Effect of a combination of mild-temperature hyperthermia and nicotinamide on the radiation response of experimental tumors

Radiation Research

Volumn 153, Issue 3, 2000, Pages 327-331

  Ogawa, A ^a   Griffin, R J ^a   Song, C W ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL KILLING; CELL SURVIVAL; CONTROLLED STUDY; EXPERIMENTAL NEOPLASM; HUMAN; HYPERTHERMIA; MOUSE; OXYGENATION; PRIORITY JOURNAL; RADIOSENSITIVITY; TEMPERATURE; TUMOR BLOOD FLOW;

ANIMALIA;

EID: 0034009350     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2000)153[0327:EOACOM]2.0.CO;2     Document Type: Article

References (38)

1. G. E. Adams, The clinical relevance of tumor hypoxia. Eur. J. Cancer 26, 420-421 (1990).
2. S. Dische, Hypoxia and local tumor control. Part 2. Radiother. Oncol. 20, 9-11 (1991).
3. M. R. Horsman, Nicotinamide and other benzamide analogs as agents for overcoming hypoxic cell radiation resistance in tumors. A review. Acta Oncol. 34, 571-587 (1995).
4. 2) on the in vivo radiation response of a murine sarcoma. Int. J. Radiat. Oncol. Biol. Phys. 2, 903-911 (1977).
5. 2 and radiosensitivity of tumors by Fluosol-DA (20%) and carbogen. Cancer Res. 47, 442-446 (1987).
6. B. A. Teicher and C. M. Rose, Perfluorochcmical emulsions can increase tumor radiosensitivity. Science 223, 934-936 (1984).
7. C. W. Song, T. Hasegawa, H. C. Kwon, J. C. Lyons and S H. Levitt, Increase in tumor oxygenation and radiosensitivity caused by pentoxifylline. Radiat. Res. 130, 205-210 (1992).
8. A. Rojas, ARCON: accelerated radiotherapy with carbogen and nicotinamide. Br. J. Radiol. 24 (Suppl.), 174-178 (1992).
9. 2 in a manner compatible with its ability to increase relative tumor perfusion. Acta Oncol. 34, 385-389 (1995).
10. P. J. Hoskin, M. I. Saunders, H. Phillips, H. Cladd, M. E. Powell, K. Goodchild, M. R. Stratford and A. Rojas, Carbogen and nicotinamide in the treatment of bladder cancer with radical radiotherapy. Br. J. Cancer 76, 260-263 (1997).
11. M. Saunders and S. Dische, Clinical results of hypoxic cell radiosensitisation from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide. Br. J. Cancer 74 (Suppl. 27), S271-S278 (1996).
12. J. Denekamp and J. F. Fowler, ARCON - current status: summary of a workshop on preclinical and clinical studies. Acta Oncol. 36, 517-525 (1997).
13. J. M. Brown and A. J. Giaccia, The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 58, 1408-1416 (1998).
14. M. R. Horsman, D. J. Chaplin and J. M. Brown, Radiosensitization by nicotinamide in vivo: A greater enhancement of tumor damage compared to that of normal tissues. Radiat. Res. 109, 479-489 (1987).
15. I. Lee and C. W. Song, The oxygenation of murine tumor isografts and human tumor xenografts by nicotinamide. Radiat. Res. 130, 65-71 (1992).
16. D. J. Chaplin, M. R. Horsman and M. J. Trotter, Effect of nicotinamide on the microregional heterogeneity of oxygen delivery within a murine tumor. J. Natl. Cancer Inst. 82, 672-676 (1990).
17. 2 can be increased markedly by mild hyperthermia. Br. J. Cancer 74 (Suppl. 27), S217-S221 (1996).
18. K. Okajima, R. J. Griffin, K. Iwata, A. Shakil and C. W. Song, Tumor oxygenation after mild-temperature hyperthermia in combination with carbogen breathing: Dependence on heat dose and tumor type. Radiat. Res. 149, 294-299 (1998).
19. C. W. Song, A. Shakil, J. L. Osborn and K. Iwata, Tumor oxygenation is increased by hyperthermia at mild temperatures. Int. J. Hyperthermia 12, 367-373 (1996).
20. B. S. Nah, I. B. Choi, W. Y. Oh, J. L. Osborn and C. W. Song, Vascular thermal adaptation in tumors and normal tissue in rats. Int. J. Radiat. Oncol. Biol. Phys. 35, 95-101 (1996).
21. A. Shakil, J. L. Osborn and C. W. Song, Changes in oxygenation status and blood flow in a rat tumor model by mild temperature hyperthermia. Int. J. Radiat. Oncol. Biol. Phys. 43, 859-865 (1999).
22. R. J. Griffin, K. Okajima, A. Ogawa and C. W. Song, Radiosensitization of two murine tumors with mild temperature hyperthermia and carbogen breathing. Int. J. Radiat. Biol. 75, 1299-1306 (1999).
23. M. R. Horsman, D. J. Chaplin and J. Overgaard, Combination of nicotinamide and hyperthermia to eliminate radioresistant chronically and acutely hypoxic tumor cells. Cancer Res. 50, 7430-7436 (1990).
24. C. W. Song, Effect of local hyperthermia on blood flow and microenvironment: a review. Cancer Res. 44. 4721s-4730s (1984).
25. 2) and radiosensitivity. Cancer Res. 56, 5590-5593 (1996).
26. C. W. Song, A. Shakil, R. J. Griffin and K. Okajima, Improvement of tumor oxygenation status by mild temperature hyperthermia alone or in combination with carbogen. Semin. Oncol. 24, 626-632 (1997).
27. T. W. Secomb, R. Hsu, E. T. Ong, J. F. Gross and M. W. Dewhirst, Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors. Acta Oncol. 34, 313-316 (1995).
28. J. Lepock, K. H. Cheng, H. Al-Qysi, I. Sim, C. J. Koch and J. Kruuv, Hyperthermia-induced inhibition of respiration and mitochondrial protein denaturation in CHL cells. Int. J. Hyperthermia 3, 123-132 (1987).
29. J. A. Dickson, S. A. Shah, D. Waggott and W. B. Whailey, Tumor eradication in the rabbit by radiofrequency heating. Cancer Res. 37, 2162-2169 (1977).
30. M. R. Horsman, D. J. Chaplin and J. M. Brown, Tumor radiosensitization by nicotinamide: A result of improved perfusion and oxygenation. Radiat. Res. 118, 139-150 (1989).
31. S. Shall, ADP-ribose in DNA repair: a new component of DNA excision repair. Adv. Radiat. Biol. 11, 1-69 (1980).
32. X. Wang, K. Ohnishi, A. Takahashi and T. Ohnishi, Poly(ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation. Oncogene 17, 2819-2825 (1998).
33. E. Ben-Hur, H. Utsumi and M. M. Elkind, Inhibitors of poly (ADP-ribose) synthesis enhance radiation response by differentially affecting repair of potentially lethal versus sublethal damage. Br. J. Cancer 6(Suppl.), 39-42 (1984).
34. H. S. Lee, H. J. Park, J. C. Lyons, R. J. Griffin, E. A. Auger and C. W. Song, Radiation-induced apoptosis in different pH environments in vitro. Int. J. Radiat. Oncol. Biol. Phys. 38, 1079-1087 (1997).
35. M. E. Smulson, D. Pang, M. Jung, A. Dimtchev, S. Chasovskikh, A. Spoonde, C. Simbulan-Rosenthal, D. Rosenthal, A. Yakovlev and A. Dritschilo, Irreversible binding of poly(ADP)ribose polymerase cleavage product to DNA ends revealed by atomic force microscopy: possible role in apoptosis. Cancer Res. 58, 3495-3498 (1998).
36. H. J. Park, J. C. Lyons, T. Ohtsubo, C. Röedel, R. J. Griffin and C. W. Song, Apoptosis and cell cycle progression in an acidic environment after irradiation. Radiat. Res. 153, 295-304 (2000).
37. E. Kjellén, R. W. Pero, P. Nilsson and S. A. Hill, Effect of hyperthermia and/or nicotinamide on the radiation response of a C3H mammary carcinoma. Eur. J. Cancer Clin. Oncol. 25, 1733-1737 (1989).
38. M. R. Horsman, M. Hoyer, D. J. Honess, I. F. Dennis and J. Overgaard, Nicotinamide pharmacokinetics in humans and mice: A comparative assessment and the implications for radiotherapy. Radiother. Oncol. 27, 131-139 (1993).