Haemopoiesis in mice genetically lacking granulocyte-macrophage colony stimulating factor during chronic infection with Mycobacterium avium

Immunology and Cell Biology

Volumn 78, Issue 2, 2000, Pages 118-123

  Zhan, Y ^a,b   Cheers, C ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Bacterial infection; Colony stimulating factors; Knockout mice; Macrophages

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE DISRUPTION; HEMATOPOIESIS; HEMATOPOIETIC CELL; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MYCOBACTERIOSIS; MYCOBACTERIUM AVIUM; NONHUMAN;

ANIMALS; BONE MARROW CELLS; CHRONIC DISEASE; COLONY COUNT, MICROBIAL; COLONY-FORMING UNITS ASSAY; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; GENE DELETION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MYCOBACTERIUM AVIUM; NITRIC OXIDE; SPECIFIC PATHOGEN-FREE ORGANISMS; TIME FACTORS; TUBERCULOSIS;

ANIMALIA; BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM AVIUM; RODENTIA;

EID: 0034010103     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.2000.00891.x     Document Type: Article

References (30)

1. 1 Metcalf D. Haemopoietic regulators - Redundancy or subtlety? Blood 1993; 82: 3515-23.
2. 2 Gasson JC. Molecular physiology of granulocyte-macrophage colony stimulating factor. Blood 1991; 77: 1131-45.
3. 3 Lu L, Hsieh M, Oriss TB et al. Generation of DC from mouse spleen cell cultures in response to GM-CSF: Immunophenotypic and functional analyses. Immunology 1995; 84: 127-34.
4. 4 Stanley ES, Lieschke GJ, Grail D et al. Granulocyte/ macrophage colony-stimulating factor-deficient mice show no major perturbation of haemopoiesis but develop a characteristic pulmonary pathology. Proc. Natl Acad. Sci. USA 1994; 91: 5592-6.
5. 5 Dranoff GAD, Crawford M, Sadelain B et al. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 1994; 264: 713-16.
6. 6 Nishinakamura R, Nakayama N, Hirabayashi Y et al. Mice deficient for the IL-3/GM-CSF/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal. Immunity 1995; 2: 211 -22.
7. 7 Robb L, Drinkwater CC, Metcalf D et al. Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5. Proc. Natl Acad. Sci. USA 1995; 92: 9565-9.
8. 8 Zhan Y, Lieschke GJ, Grail D, Dunn AR, Cheers C. Essential roles for granulocyte-macrophage colony stimulating factor (GM-CSF) and granulocyte (G)-CSF in the sustained haemopoietic response of Listeria monocytogenes-infected mice. Blood 1998; 91: 863-9.
9. 9 Zhan Y, Basu S, Lieschke GJ, Grail D, Dunn AR, Cheers C. Functional deficiencies of peritoneal cells from gene targeted mice lacking G-CSF or GM-CSF. J. Leukoc. Biol. 1999; 65: 256-64.
10. 10 Stevenson M, Kongshavn PAL, Skamene E. Genetic linkage of resistance to Listeria monocytogenes with macrophage inflammatory response. J. Immunol. 1981; 127: 402-7.
11. 11 Young AM, Cheers C. Colony forming cells and colony stimulating activity during listeriosis in genetically resistant or susceptible mice. Cell. Immunol. 1986; 97: 227-37.
12. 12 Gilbertson B, Zhong J, Cheers C. Anergy, IFN-gamma production, and apoptosis in terminal infection of mice with Mycobacterium avium. J. Immunol. 1999; 163: 2073-80.
13. 13 Saunders B, Cheers C. Inflammatory response following intranasal infection with Mycobacterium avium complex - Role of T cell subsets and interferon-gamma. Infect. Immun. 1995; 63: 2282-7.
14. 14 Hestdal K, Ruscetti FW, Ihle JN et al. Characterisation and regulation of RB6-8C5 antigen expression on murine bone marrow cells. J. Immunol. 1991; 147: 22-8.
15. 15 Austyn JM, Gordon S. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 1981; 11: 805-15.
16. 51Cr release assay for the estimation of mouse cytotoxins. Transplantation 1968; 6: 761-4.
17. 17 Metcalf D. The Haemopoietic Growth Factors. Amsterdam: Elsevier, 1984.
18. 18 Cheers C, Haigh AM, Kelso A, Metcalf D, Stanley ER, Young AM. Production of colony stimulating factors during infection with an intracellular bacterium: Separate determinations of macrophage-, granulocyte-, granulocyte-macrophage-and multi-CSFs. Infect. Immun. 1988; 56: 247-51.
19. 19 Fortier AH, Polsinelli T, Green SJ, Nacy CA. Activation of macrophages for destruction of Francisella tularensis: Identification of cytokines, effector cells, and effector molecules. Infect. Immun. 1992; 60: 817-25.
20. 20 Dranoff G, Mulligan RC. Activities of granulocyte-macrophage colony-stimulating factor revealed by gene transfer and gene knockout studies. Stem Cells 1994; 12 (Suppl. 1): 173-84.
21. 21 Basu S, Dunn AR, Marino MW et al. Increased tolerance to endotoxin by granulocyte-macrophage colony-stimulating factor-deficient mice. J. Immunol. 1997; 159: 1412-17.
22. 22 Wada H, Noguchi Y, Marino MW, Dunn AR, Old LJ. T cell functions in granulocyte/macrophage colony-stimulating factor deficient mice. Proc. Natl Acad. Sci. USA 1997; 94: 12 557-61.
23. 23 Noguchi Y, Wada H, Marino MW, Old LJ. Regulation of IFN-gamma production in granulocyte-macrophage colony-stimulating factor-deficient mice. Eur. J. Immunol. 1998; 28: 3980-8.
24. 24 Vremec D, Lieschke GJ, Dunn AR, Robb L, Metcalf D, Shortman K. The influence of granulocyte/macrophage colony-stimulating factor on dendritic cell levels in mouse lymphoid organs. Eur. J. Immunol. 1997; 27: 40-4.
25. 25 Cheers C, McKenzie IFC, Pavlov H, Waid C, York J. Resistance and susceptibility of mice to bacterial infection. II. Course of listeriosis in resistant or susceptible mice. Infect. Immun. 1978; 19: 763-70.
26. 26 Lang RA, Metcalf D, Cuthbertson RA et al. Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage. Cell 1987; 51: 675-86.
27. 27 Tran HTT, Metcalf D, Cheers C. Antibacterial activity of peritoneal cells from transgenic mice producing high levels of GM-CSF. Immunology 1990; 71: 377-82.
28. 28 Nathan CF, Hibbs JB. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin. Immunol. 1991; 3: 65-70.
29. 29 Doi T, Ando M, Akaike T, Suga M, Sato K, Maeda H. Resistance to nitric oxide in Mycobacterium avium complex and its implication in pathogenesis. Infect. Immun. 1993; 61: 1980-9.
30. 30 Boockvar KS, Granger DL, Poston RM et al. Nitric oxide produced during murine listeriosis is protective. Infect. Immun. 1994; 62: 1089-100.