID: 0034011785     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(00)00108-2     Document Type: Article

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