A new central binaphthalene building block for michellamine syntheses

Synthesis

Volumn , Issue 3, 2000, Pages 383-388

  Bringmann, Gerhard ^a   Ortmann, Thomas ^a   Feineis, Doris ^a   Peters, Eva Maria ^b   Peters, Karl ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b MAX PLANCK INSTITUT FÜR FESTKÖRPERFORSCHUNG   (Germany)

Author keywords

Biaryls; Binaphthalene building blocks; Cyclizations; Michellamines; Natural products; Protecting groups; Wittig reaction

Indexed keywords

MICHELLAMINE B; NAPHTHALENE DERIVATIVE;

ALKYLATION; ARTICLE; CYCLIZATION; MOLECULAR INTERACTION; OXIDATION; REACTION ANALYSIS; SYNTHESIS; X RAY ANALYSIS;

EID: 0034008016     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-6340     Document Type: Article

References (41)

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32. 2Bu-t units.
33. (formula presented) (23) Previous binaphthalene syntheses (see Ref. 16) had used this bromine substituent only for achieving regioselectivity in the cyclization reaction to build up the second naphthalene ring, while in the synthesis described here, the halogen had to be conserved for its additional task as a leaving group in the scheduled later biaryl coupling step (here with the isoquinoline parts).
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