Outcome of clonal hemophagocytic lymphohistiocytosis: Analysis of 32 cases

Leukemia and Lymphoma

Volumn 37, Issue 5-6, 2000, Pages 577-584

  Imashuku, Shinsaku ^a   Hibi, Shigeyoshi ^a   Tabata, Yasuhiro ^a   Itoh, Etsuro ^b   Hashida, Tetsuo ^c   Tsunamoto, Kentaro ^d   Ishimoto, Koichi ^e   Kawano, Fumio ^f  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

^c Akashi Municipal Hospital Department of Surgery   (Japan)

^d MATSUSHITA MEMORIAL HOSPITAL   (Japan)

^e JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f NATIONAL HOSPITAL ORGANIZATION KUMAMOTO MEDICAL CENTER   (Japan)

Author keywords

Chromosomal abnormality; Clonality; Epstein Barr virus infection; Hemophagocytic lymphohistiocytosis

Indexed keywords

CORTICOSTEROID; CYCLOSPORIN; ETOPOSIDE; PREDNISOLONE; T LYMPHOCYTE RECEPTOR;

ADOLESCENT; ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; CHILD; CHROMOSOME ABERRATION; CLINICAL ARTICLE; EPSTEIN BARR VIRUS; FEMALE; HEMOPHAGOCYTIC SYNDROME; HISTIOCYTOSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOTHERAPY; INFANT; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE; T LYMPHOCYTE RECEPTOR GENE; VIRUS GENOME; ANEUPLOIDY; BONE MARROW TRANSPLANTATION; CELL CLONE; DRUG COMBINATION; GENE REARRANGEMENT; ISOLATION AND PURIFICATION; JAPAN; MORTALITY; MULTIMODALITY CANCER THERAPY; PATHOLOGY; PRESCHOOL CHILD; PROGNOSIS; REVIEW; TREATMENT OUTCOME; VIROLOGY; VIRUS INFECTION;

ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; ANEUPLOIDY; BONE MARROW TRANSPLANTATION; CHILD; CHILD, PRESCHOOL; CLONE CELLS; COMBINED MODALITY THERAPY; CYCLOSPORINE; DRUG THERAPY, COMBINATION; EPSTEIN-BARR VIRUS INFECTIONS; ETOPOSIDE; FEMALE; GENE REARRANGEMENT, T-LYMPHOCYTE; HERPESVIRUS 4, HUMAN; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; INFANT; JAPAN; MALE; PREDNISOLONE; PROGNOSIS; TREATMENT OUTCOME;

EID: 0034006686     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009058510     Document Type: Article

References (34)

1. Henter J-I, Arico M, Elinder G, Imashuku S & Janka G (1998). Familial hemophagocytic lymphohistiocytosis. Hematol Oncol Clin North Am 12:417-433.
2. Imashuku S (1997). Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatment. Int J Hematol 66:135-151.
3. Kaneko Y, Maseki N, Sakurai M, Ido M, Tsunematsu Y, Mizutani S, Hattori T, Shimizu H, Eguchi H, Oka T, Miyake M, Horikoshi Y & Suchi T (1995) Clonal and non-clonal karyotypically abnormal cells in haemophagocytic lymphohistiocytosis. Br J Haematol 90:48-55.
4. Dolezal MV, Kamel OW, van de Rijn M, Cleary ML, Sibley RK & Warnke RA (1995) Virus-associated hemophagocytic syndrome characterized by clonal Epstein-Barr virus genome. Am J Clin Pathol 103:189-194.
5. Chen J-S. Tzeng C-C, Tsao C-J, Su W-C, Chen T-Y, Jung Y-C. & Su I-J (1997) Clonal karyotype abnormalities in EBV-associated hemophagocytic syndrome. Hematologica 82:572-576.
6. Bird G, Peel D, McCarthy K & Williams H (1997) Epstein-Barr virus induced virus-associated hemophagocytic syndrome and monoclonal TCR-beta rearrangement: A case report. Hematol Oncol 15:47-52.
7. Owen G & Webb DKH (1995) Evidence of clonality in a child with haemophagocytic lymphohistiocytosis. Br J Haematol 89:681-682.
8. Imashuku S, Hibi S &Todo S (1997) Hemophagocytic lymphohistiocytosis in infancy and childhood. J Pediatr 130:352-357.
9. Imashuku S (1998). Treatment of Epstein-Barr virus (EBV)-related hemophagocytic syndrome. Nihonijishinpo 3885:37-45 (in Japanese).
10. Henter J-I, Elinder G & Ost A (1991) Diagnostic guidelines for hemophagocytic lymphohistiocytosis. Semin Oncol 18:29-33.
11. Henter J-I, Arico M, Egeler RM, Elinder G, Favara BE, Filipovich AH, Gadner H, Imashuku S, Janka-Schaub G, Komp D, Ladisch S, & Webb D for the HLH Study Group of the Histiocyte Society (1997) HLH-94: A treatment protocol for hemophagocytic lymphohistiocytosis. Med Pediatr Oncol 28:342-347.
12. Imashuku S, Hibi S, Ohara T, Iwai A, Sako M, Kato M, Arakawa H, Sotomatsu M, Kataoka S, Asami K, Hasegawa D, Kosaka Y, Sano K, Igarashi N, Maruhashi K, Ichimi R, Kawasaki H, Maeda M, Tanizawa A, Arai K, Abe T, Hisakawa H, Miyashita H & Henter J-I for the Histiocyte Society (1999) Effective control of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis with immunochemotherapy. Blood 93:1869-1874.
13. Telenti A, Marshall WF & Smith TF (1990) Detection of Epstein-Barr virus by polymerase chain reaction. J Clin Microbiol 28:2187-90.
14. nd eds. Cold Spring Harbor Laboratory Press, 1989.
15. Toyonaga B, Yanagi Y, Sucu-Foca N, Minden M & Mak TW (1984) Rearrangement of T-cell antigen receptor gene YT35 in human DNA from thymic T-cell lines and functional T-cell clones. Nature 311:385-387.
16. LeFranc MP & Rabbitts TH (1985) Two tandemly organized human genes encoding the T-cell γ constant region sequences show multiple rearrangement in different T-cell types. Nature 316:464-466.
17. Raab-Traub N & Flynn K (1986): The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation. Cell 47:883-889.
18. Yokota S, Hansen-Hagge TE, Ludwig WD, Reiter A, Raghavachar A, Kleihauer E & Bartram CR (1991) Use of polymerase chain reactions to monitor minimal residual disease in acute lymphoblastic leukemia patients. Blood 77:331-339.
19. Hettinger K, Fischer S, Panzer S & Panzer-Grumayer ER (1998) Multiplex PCR for TCR delta rearrangements: a rapid and specific approach for the detection and identification of immature and mature rearrangements in ALL. Br J Haematol 102:1050-1054.
20. ISCN (1995) An International System for Human Cytogenetic Nomenclature (ed. by F. Mitelman). S. Kager, Basel.
21. Kaplan EL & Meier P (1958) Non-parametric estimation from incomplete observations. J Am Statistic Assoc 53:457-481.
22. Kawaguchi H, Miyashita T, Herbst H, Niedobitek G, Asada M, Tsuchida M, Hanada R, Kinoshita A, Sakurai M, Kobayashi N & Mizutani S (1993) Epstein-Barr virus-infected T lymphocytes in Epstein-Barr virus-associated hemophagocytic syndrome. J Clin Invest 92:1444-1450.
23. Craig FE, Clare CN, Sklar JL & Banks PM (1992) T-cell lymphoma and the virus-associated hemophagocytic syndrome. Am J Clin Pathol 97:189-194.
24. Ishihara S, Okada S, Wakiguchi H, Kurashige T, Hirai K & Kawa-Ha K(1997): Clonal lymphoproliferation following chronic active Epstein-Barr virus infection and hypersensitivity to mosquito bites. Am J Hematol 54:276-281.
25. Millot F, Brizard F, Babin P, Canioni D, MacIntyre E, Levard G, Gambert C, Ricour C & Guihot F (1998) t(3;17)(q21;q23) in Epstein-Barr virus associated peripheral T-cell lymphoma: a pediatric case. Br J Haematol 100:331-334.
26. Okuda K, Sakamoto S. Deguchi T, Misawa S, Kashima K, Yoshihara T, Ikushima S, Hibi S & Imashuku S (1991) Hemophagocytic syndrome associated with aggressive natural killer cell leukemia. Am J Hematol 38:321-323.
27. Tien H-F. Su I-J, Tan J-L, Liu M-C, Lee F-Yu, Chen Y-C & Chuang S-M (1997) Clonal chromosomal abnormalities as direct evidence for clonality in nasal T/natural killer cell lymphomas. Br J Haematol 97:621-625.
28. Mateu R, Badell I, Alcala A, Estivill C, Rubiol E, Nomdedeu J & Soler J (1998): Aggressive natural killer cell leukemia: report of a case in a Caucasian boy. Haematologica 83:190-192.
29. Wong KF, Chan JKC & Kwong YL (1997) Identification of del(6)(q21q25) as a recurring chromosomal abnormality in putative NK cell lymphoma/leukemia. Br J Haematol 98:922-926.
30. Chen J-S, Lin K-H, Lin D-T, Chen R-L, Jou S-T & Su I-J (1998) Longitudinal observation and outcome of nonfamilial childhood haemophagocytic syndrome receiving etoposide-containing regimens. Br J Haematol 103:756-762.
31. Ishii E, Kimura N, Kato K, Sako M, Nagano M, Nakagawa A, Okamura T, Yamaguchi H, Kawa K & Hara T (1999) Clonal change of infiltrating T-cells in children with familial hemophagocytic lymphohistiocytosis. Cancer 85:1636-43.
32. Chou W-C, Chiang I-P, Tang J-L, Su I-J, Huang S-Y, Chen Y-C, Liu M-C, Lee F-Y. Wang C-H, Shen M-C, Chuang S-M & Tien H-F (1998) Clonal disease of natural killer large granular lymphocytes in Taiwan. Br J Haematol 103:1124-1128.
33. Imashuku S, Hibi S, Morinaga S, Takagi K, Chen J, Mugishima H, Ishii T, Sako M, Arakawa H & Kato M (1997) Haemophagocytic lymphohistiocytosis in association with granular lymphocyte proliferative disorders in early childhood: characteristic bone marrow morphology. Br J Haematol 96:708-714.
34. Lamy T, Drenou B, Fardel O, Amiot L, Grulois I, le Prise P-Y, Loughran TPJr & Fauchet R (1998) Multidrug resistance analysis in lymphoproliterative disease of large granular lymphocytes. Br J Haematol 100:509-515.