Age-dependent metabolic effects of repeated hypoxemia in piglets

Canadian Journal of Physiology and Pharmacology

Volumn 78, Issue 4, 2000, Pages 321-328

  Côté, Aurore ^a,b   Barter, Jill ^a   Meehan, Brian ^a  

^a Respiratory Medicine Division   (Canada)

^b MONTREAL CHILDREN S HOSPITAL   (Canada)

Author keywords

Catecholamines; Lactic acid; Maturation; Metabolic rate

Indexed keywords

ADRENALIN; CARBON DIOXIDE; CATECHOLAMINE; LACTIC ACID; NORADRENALIN;

ANIMAL EXPERIMENT; ARTERIAL CARBON DIOXIDE TENSION; ARTICLE; CATECHOLAMINE BLOOD LEVEL; CONTROLLED STUDY; HYPOXEMIA; LACTATE BLOOD LEVEL; LUNG VENTILATION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SWINE;

EID: 0034010718     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y99-141     Document Type: Article

References (30)

1. Barrington, K.J., Finer, N., and Li, D. 1996. Predischarge respiratory recordings in very low birth weight newborn infants. J. Pediatr. 129: 934-940.
2. 2 and β-adrenergic blockade. Am. J. Physiol. 217: 110-116.
3. Cheung, P.-Y., Barrington, K.J., Pearson, R.J., Bigam, D.L., Finer, N.N., and Van Aerde, E. 1997. Systemic, pulmonary and mesenteric perfusion and oxygenation effects of dopamine and epinephrine. Am. J. Crit. Care Med. 155: 32-37.
4. Côté, A., Blanchard, P.W., and Meehan, B. 1992. Metabolic and cardiorespiratory effects of doxapram and theophylline in sleeping newborn piglets. J. Appl. Physiol. 72: 410-415.
5. Côté, A., Porras, H., and Meehan, B. 1996. Age dependent vulnerability to carotid chemodenervation in piglets. J. Appl. Physiol. 80: 323-331.
6. Del Bigio, M.R., and Becker, L.E. 1994. Microglial aggregation in the dentate gyrus: a marker of mild hypoxic-ischemic brain insult in human infants. Neuropathol. Appl. Neurobiol. 20: 144-151.
7. Dickerson, J.W.T., and Dobbing, J. 1967. Prenatal and postnatal growth and development of the central nervous system of the pig. Proc. R. Soc. London Ser. B, 166: 384-395.
8. Duffy, T.E., Kohle, S.J., and Vannucci, R.C. 1974. Carbohydrate and energy metabolism in perinatal rat brain: relation to anoxia and survival. J. Neurochem. 24: 271-276.
9. Gillan, J.E., Curran, C., O'Reilly, E., Seamus, F.C., and Unwin, A.R. 1989. Abnormal patterns of pulmonary neuroendocrine cells in victims of sudden infant death syndrome. Pediatrics, 84: 828-834.
10. Glass, H.G., Snyder, F.F., and Webster, E. 1944. The rate of decline in resistance to anoxia of rabbits, dogs, and guinea pigs from the onset of viability to adult life. Am. J. Physiol. 140: 609-615.
11. Hunt, C.E. 1992. Sudden infant death syndrome. In Respiratory control disorders in infants and children. Edited by R.C. Beckerman, R.T. Brouillette, and C.E. Hunt. Williams and Wilkins, Baltimore, Md. pp. 190-211.
12. Jacobi, M.S., and Thach, B.T. 1989. Effect of maturation on spontaneous recovery from hypoxic apnea by gasping. J. Appl. Physiol. 66: 2384-2390.
13. Mayfield, K.P., and D'Alecy, L.G. 1992. Role of endogenous opioid peptides in the acute adaptation to hypoxia. Brain Res. 582: 226-231.
14. Mayfield, K.P., Hong, E.J., Carney, K.M., and D'Alecy, L.G. 1994. Potential adaptations to acute hypoxia: Hct, stress proteins, and set point for temperature regulation. Am. J. Physiol. 266: R1615-R1622.
15. Mitchell, E.A., Taylor, B.J., Ford, R.P.K., Stewart, A.W., Becroft, D.M.O., Thompson, J., Scragg, R., Hassall, I.B., Barry, D.M.J., Allen, E.M., and Roberts, A.P. 1992. Four modifiable and other major risk factors for cot death: the New Zealand study. J. Pediatr. Child. Health. (Suppl. 1), 28: S3-S8.
16. Moss, I.R., Runold, M., Dahlin, I., Fredholm, B.B., Nyberg, F., and Lagercrantz, H. 1987. Respiratory and neuroendocrine responses of piglets to hypoxia during postnatal development. Acta Physiol. Scand. 131: 533-541.
17. Nelson, E.A.S., Taylor, B.J., and Weatherall, I.L. 1989. Sleeping position and infant bedding may predispose to hyperthermia and the sudden infant death syndrome. Lancet, 304: 199-201.
18. Nioka, S., Smith, D.S., Mayevsky, A., Dobson, G.P., Veech, R.L., Subramanian, H., and Chance, B. 1991. Age dependence of steady state mitochondrial oxidative metabolism in the in vivo hypoxic dog brain. Neurol. Res. 13: 25-32.
19. Poets, C.F., Samuels, M.P., Noyes, J.P., Jones, K.A., and Southall, D.P. 1991. Home monitoring of transcutaneous oxygen tension in the early detection of hypoxemia in infants and young children. Arch. Dis. Child. 66: 676-682.
20. Poets, C.F., Samuels, M.P., Noyes, J.P., Hewerston, J., Hartmann, H., Holder, A., and Southall, D.P. 1993. Home event recordings of oxygenation, breathing movements, and heart rate and rythym in infants with recurrent life-threatening events. J. Pediatr. 123: 693-701.
21. Porras, H., Meehan, B., and Côté, A. 1995. Effect of theophylline on metabolic and ventilatory response to hypoxia in piglets. Pediatr. Res. 38: 926-931.
22. Rising, C.L., and D'Alecy, L.G. 1989. Hypoxia-induced increases in hypoxic tolerance by β-hydroxybutyrate in mice. Stroke, 20: 1219-1225.
23. Rognum, T.O., and Saugstad, O.D. 1991. Hypoxanthine levels in vitreous humor: evidence of hypoxia in most infants who died of sudden infants death syndrome. Pediatrics, 87: 306-310.
24. Rognum, T.O., Saugstad, O.D., Øyasæter, S., and Olaisen, B. 1988. Elevated levels of hypoxanthine in vitrous humor indicate prolonged cerebral hypoxia in victims of sudden infant death syndrome. Pediatrics, 82: 615-618.
25. Saiki, C., and Mortola, J.P. 1994. Ventilatory control in infant rats after daily episodes of anoxia. Pediatr. Res. 35: 490-493.
26. Scott, S.C., Inman, D.G., and Moss, I.R. 1990. Ontogeny of sleep/wake and cardiorespiratory behavior in unanesthetized piglets. Respir. Physiol. 80: 83-102.
27. Stanton, H.C., and Mueller, R.G. 1977. Performance of swine chilled during artificial rearing. Am. J. Vet. Res. 38: 1003-1006.
28. Stoltenberg, L., Rootwelt, T., Oyasaeter, S., Rognum, T.O., and Saugstad, O.D. 1993. Hypoxanthine, xanthine, and uric acid concentration in plasma, CSF, vitrous humor, and urine in piglets subjected to intermittent vs. continuous hypoxemia. Pediatr. Res. 34: 767-771.
29. Takano, N. 1968. Role of hypocapnia in the blood lactate accumulation during acute hypoxia. Respir. Physiol. 4: 32-41.
30. Thach, B.T., and Lawson, E.E. 1979. Death from upper airway obstruction: decrease survival time in 33-day old rabbits. Pediatr. Res. 13: 542.