Characterization of the mouse nuclear orphan receptor TR2-11 gene promoter and its potential role in retinoic acid-induced P19 apoptosis

Biochemical Pharmacology

Volumn 60, Issue 1, 2000, Pages 127-136

  Lee, Chih Hao ^a   Wei, Li Na ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Apoptosis; Orphan receptor; P19 embryonal carcinoma cells; Retinoic acid; TR2 11 expression; TR2 11 gene

Indexed keywords

CELL NUCLEUS RECEPTOR; RETINOIC ACID; RETINOIC ACID RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; EXON; GENETIC ANALYSIS; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; SEQUENCE ANALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE; EXONS; GENE EXPRESSION REGULATION; MICE; PROMOTER REGIONS (GENETICS); RECEPTORS, THYROID HORMONE; TRETINOIN;

EID: 0034009588     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00311-7     Document Type: Article

References (36)

1. Chen J.D., Evans R.M. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature. 377:1995;454-457.
2. Horlein A.J., Naar A.M., Heinzel T., Torchia J., Gloss B., Kurokawa R., Ryan A., Kamel Y., Soderstrom M., Glass C.K., Rosenfeld M.G. Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature. 377:1995;397-403.
3. Horwitz K.B., Jackson T.A., Bain D.L., Richer J.K., Takimoto G.S., Tung L. Nuclear receptor coactivators and corepressors. Mol Endocrinol. 10:1996;1167-1177.
4. Ogryzko V.V., Schiltz R.L., Russanova V., Howard B.H., Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell. 87:1996;953-959.
5. Spencer T.E., Jenster G., Burcin M.M., Allis C.D., Zhou J., Mizzen C.A., McKenna N.J., Onate S.A., Tsai S.Y., Tsai M.J., O'Malley B.W. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 389:1997;194-198.
6. Kastner P., Mark M., Chambon P. Nonsteroid nuclear receptors What are genetic studies telling us about their role in real life? Cell. 83:1995;859-869.
7. Wei L.-N., Hsu Y. Identification of a new gene expressed specifically in early mouse embryos. Dev Growth Differ. 36:1994;187-196.
8. Lee C.-H., Copeland N.G., Gilbert D.J., Jenkins N.A., Wei L.-N. Genomic structure, promoter identification, and chromosomal mapping of a mouse nuclear orphan receptor expressed in embryos and adult testes. Genomics. 30:1995;46-52.
9. Lee C.-H., Chang L., Wei L.-N. Molecular cloning and characterization of a mouse nuclear orphan receptor expressed in embryos and testes. Mol Reprod Dev. 44:1996;305-314.
10. Lee C.-H., Chang L., Wei L.-N. Distinct expression patterns and biological activities of two isoforms of mouse orphan receptor TR2. J Endocrinol. 152:1997;245-255.
11. Sucov H.M., Murakami K.K., Evans R.M. Characterization of an autoregulated response element in the mouse retinoic acid receptor type β gene. Proc Natl Acad Sci USA. 87:1990;5392-5396.
12. Lee C.-H., Chinpaisal C., Wei L.-N. A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4. J Biol Chem. 273:1998;25209-25215.
13. Chinpaisal C., Lee C.-H., Wei L.-N. Mechanisms of the mouse orphan nuclear receptor TR2-11-mediated gene suppression. J Biol Chem. 273:1998;18077-18085.
14. Chinpaisal C., Chang L., Hu X., Lee C.-H., Wen W.-N., Wei L.-N. The orphan nuclear receptor TR2 suppresses a DR4 hormone response element of the mouse CRABP-I gene promoter. Biochemistry. 36:1997;14088-14095.
15. Lin T.-M., Young W.-J., Chang C. Multiple functions of the TR2-11 orphan receptor in modulating activation of two key cis-acting elements involved in the retinoic acid signal transduction system. J Biol Chem. 270:1995;30121-30128.
16. Lee C.-H., Chinpaisal C., Wei L.-N. Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2. Mol Cell Biol. 18:1998;6745-6755.
17. Lee H.-J., Chang C. Identification of human TR2 orphan receptor response element in the transcriptional initiation site of the simian virus 40 major late promoter. J Biol Chem. 270:1995;5434-5440.
18. Lee H.-J., Young W.-J., Shih C.C.-Y., Chang C. Suppression of the human erythropoietin gene expression by the TR2 orphan receptor, a member of the steroid receptor superfamily. J Biol Chem. 271:1996;10405-10412.
19. Frohman M.A., Dush M.K., Martin G.R. Rapid production of full-length cDNAs from rare transcripts Amplification using a single gene-specific oligonucleotide primer . Proc Natl Acad Sci USA. 85:1988;8998-9002.
20. Cathala G., Savouret J.F., Mendez B., West B.L., Karin M., Martial J.A., Baxier J.D. A method for isolation of intact translationally active ribonucleic acid. DNA. 2:1983;329-335.
21. Wagner M., Han B., Jessell T.M. Regional differences in retinoid release from embryonic neural tissue detected by an in vitro reporter assay. Development. 116:1992;55-66.
22. Wei L.-N., Blaner W.S., Goodman D.S., Nguyen-Huu M.C. Regulation of the cellular retinoid-binding proteins and their messenger ribonucleic acids during P19 embryonal carcinoma cell differentiation induced by retinoic acid. Mol Endocrinol. 3:1989;454-463.
23. Tatusova T.A., Madden T.L. BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences. FEMS Microbiol Lett. 174:1999;247-250.
24. Lin D.L., Wu S.Q., Chang C. The genomic structure and chromosomal location of the human TR2 orphan receptor, a member of the steroid receptor superfamily. Endocrine. 8:1998;123-134.
25. Lee C.-H., Wei L.-N. Characterization of an inverted repeat with a zero spacer (IR0)-type retinoic acid response element from the mouse nuclear orphan receptor TR2-11 gene. Biochemistry. 38:1999;8820-8829.
26. Mutoh H., Fung B.P., Naya F.J., Tsai M.-J., Nishitani J., Leiter A.B. The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression. Proc Natl Acad Sci USA. 94:1977;3560-3564.
27. Peers B., Leonard J., Sharma S., Teitelman G., Montminy M.R. Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol Endocrinol. 8:1994;1798-1806.
28. Okazawa H., Shimizu J., Kamei M., Imafuku I., Hamada H., Kanazawa I. Bcl-2 inhibits retinoic acid-induced apoptosis during the neural differentiation of embryonal stem cells. J Cell Biol. 132:1996;955-968.
29. Glozak M.A., Rogers M.B. Specific induction of apoptosis in P19 embryonal carcinoma cells by retinoic acid and BMP2 or BMP4. Dev Biol. 179:1996;458-470.
30. Mukasa T., Khoroku Y., Tsukahara T., Momoi M.Y., Kimura I., Momoi T. Wortmannin enhances CPP32-like activity during neuronal differentiation of P19 embryonal carcinoma cells induced by retinoic acid. Biochem Biophys Res Commun. 232:1997;192-197.
31. Glozak M.A., Rogers M.B. BMP4- and RA-induced apoptosis is mediated through the activation of retinoic acid receptor α and γ in P19 embryonal carcinoma cells. Exp Cell Res. 242:1998;165-173.
32. Fratelli M., Galli G., Minto M., Pasinetti G.M. Role of clusterin in cell adhesion during early phases of programmed cell death in P19 embryonic carcinoma cells. Biochim Biophys Acta. 1311:1996;71-76.
33. Galli G., Fratelli M. Activation of apoptosis by serum deprivation in a teratocarcinoma cell line Inhibition by l-acetylcarnitine . Exp Cell Res. 204:1993;54-60.
34. Thummel C.S. Dueling orphans - interacting nuclear receptors coordinate Drosophila metamorphosis. Bioessays. 19:1997;669-672.
35. Horn V., Minucci S., Ogryzko V., Adamson E.D., Howard B.H., Levin A.A., Ozato K. RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells. FASEB J. 10:1996;1071-1077.
36. Rodriguez-Leon J., Merino R., Macias D., Ganan Y., Santesteban E., Hurle J.M. Retinoic acid regulates programmed cell death through BMP signaling. Nat Cell Biol. 1:1999;125-126.